Author(s)

Manal I. Eid, Mary E. K. Wahba

Department of Analytical Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.

Two simple and sensitive spectrofluorimetric (method Ι) and spectrophotometric (method ΙΙ) methods have been developed for the determination of some chloride containing toothpastes and panthenol-containing cosmetic preparations respectively. Method Ι is based on quantitative fluorescence quenching of (terbium-salicylate-hexamine ternary complex) by fluoride which could be measured at λem/λex of 547 nm/322 nm. The ΔF-concentration plot was rectilinear over the concentration range of 0.5 - 20 μg/ml. Method ΙΙ depends reaction of panthenol with nitrobenzoxadiazole chloride (NBD-Cl) and measuring the absorbance of the resultant product at 480 nm. The absorbance-concentration plot was rectilinear over the concentration range of 2 - 20 μg/ml.

Panthenol; Spectrophotometry; Spectrofluorimetry; Stability Studies

M. I. Eid and M. E. K. Wahba, "Analytical and Stability Studies on Medical Cosmetics," American Journal of Analytical Chemistry, Vol. 3 No. 3, 2012, pp. 277-281. doi: 10.4236/ajac.2012.33037.