Diuretic activity of Phyllanthus niruri (Linn.) in rats

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DOI: 10.4236/health.2010.25076    5,676 Downloads   11,915 Views  Citations

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ABSTRACT

Aqueous extract of Phyllanthus niruri (200 mg/kg and 400 mg/kg. p.o. single dose) was tested for its diuretic activity and compared with the standard drug hydrochlorothiazide (10 mg/ kg p.o.; single dose). Significant increase in the volume of urine and excretion of sodium, potassium and chloride was recorded when aqueous extract of Phyllanthus niruri was administered to hydrated albino rats.

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Udupa, A. , ., S. , Benegal, A. , Prusty, V. , Kodancha, G. , Kumar, M. , Bhat, V. and Ratnakar, U. (2010) Diuretic activity of Phyllanthus niruri (Linn.) in rats. Health, 2, 511-512. doi: 10.4236/health.2010.25076.

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