Author(s)

Hengchang Ma, Zhikang Bao, Lianhua Bai, Wei Cao

Key Laboratory of Polymer Materials of Gansu Province, Key Laboratory of Eco-Environment-Related Polymer Materials, Ministry of Education, College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou, China.

Halogenated aluminates AlCl₃, applied as efficient chlorination reagent for hydroxyl groups of substitution alcohols is described. Primary and secondary benzylic alcohols could be transformed into corresponding aromatic halides with almost complete conversion and unique selectivity. As chlorination reagent, AlCl₃ has an incomparable advantage over others, such as low material cost, commercial availability as well as convenient product isolation.

Alcohols; Lewis Acid; Nucleophiles; Chlorination

H. Ma, Z. Bao, L. Bai and W. Cao, "A New Facile Route to Chlorination of Alcohols via Lewis Acid AlCl₃," International Journal of Organic Chemistry, Vol. 2 No. 1, 2012, pp. 21-25. doi: 10.4236/ijoc.2012.21004.