Dr. Margarida Sâncio da Cruz Fardilha
University of Aveiro, Portugal
Email: mfardilha@ua.pt
Qualifications
2004 Ph.D., Biology,
Centre for Cell Biology, University of Aveiro
1997 Post-graduate course, Gulbenkian PhD
Programme in Biology and Medicine
1996 B.Sc., Biochemistry, University of Porto
Publications(selected)
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Mariani, N. A., Silva, J. V., Fardilha, M., & Silva, E. J. (2023). Advances in non-hormonal male contraception targeting sperm motility. Human Reproduction Update, 29(5), 545-569.
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Matos, B., Publicover, S. J., Castro, L. F. C., Esteves, P. J., & Fardilha, M. (2023). Brain and testis: more alike than previously thought?. Advances in Surgical and Medical Specialties, 425-445.
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Leitão, C., Mignano, A., Estrela, M., Fardilha, M., Figueiras, A., Roque, F., & Herdeiro, M. T. (2022). The effect of nutrition on aging—A systematic review focusing on aging-related biomarkers. Nutrients, 14(3), 554.
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Santiago, J., Silva, J. V., Howl, J., Santos, M. A., & Fardilha, M. (2022). All you need to know about sperm RNAs. Human Reproduction Update, 28(1), 67-91.
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Santiago, J., Silva, J. V., Santos, M. A., & Fardilha, M. (2021). Fighting bisphenol A-induced male infertility: the power of antioxidants. Antioxidants, 10(2), 289.
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Quelhas, J., Santiago, J., Matos, B., Rocha, A., Lopes, G., & Fardilha, M. (2021). Bovine semen sexing: sperm membrane proteomics as candidates for immunological selection of X‐and Y‐chromosome‐bearing sperm. Veterinary Medicine and Science, 7(5), 1633-1641.
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Santiago, J., Silva, J. V., Alves, M. G., Oliveira, P. F., & Fardilha, M. (2019). Testicular aging: an overview of ultrastructural, cellular, and molecular alterations. The Journals of Gerontology: Series A, 74(6), 860-871.
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Henriques, M. C., Loureiro, S., Fardilha, M., & Herdeiro, M. T. (2019). Exposure to mercury and human reproductive health: A systematic review. Reproductive toxicology, 85, 93-103.
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Matos, B., Howl, J., Ferreira, R., & Fardilha, M. (2019). Exploring the effect of exercise training on testicular function. European Journal of Applied Physiology, 119, 1-8.
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Mesquita, M. Q., Dias, C. J., Gamelas, S., Fardilha, M., Neves, M. G., & Faustino, M. A. F. (2018). An insight on the role of photosensitizer nanocarriers for Photodynamic Therapy. Anais da Academia Brasileira de Ciências, 90, 1101-1130.
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Freitas, M. J., Vijayaraghavan, S., & Fardilha, M. (2017). Signaling mechanisms in mammalian sperm motility. Biology of reproduction, 96(1), 2-12.
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Korrodi-Gregorio, L., Soto-Cerrato, V., Vitorino, R., Fardilha, M., & Perez-Tomas, R. (2016). From proteomic analysis to potential therapeutic targets: functional profile of two lung cancer cell lines, A549 and SW900, widely studied in pre-clinical research. PLoS One, 11(11), e0165973.
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Luís Korrodi-Gregório, Joana Abrantes,
ThorstenMuller, José
Melo-Ferreira, Katrin Marcus, Odete A. B. da Cruz e Silva,Margarida Fardilhaand Pedro J. Esteves, 2013.Not so pseudo: the evolutionary
history of Protein Phosphatase 1 Regulatory Subunit 2 and related pseudogenes,
BMC Evolutionay Biology(accepted for publication).
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Luís Korrodi-Gregório, Ana Margarida
Lopes, Sara L. C. Esteves, Sandra Afonso, Ana Lemos de Matos, Andrey A.
Lissovsky, Odete A. B. da Cruz e Silva, Edgar F. da Cruz e Silva, Pedro José
Esteves andMargarida Fardilha,2013.An intriguing shift occurs in the
novel protein phosphatase 1 binding partner, TCTEX1D4: evidence of positive
selection in a Pika model, PLOS One(accepted
for publication).
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Luís Korrodi-Gregório, Joana Vieira
Silva, Luís Santos-Sousa, Maria João Freitas, Juliana Felgueiras andMargarida Fardilha,2013.TGFβ cascade regulation by PPP1 and
its interactors - impact on prostate cancer development and therapy. Journal of
Cellular and Molecular Medicine(accepted
for publication).
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Felgueiras, J., Silva, J.V.,Fardilha, M.,2013.Prostate cancer: the need for
biomarkers and new therapeutic targets. Journal of Zhejiang University SCIENCE
B.
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Rebelo S, Domingues SC, Santos M,Fardilha M,Esteves SL, Vieira SI, Vintém AP, Wu
W, da Cruz E Silva EF, da Cruz E Silva OA., 2013, Identification of a Novel
Complex AβPP:Fe65:PP1 that Regulates AβPP Thr668 Phosphorylation Levels.J
Alzheimers Dis. 2013 Jan 1;35(4):761-75. doi: 10.3233/JAD-130095.
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Korrodi-Gregório, Luis, Ferreira
Mónica, Vintém Paula Ana, Wu Wenjuan, Muller Thorsten, Marcus
Katrin, Vijayaraghavan Srinivasan, Brautigan L David, da Cruz e Silva A
Odete,Fardilha Margarida,da Cruz e Silva F Edgar.Identification and characterization of
two distinct PPP1R2 isoforms in human spermatozoa. BMC Cell Biology 2013,14:15 doi:10.1186/1471-2121-14-15.
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Luís Korrodi-Gregório, Sandra I.
Vieira, Sara L. C. Esteves, Joana V. Silva, Maria João Freitas, Ann-Kristin
Brauns, Georg Luers, Joana Abrantes, Pedro J. Esteves, Odete A. B. da Cruz e
Silva,Margarida Fardilhaand Edgar F. da Cruz e Silva.TCTEX1D4, a novel protein phosphatase
1 interactor: connecting the phosphatase to the microtubule network.Biology Open 2013 BIO20131065; Advance
Online Article March 11, 2013, doi:10.1242/bio.20131065.
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Margarida Fardilha, Mónica Ferreira,
Steven Pelech, Sandra Vieira, Sandra Rebelo, Mário Sousa, Alberto Barros,
Vladimiro Silva, Odete A. B. da Cruz e Silva and Edgar F. da Cruz e Silva†.Profiling Protein Phosphatases in
Human Sperm. OMICS, accepted in 7.1.2013.
Profile Details
https://www.ua.pt/pt/p/10331040
https://www.cienciavitae.pt/portal/en/AB13-016B-40A2
https://orcid.org/0000-0001-7459-9173
https://scholar.google.com/citations?user=_a5JaBMAAAAJ&hl=en