Dr. Wing Cheong Yam
Department of Microbiology
The University of Hong Kong, China
Honorary Associate Professor

Email: wcyam@hku.hk

Qualifications
2010 Founding Fellow member, Faculty of Science, Royal College of Pathologists, Australasia
2008 Fellow member of Royal College of Pathologists, United Kingdom

2005 Member of Royal College of Pathologists, United Kingdom
1994 Fellow member of Institute of Biomedical Sciences, United Kingdom
1989 Chartered member of the Institute of Biology, United Kingdom

Publications (Selected)

1. Tafess, K., Ng, T. T. L., Tam, K. K. G., Leung, K. S. S., Leung, J. S. L., Lee, L. K., ... & Siu, G. K. H. (2024). Genetic mechanisms of co-emergence of INH-resistant Mycobacterium tuberculosis strains during the standard course of antituberculosis therapy. Microbiology spectrum, 12(4), e02133-23.
2. Shao, Z., Tam, K. K. G., Achalla, V. P. K., Woon, E. C., Mason, A. J., Chow, S. F., ... & Lam, J. K. (2024). Synergistic combination of antimicrobial peptide and isoniazid as inhalable dry powder formulation against multi-drug resistant tuberculosis. International Journal of Pharmaceutics, 654, 123960.
3. Ng, T. T. L., Su, J., Lao, H. Y., Lui, W. W., Chan, C. T. M., Leung, A. W. S., ... & Siu, G. K. H. (2023). Long-read sequencing with hierarchical clustering for antiretroviral resistance profiling of mixed human immunodeficiency virus quasispecies. Clinical chemistry, 69(10), 1174-1185.
4. Su, J., Lui, W. W., Lee, Y., Zheng, Z., Siu, G. K. H., Ng, T. T. L., ... & Luo, R. (2023). Evaluation of Mycobacterium tuberculosis enrichment in metagenomic samples using ONT adaptive sequencing and amplicon sequencing for identification and variant calling. Scientific reports, 13(1), 5237.
5. Chan, A. C., Chan, M. C., Yip, P. C., Yam, W. C., Chau, C. H., Lam, R. F., ... & Leung, C. C. (2023). Grave impact of undetected rpoB I572F mutation on clinical course of multidrug-resistant tuberculosis: a case report. Hong Kong Medical Journal, 29(1), 70-72.
6. Su, J., Lui, W. W., Lee, Y., Zheng, Z., Siu, G. K. H., Ng, T. T. L., ... & Luo, R. (2023). Evaluation of Mycobacterium tuberculosis enrichment in metagenomic samples using ONT adaptive sequencing and amplicon sequencing for identification and variant calling. Scientific reports, 13(1), 5237.
7. Leung, K. S. S., Tam, K. K. G., Ng, T. T. L., Lao, H. Y., Shek, R. C. M., Ma, O. C. K., ... & Yam, W. C. (2022). Clinical utility of target amplicon sequencing test for rapid diagnosis of drug-resistant Mycobacterium tuberculosis from respiratory specimens. Frontiers in microbiology, 13, 974428.
8. Rajwani, R., Galata, C., Lee, A. W. T., So, P. K., Leung, K. S. S., Tam, K. K. G., ... & Siu, G. K. H. (2022). A multi-omics investigation into the mechanisms of hyper-virulence in Mycobacterium tuberculosis. Virulence, 13(1), 1088-1100.
9. Zhu, L., Lee, A. W. T., Wu, K. K. L., Gao, P., Tam, K. K. G., Rajwani, R., ... & Siu, G. K. H. (2022). Screening repurposed antiviral small molecules as antimycobacterial compounds by a lux-based phoP promoter-reporter platform. Antibiotics, 11(3), 369.
10. Leung, K. S. S., Ng, T. T. L., Wu, A. K. L., Yau, M. C. Y., Lao, H. Y., Choi, M. P., ... & Siu, G. K. H. (2021). Territorywide study of early coronavirus disease outbreak, Hong Kong, China. Emerging infectious diseases, 27(1), 196.
11. Siu, G. K. H., Lee, L. K., Leung, K. S. S., Leung, J. S. L., Ng, T. T. L., Chan, C. T. M., ... & Yip, S. P. (2020). Will a new clade of SARS-CoV-2 imported into the community spark a fourth wave of the COVID-19 outbreak in Hong Kong?. Emerging Microbes & Infections, 9(1), 2497-2500.
12. Tafess, K., Ng, T. T. L., Lao, H. Y., Leung, K. S. S., Tam, K. K. G., Rajwani, R., ... & Siu, G. K. H. (2020). Targeted-sequencing workflows for comprehensive drug resistance profiling of Mycobacterium tuberculosis cultures using two commercial sequencing platforms: comparison of analytical and diagnostic performance, turnaround time, and cost. Clinical chemistry, 66(6), 809-820.
13. Szeto, W., Yam, W. C., Huang, H., & Leung, D. Y. (2020). The efficacy of vacuum-ultraviolet light disinfection of some common environmental pathogens. BMC infectious diseases, 20, 1-9.
14. Leung, K. S. S., Ng, T. T. L., Wu, A. K. L., Yau, M. C. Y., Lao, H. Y., Choi, M. P., ... & Siu, G. K. H. (2020). A Territory-wide study of COVID-19 cases and clusters with unknown source in Hong Kong community: A clinical, epidemiological and phylogenomic investigation. medRxiv, 2020-03.

Profile Details

https://loop.frontiersin.org/people/288558/overview

https://www.researchgate.net/profile/Wing-Cheong-Yam