Prof. Carlos Martínez-A

Department of Immunology and Oncology,Centro Nacional de Biotecnología

Universidad Autónoma,Spain





1978   Ph.D., Clínica Puerta de Hierro, Madrid and Univ. Complutense, Spain
1974   B.Sc., Universidad Complutense, Spain


  1. Martínez-A C, RR Bernabé, P Pereira, A de la Hera, C Márquez, PA Cazenave and A Coutinho. Idiotypic helper T-cell repertoires are established early in life. Nature 317: 721-723, 1985 
  2. P. Pereira, A. Bandeira, A. Coutinho, M.A.R. Marcos, M.L. Toribio and C. Martínez -A. Vregion connectivity in T-cell repertoires. Ann. Rev.Immunol. 7: 209, 1989 
  3. Martínez-A C and A Coutinho. B-cell activation by helper cells is a two-step process. Nature 290, 60-61, 1981 
  4. Toribio ML, JC Gutierrez-Ramos, L Pezzi, MAR Marcos and C Martínez-A. Interleukin-2-dependent autocrine proliferation in T-cell development. Nature 342: 82-85, 1989 
  5. G. Kroemer and C. Martínez-A. The fail-safe paradigm of immunological tolerance: Conceptual and clinical implications. Lancet 338, 1246, 1991 
  6. Balomenos D, J Martín-Caballero, MI García, I Prieto, JM Flores, M Serrano & C Martínez-A. The cell cycle inhibitor p21 controls T cell proliferation and sex-linked lupus development. Nature Med 6, 171-176, 2000 
  7. Álvarez B, C Martínez-A, BMT Burgering & AC Carrera. Forkhead transcription factors contribute to execution of the mitotic program in mammals. Nature 413, 744-747, 2001 
  8. Mellado M, JMR Frade, S Mañes & C Martínez-A. Chemokine signaling and functional responses: the role of receptor dimerization and TK pathway activation. Annu Rev Immunol 19, 397-421, 2001 
  9. Mañes S, G del Real & C Martínez-A. Pathogens: raft hijackers. Nature Rev Immunol 3, 557-562, 2003 
  10. Hernanz-Falcón P, A Serrano, JM Rodriguez-Frade, D Juan, A del Sol, SF Soriano, F Roncal, L Gómez, A Valencia, C Martínez-A & M Mellado. Identification of amino acid residues critical for CCR5 dimerization. Nature Immunol 5, 216-223, 2004 
  11. Molon B, G Gri, M. Bettella, C Gómez-Moutón, A Lanzavecchia, C Martínez-A, S Mañes and A Viola. T cell costimulation by chemokine receptors. Nature Immunol. 6, 427-431, 2005 
  12. Jimenez-Baranda, S., Gomez-Mouton, C., Rojas, A., Martinez-Prats L., Mira, E., Lacalle, R., Valencia A., Dimitrov, D., Viola, A., Delgado, R., Martinez-A. C., and Mañes S. Filamin regulates actin-dependent clustering of HIV.1 receptors and cell infection. Nature Cell Biology, 9 (7) 838-847, 2007 
  13. Mercader N, E Leonardo, N Azpiazu, A Serrano, G Morata, C Martínez-A & M Torres. Conserved role of Meis1/Hth in specification of the proximodistal limb axis. Nature 402: 425-429, 1999. 
  14. D. García-Domingo, E. Leonardo, A. Grandien, P. Martínez, J P. Albar, J. C. Izpisúa- Belmonte and C. Martínez-A. Dido is a gene involved in onset of apoptosis in vitro, whose misexpression disrupts limb development. Proc. Natl. Acad. Sci. USA 96, 7992-7997, 1999. 
  15. Trachana, V., van Welly, K., Alonso Guerrero, A., Futterer, A. and Martinez-A. C.. Dido disruption leads to centrosome amplification and mitotic checkpoint defects compromising chromosome stability. Proc. Natl. Acad. Sci. USA, 104, 2691-2696, 2007. 
  16. Alonso Guerrero A, Cano Gomero M, Trachana V, Futterer A, Pacios-Bras C, Cigudos JC, Martínez-A C, van Wely KH Centromere-localized breaks indicate the generation of DNA damage by the mitotic spindle. Proc Natl Acad Sci USA, 107, 4159-4164, 2010.

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Last Updated: December 15, 2011.

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