Mir Ahamed Hossain

Email: hossain@kennedykrieger.org

Qualifications

1990  Ph.D., University of Calcutta, India

1982  M.Sc. , University of Calcutta, India

1979  B.Sc., University of Calcutta, India

Publications(Selected)

1. Chakraborty, A.K., Hossain, M.A., Makar, T.K. and Ghosh, J.J: Possible behavioral and biochemical marker of nicotine dependence. Indian J. Pharmacol., 18:107-109, 1986.
2. Hossain, M.A., Singh, I.S., Makar, T.K., Goswami, S. and Ghosh, J.J. Discontinuation effect of oxazepam and diazepam treatment on brain GABA metabolism in rat. Neurochem. Int., 11:49-53, 1987.
3. Hossain, M.A. and Ghosh, J.J: Atypical response of long-term flurazepam treatment on brain GABA metabolism. Medical Sci. Res., 16:759-760, 1988.
4. Hossain, M.A. and Ghosh, J.J: Involvement of GABAergic mechanism in benzodiazepine withdrawal phenomena. Eur. J. Pharmacol.,183(Suppl):1984-1985,1990.
5. Weiner, N, Hossain, M.A. and Masserano, J.M: The effects of electroconvulsive shock on catecholamine function in the locus coeruleus and hippocampus. J. Neural Transm., 34(suppl):3-9, 1991.
6. Hossain, M.A., Masserano, J.M. and Weiner, N: Effects of electroconvulsive shock on tetrahydrobiopterin and GTP-cyclohydrolase activity in the brain and adrenal gland of the rat. J. Neurochem., 59(6):2237-2243, 1992.
7. Hossain, M.A, Masserano, J.M. and Weiner, N: Comparative effects of electroconvulsive shock and haloperidol treatment on in vivo tyrosine hydroxylation and tetrahydrobiopterin in the brain of rats with 6-hydroxydopamine lesions. Brain Res., 598(1-2): 121- 126, 1992.
8. Hossain, M.A. and Weiner, N: Dopaminergic functional supersensitivity: Effects of chronic L-DOPA and carbidopa treatment in an animal model of Parkinson's disease. J. Pharmacol. Expt. Ther., 267(3):1105-1111, 1993.
9. Hossain, M.A., Masserano, J.M. and Weiner, N: Age related changes in tetrahydro- biopterin and GTP-cyclohydrolase activity in the brain and adrenal glands of rats. Neurobiology of Aging, 16(4): 627-632, 1995.
10. Hossain, M.A. and Weiner, N: Interactions of dopaminergic and GABAergic neurotransmission: Impact of 6-OHDA lesions into the substantia nigra of rats. J. Pharmacol. Expt. Ther., 275:237-244, 1995.
11. Johnston, P., Nam, M., Hossain, M.A., Indurti, R., Wilson, M.A. and Laterra J: Delivery of human fibroblast growth factor-1 gene to brain by genetically modified rat brain endothelial cells. J. Neurochem., 67:1643-1652, 1996.
12. Hossain M.A., Fielding K., Trescher W., Ho T., Wilson M.A. and Laterra J: Human FGF-1 gene delivery protects against quinolinate-induced striatal and hipppocampal injury in neonatal rats. Eur. J. Neurosci., 10:2490-2499, 1998.
13. Hossain M.A., Bouton M.L., Pevsner J. and Laterra J: Induction of vascular endothelial growth factor in human astrocytes by lead: Involvement of a protein kinase C/activator protein-1 complex-dependent and hypoxia-inducible factor 1-independent signaling pathway. J. Biol. Chem., 275:27874-27882, 2000.
14. Bouton C.M.L., Hossain M.A., Frelin L.P., Laterra J and Pevsner J: Microarray analysis of differential gene expression in lead-exposed astrocytes. Toxicol. Appl. Pharmacol., 176:34-53, 2001.
15. Walter K.A, Hossain M.A., Luddy C., Goel N., Reznik T.E. and Laterra J: Scatter factor/hepatocyte growth factor stimulation of glioblastoma cell cycle progression through G1 is c-Myc dependent, and independent of p27 suppression, Cdk2 activation, or E2F1-dependent transcription. Mol. Cell. Biol., 22(8): 2703-2715, 2002.
16. Hossain M.A., Russell J.C., Gomes R. and Laterra J: Neuroprotection by scatter factor/hepatocyte growth factor and FGF-1 in cerebellar granule neurons is phosphatidylinositol 3-kinase/Akt-dependent and MAPK/CREB-independent. J. Neurochem., 81(2): 365-378, 2002.
17. Lou H.R., Hattori H., Hossain M.A., Hester L., Huang Y., Lee-Kwon W, Donowitz M., Nagata E and Snyder S.H: Akt as a mediator of cell death. Proc. Natl. Acad. Sci., U.S.A., 100 (20): 11712-11717, 2003.
18. Hossain M.A., Russell J.C., Miknyoczki S., Ruggeri B., Lal B and Laterra J: Vascular endothelial growth factor mediates vasogenic edema in acute lead encephalopathy. Ann. Neurol. 55: 660-667, 2004.
19. Hossain M.A., Russell J.C., O’Brien R and Laterra J: Neuronal pentraxin 1: a novel mediator of hypoxic ischemic injury in neonatal brain. J. Neurosci., 24(17):4187-4196, 2004.
20. Russell J.C., Szuflita N., Khatri R., Laterra, J and Hossain, M.A: Transgenic expression of human FGF-1 protects against hypoxic ischemic injury in perinatal brain through intervening at caspase-XIAP signaling cascades. Neurobiology of Disease, 22: 677-690, 2006.
21. Russell, J.C., Blue, M., Johnston, M. V., Naidu, S and Hossain, M.A. Enhanced cell death in MeCP2 null cerebellar granule neurons exposed to excitotoxicity and hypoxia. Neuroscience, 150:563-574, 2007.
22. Hao, H., Yamamoto, A., Hossain, M.A., Younes, L and Mori, S. Quantitative cortical mapping of fractional anisotropy in developing rat brains. J. Neuroscience, 28 (6): 1427-1433, 2008.
23. Russell, J.C., Heather W., Szuflita, N. and Hossain, M.A. Nuclear translocation of X-linked inhibitor of apoptosis (XIAP) determines cell fate after hypoxia ischemia in neonatal brain. J. Neurochem., 106: 1357-1370, 2008.
24. Russell, J.C., Kishimoto, K., O’Driscoll, C. and Hossain, M.A. Neuronal Pentraxin 1 induction in hypoxic-ischemic neuronal death is regulated via a Glycogen Synthase Kinase-3α/β dependent mechanism. Cellular Signalling, 23:673-682, 2011. PMID: 21130869. PMCID: 3056287.
25. Sharma, J., Nelluru, G., Wilson,M.A., Johnston, M.V. and Hossain, M.A. Sex-specific activation of cell death signaling pathways in cerebellar granule neurons exposed to oxygen glucose deprivation followed by reoxygenation. ASN NEURO, 3 (2):85-97, 2011. PMID: 21382016, PMCID: 3072765.

Profile Details

Null