Dr. Bor Luen Tang,
Dept. Biochemistry, National University of Singapore, Singapore
Associate Professor
Email: bchtbl@nus.edu.sg
Qualifications
1994 Ph.D., National University of Singapore, Singapore
1991 M.Sc., Biochemistry, National University of Singapore, Singapore
1988 B.Sc., Biochemistry,National University of Singapore, Singapore
Publications
- Chen Y, Hor HH and Tang BL. AMIGO is expressed in multiple brain cells types and may regulate dendritic growth and neuronal survival. J. Cell Physiol. (in press) (doi: 10.1002/jcp.22958).
- Gee HY, Roh SH, Tang BL, Kim KH, and Lee MG. Rescue of DF508-CFTR trafficking via a GRASP-dependent unconventional secretion pathway. Cell 146: 746-760.
- Chua CE, Gan BQ and Tang BL (2011) Involvement of members of the Rab family and related small GTPases in autophagosome formation and maturation. Cell Mol. Life Sci. 68: 3349-3358.
- Chua CE and Tang BL (2011) Rabs, SNAREs and α-synuclein - membrane trafficking defects in synucleinopathies. Brain Res. Rev. 67: 268-281.
- Lim YS, Chua CE and Tang BL (2011) Rabs and other small GTPases in ciliary transport. Biol. Cell 103: 209-221.
- Tang BL, Gee HY and Lee MG (2011) The cystic fibrosis transmembrane conductance regulator (CFTR)’s expanding SNARE interactome. Traffic 12: 364-371.
- Chen Y and Tang BL (2011) Unique intracellular trafficking processes associated with NCAM and its intracellular signaling. Cell Adh. Migr. 17:69-74.
- Tang BL (2011) Sirt1's systemic protective roles and its promise as a target in anti-aging medicine. Trans. Res. 157: 276-284.
- Huang TH, Tsui HA, Tang BL, Hu KY and Chen A (2011) Emerging roles of Rab23 in the pathophysiology of mesangial cells – a proteomic analysis. Proteomics 11:380-394.
- Teng FY and Tang BL (2010) NF-қB signaling in neurite growth and neuronal survival. Rev. Neurosci. 21: 299-313.
- Gee HY, Tang BL, Kim KH and Lee MG (2010) Syntaxin 16 binds to CFTR and regulates its membrane trafficking in epithelial cells. J. Biol. Chem. 285: 35519-35527.
- Meng J, Xia W, Tang J, Tang BL and Liang F (2010) Dephosphorylation dependent inhibitory activity of juxtanodin on filamentous actin disassembly. J. Biol. Chem. 285: 28838-28849.
- Ong YS, Tang BL, Loo LS and Hong W (2010) p125A exists as part of the mammalian Sec13-Sec31 COPII subcomplex to facilitate ER-Golgi transport, J. Cell Biol. 190: 331-345.
- Chen Y, Gan BQ and Tang BL (2010) Syntaxin 16: unravelling cellular physiology through a ubiquitous SNARE molecule. J. Cell. Physiol. 225:326-332.
- Gan BQ and Tang BL (2010) Sirt1’s beneficial roles in neurodegenerative diseases – a CCT connection? Aging Cell 9:924-929.
- Tang BL (2010) Is Rab25 a tumor promoter or suppressor – context dependency on RCP status? Tumor Biol. 31: 359-361.
- Tang BL (2010) Resveratrol is neuroprotective because it is not a direct activator of Sirt1 - a hypothesis. Brain Res. Bull. 81:359-361.
- Chua CE, Lim YS and Tang BL (2010) Rab35 – a vesicular traffic regulating small GTPase with actin modulating roles, FEBS Lett. 584: 1-6.
- Tang BL and Chua CE (2010) Is systemic activation of Sirt1 beneficial for ageing-associated metabolic disorders? Biochem. Biophys. Res. Commun. 391: 6-10.
- Ng EL, Ng JJ, Liang F and Tang BL (2009) Rab22B is expressed in the CNS astroglia lineage and plays a role in epidermal growth factor receptor trafficking in A431 cells. J. Cell. Physiol. 221: 716-728.
- Tang BL (2009) Sirt1’s complex roles in neuroprotection. Cell. Mol. Neurobiol. 29: 1093-1103.
- Ng EL and Tang BL (2009) Rabs and cancer cell motility. Cell Motil. Cytoskeleton 66: 365-370.
- Tang BL (2009) Neuronal protein trafficking associated with Alzheimer’s disease: from APP and BACE to glutamate receptors. Cell Adh. Migr. 3: 118-128
- Chia WJ and Tang BL (2009) Emerging roles for Rab family GTPases in human cancer. Biochim. Biophys. Acta 1795: 110-116.
- Huang TH, Shui HA, Ka SM, Tang BL, Chao TK, Chen JS, Lin YF and Chen A. (2009) Rab 23 is expressed in mesangial cells and plays a role in development of focal segmental glomerulosclerosis. Nephrol. Dial. Transplant 24: 743-754.
- Teng FY, Hor CH and Tang BL (2009) Emerging cues mediating astroglia lineage restriction of progenitor cells in the injured/diseased adult CNS. Differentiation 77: 121-127.
- Hou Q, Wu YH, Grabsch H, Zhu Y, Leong SH, Ganesan K, Cross D, Tan LK, Tao J, Gopalakrishnan V, Tang BL, Kon OL and Tan P (2008) Integrative genomic identify Rab23 as an invasion mediator gene in diffuse gastric cancer. Cancer Res. 68: 4623-4630.
- Teng FY and Tang BL (2008) Nogo-A and Nogo-66 receptor in amyotrophic lateral sclerosis. J. Cell. Mol. Med. 12: 1199-1204.
- Ng EL and Tang BL (2008) Rab GTPases and their roles in brain neurons and glia. Brain Res. Rev. 58: 236-246.
- Teng FY and Tang BL (2008) Cell autonomous function of Nogo and reticulons - the emerging story at the endoplasmic reticulum. J. Cell.Physiol. 216: 303-308.