Prof. Zdenek Hel
Dept. of Pathology, Division of Molecular and Cellular Pathology
University of Alabama at Birmingham, USA

Email: zhel@uab.edu

Qualifications
1997   Ph.D., McGill University, Canada
1990   M.Sc., Charles University, Czech Republic

Publications (Selected)

1. Šmíd, M., Tuček, V., Madar, R., Tachezy, R., & Hel, Z. (2024). No evidence of a “healthy vaccinee effect” in COVID-19 vaccination data from the Czech Republic. International Journal of Infectious Diseases, 146.
2. Miková, E., Černý, V., Novotná, O., Petrásková, P., Boráková, K., Hel, Z., & Hrdý, J. (2024). Immature neutrophils in cord blood exert increased expression of genes associated with antimicrobial function. Frontiers in Immunology, 15, 1368624.
3. Sherwani, M. A., Duesman, S. J., Hel, Z., Raman, C., & Yusuf, N. (2024). Interferon Lambda Signaling Restrains Experimental Autoimmune Encephalomyelitis. Biomedicines, 12(3), 526.
4. Connelly, A. N., Huijbregts, R. P., Pal, H. C., Kuznetsova, V., Davis, M. D., Ong, K. L., ... & Hel, Z. (2022). Optimization of methods for the accurate characterization of whole blood neutrophils. Scientific Reports, 12(1), 3667.
5. Priesemann, V., Balling, R., Brinkmann, M. M., Ciesek, S., Czypionka, T., Eckerle, I., ... & Szczurek, E. (2021). An action plan for pan-European defence against new SARS-CoV-2 variants. The Lancet, 397(10273), 469-470.
6. Jimenez, R. V., Kuznetsova, V., Connelly, A. N., Hel, Z., & Szalai, A. J. (2019). C-reactive protein promotes the expansion of myeloid derived cells with suppressor functions. Frontiers in immunology, 10, 2183.
7. Litzman, J., Chovancová, Z., Bejdák, P., Litzman, M., Hel, Z., & Vlková, M. (2019). Common variable immunodeficiency patients display elevated plasma levels of granulocyte activation markers elastase and myeloperoxidase. International Journal of Immunopathology and Pharmacology, 33, 2058738419843381.
8. Vlkova, M., Chovancova, Z., Nechvatalova, J., Connelly, A. N., Davis, M. D., Slanina, P., ... & Hel, Z. (2019). Neutrophil and granulocytic myeloid-derived suppressor cell–mediated T cell suppression significantly contributes to immune dysregulation in common variable immunodeficiency disorders. The Journal of Immunology, 202(1), 93-104.
9. Polis, C. B., Achilles, S. L., Hel, Z., & Hapgood, J. P. (2018). Is a lower-dose, subcutaneous contraceptive injectable containing depot medroxyprogesterone acetate likely to impact women's risk of HIV?. Contraception, 97(3), 191-197.
10. Hapgood, J. P., Kaushic, C., & Hel, Z. (2018). Hormonal contraception and HIV-1 acquisition: biological mechanisms. Endocrine reviews, 39(1), 36-78.
11. Hel, Z., Xu, J., Denning, W. L., Helton, E. S., Huijbregts, R. P., Heath, S. L., ... & Mestecky, J. (2017). Dysregulation of systemic and mucosal humoral responses to microbial and food antigens as a factor contributing to microbial translocation and chronic inflammation in HIV-1 infection. PLoS pathogens, 13(1), e1006087.
12. Michel, K. G., Huijbregts, R. P., Gleason, J. L., Richter, H. E., & Hel, Z. (2015). Effect of hormonal contraception on the function of plasmacytoid dendritic cells and distribution of immune cell populations in the female reproductive tract. JAIDS Journal of Acquired Immune Deficiency Syndromes, 68(5), 511-518.
13. Hel, Z., Huijbregts, R. P., Xu, J., Nechvatalova, J., Vlkova, M., & Litzman, J. (2014). Altered serum cytokine signature in common variable immunodeficiency. Journal of clinical immunology, 34, 971-978.
14. Huijbregts, R. P., Michel, K. G., & Hel, Z. (2014). Effect of progestins on immunity: medroxyprogesterone but not norethisterone or levonorgestrel suppresses the function of T cells and pDCs. Contraception, 90(2), 123-129.
15. Bowers, N. L., Helton, E. S., Huijbregts, R. P., Goepfert, P. A., Heath, S. L., & Hel, Z. (2014). Immune suppression by neutrophils in HIV-1 infection: role of PD-L1/PD-1 pathway. PLoS pathogens, 10(3), e1003993.

Profile Details

WoS ResearcherID: KIH-9452-2024

https://orcid.org/0000-0002-4923-4794

https://scholars.uab.edu/2130-zdenek-hel

https://scholar.google.com/citations?user=v6_iCJIAAAAJ&hl=en

https://www.researchgate.net/profile/Zdenek-Hel