Prof. Yuchang Fu

Email: yfu@uab.edu

Qualifications

1990 Ph.D., Molecular Biology, Kyushu University, Japan

Publications (Selected)

1. Fu, Y., Luo, N., Klein, R. L., and Garvey, W. T. (2005). Adiponectin promotes adipocyte differentiation, Insulin sensitivity, and lipid accumulation. J. Lipid Research. 46, 1369-1379. PMID: 15834118
2. Fu, Y., Luo, L., Luo, N., and Garvey, W. T. (2006). Lipid metabolism mediated by adipocyte lipid binding protein (ALBP/aP2) gene expression in human THP-1 macrophages. Atherosclerosis. 188, 102-111. PMID: 16313911
3. Fu, Y., Luo, L., Luo, N., and Garvey, W. T. (2006). Proinflammatory cytokine production and insulin sensitivity regulated by overexpression of resistin in 3T3-L1 adipocytes. Nutrition & Metabolism. 3, 28. PMID: 16854242
4. Fu, Y., Luo, L., Luo, N., Zhu, X and Garvey, W. T. (2007). NR4A orphan nuclear receptors modulate insulin action and the glucose transport system: potential role in insulin resistance. J. Biol. Chem. 282, 31525-31533.PMID: 17785466
5. Tian, L., Luo, N., Klein, R. L., Chung, B. H., Garvey, W. T., and Fu, Y. (2009). Adiponectin reduces lipid accumulation in macrophage foam cells. Atherosclerosis. 202, 152-161. PMID: 18511057
6. Luo, N., Liu, J., Chung, B. H., Yang, Q-L., Klein, R. L., Garvey, W. T., and Fu, Y. (2010). Macrophage adiponectin expression improves insulin sensitivity and protects against inflammation and atherosclerosis. Diabetes. 59, 791-799.PMID: 20350970
7. Yin, K., Deng, X., Mo, Z-C., Zhao, G-J., Jiang, J., Cui, L-B., Tan, C-Z., Wen, G-B., Fu, Y., and Tang, C-K. (2011). Tristetraprolin-dependent posttranscriptional regulation of inflammatory cytokines mRNA expression by apolipoprotein A-I: role of ATP-binding membrane cassette transporter A1 and signal transducer and activator of transcription 3. J. Biol. Chem. In press.
8. Luo, N., Wang, X., Chung, B. H., Lee, M-H., Klein, R. L., Garvey, W. T., and Fu, Y. (2011). Effects of macrophage-specific adiponectin expression on lipid metabolism in vivo. AJP-Endocrinology and Metabolism. In press.
9. Fu, Y., Wang, Y., and Evans, S. M. (1998). Viral sequences enable efficient and tissue specific expression of transgenes in Xenopus. Nature Biotechnology. 16, 253-257. PMID: 9528004
10. Fu, Y., Yan, W., Mohun, T., and Evans, S. M. (1998). Vertebrate tinman homologues XNkx2-3 and XNkx2-5 are required for heart formation in a functionally redundant manner. Development. 125, 4439-4449. PMID: 9778503
11. Fu, Y., Luo, N., and Lopes-Virella, M. F. (2000). Oxidized LDL induces the expression of adipocyte lipid binding protein (ALBP/aP2) mRNA and protein in human THP-1 macrophages. J. Lipid Research. 41, 2017-2023. PMID: 11108735
12. Fu, Y., Luo, N., and Lopes-Virella, M. F. (2002). Upregulation of interleukin-8 expression by prostaglandin D2 metabolite 15-deoxy-delta12, 14 prostaglandin J2 (15d-PGJ2) in human THP-1 macrophages. Atherosclerosis. 160, 11-20. PMID: 11755918
13. Fu, Y., Luo, N., Lopes-Virella, M. F., and Garvey, W. T. (2002). The adipocyte lipid binding protein (ALBP/aP2) gene facilitates foam cell formation in human THP-1 macrophages. Atherosclerosis. 165, 259-269. PMID: 12417276
14. Fu, Y., Huang, Y., Bandyopadhyay, S., Virella, G., and Lopes-Virella, M. F. (2003). LDL immune complexes stimulate low density lipoprotein receptor expression in U937 histiocytes via extracellular signal-regulated kinase and AP-1. J. Lipid Research.  44, 1315-1321. PMID: 12730303
15. Fu, Y., Maianu, L., Melbert, B. R., and Garvey, W. T. (2004). Facilitative Glucose Transporter Gene Expression in Human Lymphocytes, Monocytes, and Macrophages: a Role for GLUT Isoforms 1, 3, and 5 in the Immune Response and Foam Cell Formation. Blood Cells, Molecules, & Diseases. 32, 182-190. PMID: 14757434