Biography


Prof. Bing-wen Soong

National Yang-Ming University, Chinese Taipei



Email: bwsoong@vghtpe.gov.tw


Qualifications

1998 Professor of Neurology and Neurosciences, National Yang-Ming University, Taiwan


Publications (Selected)

  1. Hung, H. C., Lin, J. H., Teng, Y. C., Kao, C. H., Wang, P. Y., Soong, B. W., & Tsai, T. F. (2025). A dominant negative Kcnd3 F227del mutation in mice causes spinocerebellar ataxia type 22 (SCA22) by impairing ER and Golgi functioning. The Journal of Pathology, 265(1), 57-68.
  2. Chen, H. C., Lee, L. H., Lirng, J. F., & Soong, B. W. (2024). MRl and MRS hints for the differentiation of cerebellar multiple system atrophy from spinocerebellar ataxia type II. Heliyon, 10(7).
  3. Soong, B. W., Manto, M., Brice, A., & Pulst, S. M. (2023). Trials for Cerebellar Ataxias. Springer International Publishing). https://doi. org/10, 1007, 978-3.
  4. Shaikh, A. G., Kim, J. S., Froment, C., Koo, Y. J., Dupre, N., Hadjivassiliou, M., ... & Manto, M. (2023). Scale for Ocular Motor Disorders in Ataxia (SODA): Procedures and Basic Understanding. In Trials for Cerebellar Ataxias: From Cellular Models to Human Therapies (pp. 347-361). Cham: Springer International Publishing.
  5. Ho, C. Y., Lai, H. Y., Wang, L. M., & Soong, B. W. (2023). Development of Mesenchymal Stem Cells Therapy for the Treatment of Polyglutamine SCA: From Bench to Bedside. Trials for Cerebellar Ataxias: From Cellular Models to Human Therapies, 499-530.
  6. Klockgether, T., Ashizawa, T., Brais, B., Chuang, R., Dürr, A., Fogel, B., ... & Ataxia Global Initiative. (2022). Paving the way toward meaningful trials in ataxias: an ataxia global initiative perspective. Movement disorders. New York. Vol. 37, no. 6 (June 2022), p. 1125-1130.
  7. Lee, Y. H., Tsai, Y. S., Chang, C. C., Ho, C. C., Shih, H. M., Chen, H. M., ... & Soong, B. W. (2022). A PIAS1 protective variant S510G delays polyQ disease onset by modifying protein homeostasis. Movement Disorders, 37(4), 767-777.
  8. Shaikh, A. G., Kim, J. S., Froment, C., Koo, Y. J., Dupre, N., Hadjivassiliou, M., ... & Manto, M. (2022). Scale for ocular motor disorders in Ataxia (SODA). Journal of the Neurological Sciences, 443, 120472.
  9. Chen, H. C., Lee, L. H., Lirng, J. F., & Soong, B. W. (2022). Radiological hints for differentiation of cerebellar multiple system atrophy from spinocerebellar ataxia. Scientific reports, 12(1), 10499.
  10. Wen, C. P., Lee, Y. C., Sun, Y. T., Huang, C. Y., Tsai, C. H., Chen, P. L., ... & Taiwan Stroke Registry Investigators. (2022). Low-density lipoprotein cholesterol and mortality in patients with intracerebral hemorrhage in Taiwan. Frontiers in Neurology, 12, 793471.
  11. Kuo, M. C., Lu, Y. C., Tai, C. H., Soong, B. W., Hu, F. C., Chen, M. L., ... & Wu, R. M. (2022). COQ2 and SNCA polymorphisms interact with environmental factors to modulate the risk of multiple system atrophy and subtype disposition. European Journal of Neurology, 29(10), 2956-2966.
  12. Soong, B. W., Yang, U. C., Yu-Shuen, T. S. A. I., Cheng, T. H., Chern, Y. J., Ming-Tsan, S. U., ... & LEE, Y. H. (2022). U.S. Patent Application No. 17/461,876.
  13. Zanni, G., Hsiao, C. T., Fu, S. J., Tang, C. Y., Capuano, A., Bosco, L., ... & Jeng, C. J. (2021). Novel KCND3 variant underlying nonprogressive congenital ataxia or SCA19/22 disrupt KV4. 3 protein expression and K+ currents with variable effects on channel properties. International Journal of Molecular Sciences, 22(9), 4986.
  14. Chiang, H. L., Fuh, J. L., Tsai, Y. S., Soong, B. W., Liao, Y. C., & Lee, Y. C. (2021). Expanding the phenotype of AFG3L2 mutations: Late-onset autosomal recessive spinocerebellar ataxia. Journal of the Neurological Sciences, 428, 117600.
  15. Hsu, S. L., Hsueh, H. W., Chen, S. Y., Chang, Y. Y., Tan, S., Hong, C. T., ... & Lee, Y. C. (2021). Clinical and genetic characterization of hereditary spastic paraplegia type 3A in Taiwan. Parkinsonism & Related Disorders, 87, 87-91.
  16. Hsiao, C. T., Tropea, T. F., Fu, S. J., Bardakjian, T. M., Gonzalez-Alegre, P., Soong, B. W., ... & Jeng, C. J. (2021). Rare gain-of-function KCND3 variant associated with cerebellar ataxia, parkinsonism, cognitive dysfunction, and brain iron accumulation. International Journal of Molecular Sciences, 22(15), 8247.
  17. Jih, K. Y., Lin, K. P., Tsai, P. C., Soong, B. W., Liao, Y. C., & Lee, Y. C. (2021). Investigating TBP CAG/CAA trinucleotide repeat expansions in a Taiwanese cohort with ALS. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 22(5-6), 442-447.
  18. Klockgether, T., Ashizawa, T., Brais, B., Chuang, R., Dürr, A., Fogel, B., ... & Ataxia Global Initiative. (2022). Paving the way toward meaningful trials in ataxias: an ataxia global initiative perspective. Movement disorders. New York. Vol. 37, no. 6 (June 2022), p. 1125-1130.
  19. Lee, Y. H., Tsai, Y. S., Chang, C. C., Ho, C. C., Shih, H. M., Chen, H. M., ... & Soong, B. W. (2022). A PIAS1 protective variant S510G delays polyQ disease onset by modifying protein homeostasis. Movement Disorders, 37(4), 767-777.
  20. Chen, H. C., Lee, L. H., Lirng, J. F., & Soong, B. W. (2022). Radiological hints for differentiation of cerebellar multiple system atrophy from spinocerebellar ataxia. Scientific reports, 12(1), 10499.
  21. Wen, C. P., Lee, Y. C., Sun, Y. T., Huang, C. Y., Tsai, C. H., Chen, P. L., ... & Taiwan Stroke Registry Investigators. (2022). Low-density lipoprotein cholesterol and mortality in patients with intracerebral hemorrhage in Taiwan. Frontiers in Neurology, 12, 793471.
  22. Soong, B. W., Yang, U. C., Yu-Shuen, T. S. A. I., Cheng, T. H., Chern, Y. J., Ming-Tsan, S. U., ... & LEE, Y. H. (2022). U.S. Patent Application No. 17/461,876.
  23. Chiang, H. L., Fuh, J. L., Tsai, Y. S., Soong, B. W., Liao, Y. C., & Lee, Y. C. (2021). Expanding the phenotype of AFG3L2 mutations: Late-onset autosomal recessive spinocerebellar ataxia. Journal of the Neurological Sciences, 428, 117600.
  24. Hsu, S. L., Hsueh, H. W., Chen, S. Y., Chang, Y. Y., Tan, S., Hong, C. T., ... & Lee, Y. C. (2021). Clinical and genetic characterization of hereditary spastic paraplegia type 3A in Taiwan. Parkinsonism & Related Disorders, 87, 87-91.
  25. Hsiao, C. T., Tropea, T. F., Fu, S. J., Bardakjian, T. M., Gonzalez-Alegre, P., Soong, B. W., ... & Jeng, C. J. (2021). Rare gain-of-function KCND3 variant associated with cerebellar ataxia, parkinsonism, cognitive dysfunction, and brain iron accumulation. International Journal of Molecular Sciences, 22(15), 8247.


Profile Details

https://orcid.org/0000-0002-3502-7153

https://scholar.google.com/citations?hl=zh-CN&user=NuT03IgAAAAJ

https://www.researchgate.net/profile/Bing-Wen-Soong-2

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