Biography

Prof. Moo-Ho Won

Kangwon National University, Republic of Korea


Email: mhwon@hallym.ac.kr


Qualifications
1991 Ph.D., Seoul National University
1981 D.V.M., Seoul National University

Publications (Selected)
  1. Lee, T. K., Kim, D. W., Park, J. H., Lee, C. H., Yang, S. R., Shin, M. C., ... & Ahn, J. H. (2025). Time course analysis of changes in neuronal loss, oxidative stress, and excitotoxicity in gerbil hippocampus following ischemia and reperfusion under hyperthermic conditions.
  2. Kim, D. W., Lee, T. K., Ahn, J. H., Yang, S. R., Shin, M. C., Cho, J. H., ... & Park, J. H. (2024). Porphyran Attenuates Neuronal Loss in the Hippocampal CA1 Subregion Induced by Ischemia and Reperfusion in Gerbils by Inhibiting NLRP3 Inflammasome-Mediated Neuroinflammation. Marine Drugs, 22(4), 170.
  3. Park, J. H., Lee, T. K., Kim, D. W., Ahn, J. H., Shin, M. C., Cho, J. H., ... & Kang, I. J. (2024). Neuroprotective effects of aucubin against cerebral ischemia and ischemia injury through the inhibition of the TLR4/NF-κB inflammatory signaling pathway in gerbils. International Journal of Molecular Sciences, 25(6), 3461.
  4. Kim, Y. H., Lee, T. K., Lee, J. C., Kim, D. W., Tae, H. J., Park, J. H., ... & Hong, S. (2023). Risperidone Administration Attenuates Renal Ischemia and Reperfusion Injury following Cardiac Arrest by Antiinflammatory Effects in Rats. Veterinary Sciences, 10(3), 184.
  5. Ahn, J. H., Lee, T. K., Kim, D. W., Shin, M. C., Cho, J. H., Lee, J. C., ... & Kim, Y. H. (2023). Therapeutic hypothermia after cardiac arrest attenuates hindlimb paralysis and damage of spinal motor neurons and astrocytes through modulating Nrf2/HO-1 signaling pathway in rats. Cells, 12(3), 414.
  6. Cui, M. Y., Fu, Y. Q., Li, Z. L., Zheng, Y., Yu, Y., Zhang, C., ... & Chen, B. H. (2023). Neuregulin-1/PI3K signaling effects on oligodendrocyte proliferation, remyelination and behaviors deficit in a male mouse model of ischemic stroke. Experimental neurology, 362, 114323.
  7. Lee, T. K., Kim, S. S., Lee, J. W., Kim, D. W., Lee, J. C., Kim, J. D., ... & Kim, Y. H. (2022). Brain Factor-7? Improves Cognitive Impairment Following Transient Ischemia and Reperfusion Injury in Gerbil Forebrain through Promoting Remyelination and Restoring Cholinergic and Glutamatergic Neurotransmission in the Hippocampus. Frontiers in Bioscience-Landmark, 27(12), 337.
  8. Kim, Y. H., Lee, T. K., Lee, J. C., Kim, D. W., Hong, S., Cho, J. H., ... & Kang, I. J. (2022). Therapeutic administration of oxcarbazepine saves cerebellar purkinje cells from ischemia and reperfusion injury induced by cardiac arrest through attenuation of oxidative stress. Antioxidants, 11(12), 2450.
  9. Hong, J., Lee, T. K., Kim, I. H., Lee, S., Jeon, B. J., Lee, J., ... & Kim, S. (2022). Anti-stress effects of Fameyes in in vitro and in vivo models of stresses. Laboratory Animal Research, 38(1), 39.
  10. Lee, T. K., Kim, D. W., Ahn, J. H., Lee, C. H., Lee, J. C., Lim, S. S., ... & Park, J. H. (2022). Protective effects of topical administration of laminarin in oxazolone-induced atopic dermatitis-like skin lesions. Marine Drugs, 20(11), 669.
  11. Lee, T. K., Lee, J. C., Kim, D. W., Lee, J. W., Kim, S. S., Kim, H. I., ... & Choi, S. Y. (2022). Effects of Brain Factor?7? against motor deficit and oxidative stress in a mouse model of MPTP?induced Parkinson's disease. Experimental and Therapeutic Medicine, 24(4), 635.
  12. Lee, S., Kim, I. H., Hong, J., Jeon, B. J., Kim, S. S., Lee, J. W., ... & Won, M. H. (2022). In Vitro and In Vivo Anti-Inflammatory Effects of TEES-10?, a Mixture of Ethanol Extracts of Ligularia stenocephala Matsum. & Koidz. and Secale cereale L. Sprout, on Gingivitis and Periodontitis. Dentistry Journal, 10(8), 143.
  13. Lee, C. H., Lee, T. K., Kim, D. W., Lim, S. S., Kang, I. J., Ahn, J. H., ... & Choi, S. Y. (2022). Relationship between neuronal damage/death and astrogliosis in the cerebral motor cortex of gerbil models of mild and severe ischemia and reperfusion injury. International Journal of Molecular Sciences, 23(9), 5096.
  14. Noh, Y. H., Hong, J., Lee, J. W., Kim, S. S., Lee, J. Y., Kang, I. J., ... & Han, S. S. (2022). A Complex of Cirsium japonicum var. maackii (Maxim.) Matisum. and Thymus vulgaris L. Improves Menopausal Symptoms and Supports Healthy Aging in Women. Journal of medicinal food, 25(3), 281-292.
  15. Lee, T. K., Kim, D. W., Sim, H., Lee, J. C., Kim, H. I., Shin, M. C., ... & Ahn, J. H. (2022). Hyperthermia accelerates neuronal loss differently between the hippocampal CA1 and CA2/3 through different HIF?1α expression after transient ischemia in gerbils. International Journal of Molecular Medicine, 49(4), 1-10.
  16. Noh, Y. H., Hong, J., Lee, J. W., Kim, S. S., Kang, I. J., Whang, W. K., ... & Won, M. H. (2022). YES-10 improves stress, tension, and Fatigue by reducing cortisol and IL-6 levels. Journal of Medicinal Food, 25(2), 205-212.
  17. Her, Y., Lee, T. K., Sim, H., Lee, J. C., Kim, D. W., Choi, S. Y., ... & Kim, S. S. (2022). Pinus thunbergii bark extract rich in flavonoids promotes hair growth in dorsal skin by regulating inflammatory cytokines and increasing growth factors in mice. Molecular medicine reports, 25(3), 1-9.
  18. Won, M. H., Lee, J. W., Lee, S., Kim, I. H., & Kim, S. S. (2022). Improvement of Learning and Memory Ability by Brain Factor-7?(BF-7?) Confirmed With fMRI and SPECT in Human. Food Supplements and Biomaterials for Health, 2(4).
  19. Hong, J., Noh, Y. H., Lee, J. W., Whang, W. K., Zheng, Y., Won, M. H., ... & Kim, S. S. (2022). Improvement of Attention, Long-term and Short-term Memory by Brain Factor-7?(BF-7?). Food Supplements and Biomaterials for Health, 2(1).
  20. Shin, M. C., Lee, T. K., Lee, J. C., Kim, H. I., Park, C. W., Cho, J. H., ... & Lee, C. H. (2022). Therapeutic effects of stiripentol against ischemia-reperfusion injury in gerbils focusing on cognitive deficit, neuronal death, astrocyte damage and blood brain barrier leakage in the hippocampus. The Korean Journal of Physiology & Pharmacology: Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology, 26(1), 47-57.
  21. Lee, T. K., Lee, J. C., Tae, H. J., Kim, H. I., Shin, M. C., Ahn, J. H., ... & Won, M. H. (2021). Therapeutic effects of risperidone against spinal cord injury in a rat model of asphyxial cardiac arrest: A focus on body temperature, paraplegia, motor neuron damage, and neuroinflammation. Veterinary Sciences, 8(10), 230.
  22. Park, M., Kim, J., Kim, T., Kim, S., Park, W., Ha, K. S., ... & Kim, Y. M. (2021). REDD1 is a determinant of low-dose metronomic doxorubicin-elicited endothelial cell dysfunction through downregulation of VEGFR-2/3 expression. Experimental & Molecular Medicine, 53(10), 1612-1622.
  23. Lee, T. K., Lee, J. C., Kim, J. D., Kim, D. W., Ahn, J. H., Park, J. H., ... & Kang, I. J. (2021). Populus tomentiglandulosa extract is rich in polyphenols and protects neurons, astrocytes, and the blood-brain barrier in gerbil striatum following ischemia-reperfusion injury. Molecules, 26(18), 5430.
  24. Park, J. H., Kim, J. D., Lee, T. K., Han, X., Sim, H., Kim, B., ... & Choi, S. Y. (2021). Neuroprotective and anti-inflammatory effects of Pinus densiflora bark extract in gerbil hippocampus following transient forebrain ischemia. Molecules, 26(15), 4592.
  25. Lee, T. K., Kim, D. W., Lee, J. C., Park, C. W., Sim, H., Ahn, J. H., ... & Choi, S. Y. (2021). Changes in cyclin D1, cdk4, and their associated molecules in ischemic pyramidal neurons in gerbil hippocampus after transient ischemia and neuroprotective effects of ischemic preconditioning by keeping the molecules in the ischemic neurons. Biology, 10(8), 719.


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