Prof. Merhnaz Gharaee-Kermani

Medical School, The University of Michigan, USA

Email: nazy@umich.edu

Qualifications

1999 Postdoctoral Fellowship. The University of Michigan, Medical School, Pathology

1996 Ph.D. The University of Michigan, Epidemiology Science

Publications (Selected)

1. Ma J., Gharaee-Kermani M., Kunju L., Hollingsworth J., Adler J., Arruda EM. and Macoska JA. (2012), Prostatic Fibrosis is Associated with Lower Urinary Tract Dysfunction, American Journal Urology, In Press.
2. Gharaee-Kermani M., Hu B., Phan SH. and Gyetko MR. (2012), The Role of Cancer Stem Cells in Development of Lung Cancer and its Potential to Resist the Most Therapeutic agent,Recent Current Medicinal Chemistry, Revised.
3. Hu B, Gharaee-Kermani M., Wu Z. and Phan SH. (2011), Essential Role of MeCP2 in the Regulation of Myofibroblasts Differentiation during Pulmonary Fibrosis, American Journal Pathology, 178, 4, 1500-1508.
4. Bhandary YP., ShettySK., Marudamuthu AS., Gyetko MR., Idell S., Gharaee-KermaniM., ShettyRS., Starcher BC. and Shetty S. (2011), Regulation of Alveolar Epithelial Cell Apoptosis and Pulmonary Fibrosis by Coordinate Expression of Components of the Fibrinolytic System, American Journal of Physiology-Lung Cellular and Molecular Physiology, PMID: 22140072.
5. Hu B., Gharaee-Kermani M., Wu Z. and Phan SH. (2010), Epigenetic Regulation of Myofibroblast Differentiation by DNA Methylation. American Journal of Pathology, 177, 1, 21-28.
6. Gharaee-Kermani M.,Hu B., Phan SH. and Gyetko MR. (2009), Recent Advances in Molecular Targets and Treatment of Idiopathic Pulmonary Fibrosis: Focus on TGFβsignaling and the Myofibroblast,Current Medicinal Chemistry, 16, 1400-1417.
7. Gharaee-Kermani M., Hu B., Phan SH. and Gyetko MR. (2008), The Role of Urokinase in Idiopathic Pulmonary Fibrosis and Implication for Therapy, Expert Opinion Developing Drugs, 17, 6, 905-916.
8. Gharaee-Kermani M., Hu B., Thannickal VJ., Phan SH. and Gyetko MR. (2007), Current and Emerging Drugs for Idiopathic Pulmonary Fibrosis, Expert Opinion Emerging Drugs, 12, 4, 627-646.
9. Gharaee-Kermani M., Gyetko MR., Hu B. and Phan SH. (2007), NewInsights into the Pathogenesis and Treatment of Idiopathic Pulmonary Fibrosis: A Potential Role for Stem Cells in the Lung Parenchyma and Implications for Therapy, Pharmaceutical Research, 24, 5, 819-841.
10. Hu B., Ullenbruch M., Jin H., Gharaee-Kermani M. and Phan SH. (2007), Essential Role of CCAAT/Enhancer Binding Protein alpha in Bleomycin-Induced Pulmonary Fibrosis, Journal of Pathology, 211, 4, 455-462.
11. Huaux F., Gharaee-Kermani M., Liu T., Morel V., McGarry B., Ullenbruch M., Kunkel SL., Wang J., Xing Z. and Phan SH. (2005), Role of Eotaxin-1 (CCL11) and CC Chemokine Receptor3 (CCR3) in Bleomycin-Induced Lung Injury and Fibrosis, American Journal of Pathology, 167, 6, 1485-1496.
12. Gharaee-Kermani M. and Phan SH. (2005), Molecular Mechanisms and Possible Treatment Strategies for Idiopathic Pulmonary Fibrosis.Current Pharmaceutical Design, 11, 30, 3943-3971.
13. Gharaee-Kermani M., Ullenbruch M. and Phan SH. (2005), Animal Models of Pulmonary Fibrosis, Methods in Molecular Medicine, 117, 251-259.
14. Gharaee-Kermani M., Hatano K., Nozaki Y, and Phan SH. (2005), Gender-Based Differences in Bleomycin-Induced Pulmonary Fibrosis, American Journal of Pathology, 166, 6, 1593-1606.
15. Phillips RJ., Mestas J.,Gharaee-Kermani M., Burdick MD., Sica A., Belperio JA., Keane MP. and Strieter RM. (2005), Epidermal Growth Factor and Hypoxia-Induced Expression of CXC Chemokine Receptor 4 on Non-Small Cell Lung Cancer Cells is Regulated by the Phosphatidylinositol 3-kinase/PTEN/AKT/Mammalian Target of Rapamycin Signaling Pathway and Activation of Hypoxia Inducible Factor-1 alpha. Journal of Biological Chemistry, 280, 23, 22473-2281.
16. Schramm CM., Puddington L., Wu C., Guernsey L., Gharaee-Kermani M., Phan SH. and Thrall RS. (2004), Chronic Inhaled Ovalbumin Exposure Induces Antigen-Dependent but not Antigen-Specific Inhalational Tolerance in a Murine Model of Allergic Airway Disease, American Journal of Pathology, 164, 295-304.
17. Gharaee-Kermani M. and Phan SH. (2004), The Roles of Apoptosis in Wound Healing and Pulmonary Fibrosis,Drug Design Reviews-Online, 1, 4, 313-323.
18. Gharaee-Kermani M., McCullumsmith RE., Charo IF., Kunkel SL. and Phan SH. (2003), CCR-2 is Required for Bleomycin-Induced Lung Fibrosis, Cytokine, 24, 6, 266-276.
19. Gharaee-Kermani M., Nozaki Y., Hatano K. and Phan SH. (2001), Lung Interleukin-4 Gene Expression in a Murine Model of Bleomycin-Induced Pulmonary Fibrosis, Cytokine, 15, 3, 138-147.
20. Gharaee-Kermani M. and Phan SH. (2001), Role of Cytokines and Cytokine Therapy in Wound Healing and Fibrotic Disease. Current Pharmaceutical Design. 7, 11, 1083-1103.

Last Updated: August, 2012