Dr. Carlos P. Sosa
Biomedical Informatics and Computational Biology
Mayo Clinic and University of Minnesota, Rochester, MN, USA
Adjunct Assistant Professor
Email: sosa0006@r.umn.edu
Research fields:
Bioinformatics
Drug Discovery
High-Performance
Computing
Qualifications
1986 Ph.D., Phys.
Chem., Wayne State University, USA
1980 Licentiate, Chem.,
San Carlos University, Guatemala
Publications (Selected)
-
P. Carrier, B. Long, R. Walsh, J. Dawson, C. P. Sosa, T. Tickle, B. Haas, T. William, “The Impact of High-Performance Computing Best Practice Applied to Next-Generation Sequencing Workflows”, Cray Users Group, May 2015, http://biorxiv.org/content/early/2015/04/07/017665
-
E. Godzaridis, S. Boisvert, F. Xia, M. Kandel, S. Behling, B. Long, C. P. Sosa, F. Laviolette, and J. Corbeil, “Human Analysts at Superhuman Scales: What Has Friendly Software To Do?”, Big Data, 1(4): 227-236(2013). doi:10.1089/big.2013.0031, http://online.liebertpub.com/doi/abs/10.1089/big.2013.0031
-
N.
Allsopp, A. Tabary, J. Follows, P. Vezolle, M. Hennecke, H. Reddy, F.
Ishibashi, C. Sosa, M. Paolini, S. Prakash, D. Quintero, O. Lascu, “Unfolding
IBM eServer Blue Gene Solution”, RedBook, SG24-6686-00, ISBN 0738494070Poughkeepsie, NY, September 20, 2005.
-
Scott
Vetter, Ben Gibbs, BalajiAtyam, Frank Berres, Bruno Blanchard, Lancelot
Castillo, Pedro Coelho, Nicolas Guerin, Lei Liu, Cesar DinizMaciel, Carlos
Sosa, RavikiranThirumalai “Advanced POWER Virtualization on IBM p5 Servers:
Architecture and Performance Considerations”, RedBook,
SG24-5768-01, ISBN 0738494070, Austin, Texas,
2005.
-
Gary
Lakner, Gary Schulten-Multz, and Carlos P Sosa "IBM
System Blue Gene Solution: Applications Development", RedBook,
SG24-7179, ISBN 0738489395, Rochester, Minnesota, 2007.
-
Carlos
P. Sosa "IBM System Blue Gene Solution: Blue Gene/P Application Development " First Edition, RedBook, SG24-7287, ISBN 0738488674, Rochester,
Minnesota, 2008.
-
E. W. Klee and C. P. Sosa, Invited Review
Article: “Computational classification of classically secreted proteins”, Drug
Discovery Today, 12,
234-239(2007). Supplemental material.
-
OysteinThorsen, Karl Jiang, Amanda Peters,
Brian Smith, Heshan Lin, Wu-chun Feng, Carlos P. Sosa, "Parallel Genomic
Sequence-Search on a Massively Parallel System", Proceedings of the 4th
international conference on Computing frontiers, Ischia, Italy, SESSION:
Mapping applications on parallel platforms table of contents, Pages: 59 - 68,
2007, ISBN:978-1-59593-683-7
-
X. Feng, K. W. Cameron, B. Smith, and C. P.
Sosa, “Building the Tree of Life on Terascale Systems”,
Proceedings of the 21st IEEE International Parallel and Distributed
Processing Symposium (IPDPS 07), March 2007.
-
K. Jiang, O. Thorsen, A. Peters, B. Smith,
and C. P. Sosa, "An Efficient Parallel Implementation of the
Hidden Markov Methods for Genomic Sequence-Search on a Massively Parallel
System", IEEE Transactions in Parallel
Distributed Systems, 19, 15-23(2008).
-
C. P. Sosa, "In Silico Classification of Secreted Proteins", Scirus Topic Page, March 2008.
-
H. Lin, P. Balaji, R. Poole, C. Sosa, X. Ma
and W. Feng, “Massively Parallel Genomic Sequence Search on the Blue Gene/P
Architecture,” IEEE/ACM International Conference for High-Performance
Computing, Networking, Storage and Analysis (SC), 2008.
-
M. Kandel, S. Behling, N. Schumann, B.
Long, C. P. Sosa, S. Boisvert, J. Corbeil, and L. Pesce, “Genomic Applications
on Cray supercomputers: NextGeneration Sequencing Workflow”, 2013 CUG
Proceedings, Napa Valley, CA, May 2013.
-
A.
Peters, M. Lundberg, T. Lang, C. P. Sosa, "High Throughput Computing
Validation for Drug Discovery Using the DOCK Program on a Massively Parallel
System", Redpaper 4410, Poughkeepsie, NY, April, 16 2008.
-
T-S.
Lee, G. M. Giambasu, C. P. Sosa, M. Martick, W. G. Scott and D. M. York, "Threshold
occupancy and specific cation binding modes in the hammerhead ribozyme active
site are required for active conformation", J. Mol. Biology, 388, 195-206(2009).
-
G. M.
Giambasu, T-S. Lee, C. P. Sosa, M. P. Robertson, W. G. Scott and D. M. York,
"Identification of dynamical hinge points of the L1 ligase molecular
switch", RNA, 16, 769-780(2010).
-
C. P.
Sosa, S. Behling, and D. Barrs, “Single Processor Tunning on the IBM POWER4
processor”, Education: pSeries, April 2004.
-
C. P.
Sosa, B. V. Atyam, P. Heyrman, N. Nayar, and J. Hilsabeck, “Life
Sciences Applications on IBM POWER5 and AIX 5L Version 5.3: Virtualization
Exploitation through Micro-Partitioning Implementation”, IBM Form
Number REDP-3966-00, March 2, 2005.
-
C. P.
Sosa, B. Atyam, and C. Strauss, “IBM Micro-Partitioning concepts, operations
and programming”, pSeries Education, 2005.
-
C. P.
Sosa and B. V. Atyam, “Performance Analysis of Simultaneous Multi-Threading on
IBM POWER5 eserverpSeries Systems Using Gaussian03”, Proceedings
of the Forum 2006 for the Frontier of Computational Science: Present and Future
Led by POWER, Kyushu University, Fukuoka, Japan, Aug. 2006, p[1-2].
Profile
Details
http://www.msi.umn.edu/~cpsosa//
Last Updated: 2015-7-1