Dr. Eusebio S Pires

Center for Research in Contraceptive and Reproductive Health Department of Cell Biology, University of Virginia, Charlottesville, VA, USA

Research Scientist

Email: eusebiopires@gmail.com

Qualifications

2008 Ph.D., University of Mumbai, Mumbai, India
2001 M.Sc., University of Mumbai, Mumbai, India

Research Fields 

Basic cell and reproductive biology 

Female Infertility 

Autoantibodies 

Translational medicine 

Female reproductive cancers 

Immunotherapy IVF and embryo transfers

Publications (Selected)

1. Naturally Occurring Anti-albumin Antibodies Are Responsible for False Positivity in Diagnosis of Autoimmune Premature Ovarian Failure. Eusebio S. Pires, Priyanka P. Parte, Perveen K. Meherji, Shagufta A. Khan and Vrinda V. Khole. Jour Histochem & Cytochem. 2006 April, 54 (4): 397-405.
2. Specific and Sensitive Immunoassays Detect Multiple Anti-ovarian Antibodies in Women With Infertility. Eusebio S. Pires, Pervin K. Meherji, Rama R. Vaidya, Firuza R. Parikh, Manish N. Ghosalkar and Vrinda V. Khole. Jour Histochem & Cytochem. 2007 December, 55(12): 1181-90.
3. Altered expression of progesterone receptors in testis of infertile men. Shadaan Abid, J Gokral, A Maitra, P Meherji, S Kadam, Eusebio S Pires and Deepak N Modi. Reprod Biomed Online. 2008 August, 17(2):175-84.
4. A ‘block’ in the road to fertility: autoantibodies to an immunodominant heat shock protein 90-bin human ovarian autoimmunity. Eusebio S Pires and Vrinda V Khole. Fertil Steril. 2009 October, 92(4):1395-1409.
5. Anti-ovarian antibodies: specificity, prevalence, multiple antigenicity and significance in human ovarian autoimmunity. Eusebio S Pires and Vrinda V Khole. Current Paradigm of Reproductive Immunology, 2009: 159-190 ISBN: 978-81-308-0373-9. Research Sign Post publishing house, Trivandrum, India .2009.
6. Multiplicity of molecular and cellular targets in human ovarian autoimmunity: an update.Eusebio S Pires. Jour Assis Reprd Genet. 2010 September; 27(9):519-524.
7. Can anti-ovarian antibody testing be useful in an IVF-ET clinic? Eusebio Pires, Firuza Parikh, Purvi Mande, Shonali Uttamchandani, Sujata Savkar and Vrinda Khole. JourAssis Reprd Genet. 2011 January, 28(1): 55-64
8. Anti-HSP90 autoantibodies in sera of infertile women identify a dominant, conserved epitope EP6 (380-389)of HSP90 protein. Eusebio S Pires, Asmita K Choudhury, Susan Idicula-Thomas and Vrinda V Khole. Reproductive Biology & Endocrinology. 2011 February, 9:16.
9. Oocyte specific oolemmal SAS1B involved in sperm binding through intra-acrosomal SLLP1 during fertilization. Monika Sachdev, Arabinda Mandal, Sabine Mulders, Laura C. Digilio, Subbarayalu Panneerdoss, Viswanadhapalli Suryavathi, Eusebio Pires, Kenneth L. Klotz, Laura Hermens, María Belén Herrero, Charles J. Flickinger, Marcel van Duin, John C. Herr. Developmental Biology 2012 363:40–51.
10. Validation of novel candidate biomarkers for diagnosis of ovarian autoimmunity. Vrinda Khole, Purvi Mande, Asmita Choudhary and Eusebio Pires. Advances in developing affordable in vitro molecular diagnostics, 2012: 139-151. Yashraj research foundation and Mahatma Gandhi Mission University.
11. SAS1B Protein [Ovastacin] Shows Temporal and Spatial Restriction to Oocytes in Several Eutherian Orders and Initiates Translation at the Primary to Secondary Follicle Transition. Eusebio S Pires, Callie Hlavin, Ellen Macnamara, Adey Ishola-Gbenla, Christa Doerwaldt, Catherine Chamberlain, Ken Klotz, Austin Herr, Aalok Khole, Olga Chertihin, Eliza Curnow, Sandford H Feldman, Arabinda Mandal, Jagathpala Shetty, Charles Flickinger and John C Herr. In Press Developmental Dynamics August 2013.

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