Prof. Saleh A. Naser

College of MedicineBurnett, School of Biomedical Sciences

University of Central Florida, USA

Professor

Email: Saleh.naser@ucf.edu

Qualifications

1993 Ph.D., New Mexico State University, Medical Microbiology

1988 M.Sc., University of Bridgeport, Biology/Clinical Sciences

1987 B.Sc., Yarmouk University, Medical Technology

Publications(Selected)

1. Naser SA, Ghobrial G, Romero C, Valentine JF. 2004.Culture of Mycobacterium avium subspecies paratuberculosis from the blood of patients with Crohn's disease. Lancet. 2004 Sep 18;364(9439):1039-44 (article).
2. Ghadiali AH, Strother M, Naser SA, Manning EJ, Sreevatsan S. 2004. Mycobacterium avium subsp. paratuberculosis strains isolated from Crohn's disease patients and animal species exhibit similar polymorphic locus patterns. J Clin Microbiol. 2004 Nov;42(11):5345-8 (article).
3. Naser SA, Valentine JF. 2004. Crohn's diseaseandMAP. Lancet. Dec 18;364(9452):2178-9 (Invited letter).
4. Romero C, Hamdi A, Valentine JF, Naser SA. 2005.Evaluation of Surgical Tissue From Patients with Crohn's Disease for the Presence of Mycobacterium avium Subspecies paratuberculosis DNA by In Situ Hybridization and Nested Polymerase Chain Reaction. Inflamm Bowel Dis. 2005. Feb;11(2):116-25 (article).
5. Naser SA.Mycobacterium in Crohn's disease is hard to digest.Gastroenterology. 2005 Oct;129(4):1359-60; 1360-1 (Invited letter).
6. Naser SA, Collins MT.Debate on the lack of evidence of Mycobacterium avium subsp. paratuberculosis in Crohn's disease.Inflamm Bowel Dis. 2005 Dec;11(12):1123-4 (letter).
7. Wu CW, Glasner J, Collins M, Naser S, Talaat AM.  Whole-genome plasticity among Mycobacterium avium subspecies: insights from comparative genomic hybridizations.  J Bacteriol.  2006 Jan;188(2):711-23 (article).
8. Chamberlin WM, Naser SA.  Integrating theories of the etiology of Crohn's disease.  On the etiology of Crohn's disease: questioning the hypotheses.  Med Sci Monit. 2006 Feb;12(2):27-33 (review).
9. Rumsey J, Valentine JF, Naser SA. Inhibition of phagosome maturation and survival of Mycobacterium avium subspecies paratuberculosis in polymorphonuclear leukocytes from Crohn's disease patients. Med Sci Monit. 2006 Mar 28;12(4):130-139 (article).
10. Le Puil M, Biggerstaff JP, Weidow BL, Price JR, Naser SA, White DC, Alberte RS. A novel fluorescence imaging technique combining deconvolution microscopy and spectral analysis for quantitative detection of opportunistic pathogens. J.Microbiol Methods. 2006.67:597-602 (article).
11. Naser S.A. and Naser NA.Mycobacterium paratuberculosis and Crohn’s disease; In. Emerging Infections 7; Edited by W.M. Scheld, D.C. Hooper and J.M. Hughes. ASM Press. 2007); Feb. 7:225-245.
12. Kaittanis C, Naser SA, Perez JM.One-step, nanoparticle-mediated bacterial detection with magnetic relaxation. Nano Lett. 2007 Feb;7(2):380-3.
13. Chamberlin W, Ghobrial G, Chehtane M, Naser SA. Successful treatment of a Crohn's disease patient infected with bacteremicMycobacterium
    paratuberculosis. Am J Gastroenterol. 2007 Mar;102(3):689-91.
14. Chamberlin W, Borody T, Naser S. MAP-associated Crohn's disease MAP, Koch's postulates, causality and Crohn's disease. Dig Liver Dis. 2007 Aug;39(8):792-4. Epub 2007 Jul 3.
15. Chamberlin W, Naser SA. Blood cultures of 19 Crohn's disease patients. Am J Gastroenterol. 2008 Mar;103(3):802-3.
16. Beckler DR, Elwasila S, Ghobrial G, Valentine JF, Naser SA. Correlation between rpoB gene mutation inMycobacterium avium subspecies paratuberculosisand clinical rifabutin and rifampicin resistance for treatment of Crohn's disease. World J Gastroenterol. 2008 May 7;14(17):2723-30.
17. Zhu X, Tu ZJ, Coussens PM, Kapur V, Janagama H, Naser S, Sreevatsan S. Transcriptional analysis of diverse strainsMycobacterium avium subspecies paratuberculosisin primary bovine monocyte derived macrophages. Microbes Infect. 2008 Oct;10(12-13):1274-82. Epub 2008 Jul 22.
18. Naser SA, Romero C, Ghobrial G, Ghonaim M, Naser NA, Valentine JF.Function Dysregulation in PBMC and PMNC in Crohn’s Disease. 2009. The Open Inflammation Journal. 2009 (Volume 2): 10: 24-30
19. Naser SA, Crawford J, Collins M, Valentine JF. Culture ofMycobacterium aviumsubspeciesparatuberculosis(MAP) from the Blood of Patients with Crohn’s disease: A follow-up blind multi center investigation.The Open Inflammation Journal. 2009 (volume 2). 2:22-23.
20. Shin AR, Kim HJ, Cho SN, Collins MT, Manning EJ, Naser SA, Shin SJ. Identification of seroreactive proteins in the culture filtrate antigen of Mycobacterium avium ssp. paratuberculosishuman isolates to sera from Crohn's disease patients. FEMS Immunol Med Microbiol. 2010 Feb;58(1):128-37.
21. Naser SA, Romero C, Urbina P, Naser N, Valentine J. Cellular infiltration and cytokine expression correlate with fistulizing state in Crohn's disease. Clin Vaccine Immunol. 2011 Sep;18(9):1416-9.
22. Pierce ES, Borowitz SM, Naser SA. The Broad Street pump revisited: dairy farms and an ongoing outbreak of inflammatory bowel disease in Forest, Virginia. Gut Pathog. 2011 Dec 23;3(1):20.
23. Naser SA, Khaja A, Fernandez M, Naser N., Elwasila S., Thanigachalam. S. Role of ATG16K, NOD2 and IL23R in Crohn’s disease pathogenesis. World Journal of Gasteroenterology. 2012 Feb.; 18(5): 412-424.
24. Kaittanis C , Boukhriss H , Santra S , Naser SA , Perez JM.Rapid and Sensitive Detection of an Intracellular Pathogen in Human Peripheral Leukocytes with Hybridizing Magnetic Relaxation Nanosensors. PLoS ONE. 2012:7(4): e35326. doi:10.1371/journal.pone.0035326.
25. Naser SA, Thanigachalam S, Dow CT, Collins MT.Exploring the role of Mycobacterium avium subspecies paratuberculosis in the pathogenesis of type 1 diabetes mellitus: a pilot study. Gut Pathog. 2013 Jun 13;5(1):14.

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