G. A. Nagana Gowda

Northwest Metabolomics Research center

University of Washington Seattle, USA

Research Assistant Professor



1999 Ph.D., Bangalore University, India, NMR spectroscopy

1985 M.Sc., University of Mysore, India, Analytical Chemistry

1983 B.Sc., University of Mysore, India, Physics, Chemistry and Mathematics

Publications (Selected)
  1. T. Ye, C. Zheng, S. Zhang, G. A. Nagana Gowda, O. Vitek, D. Raftery. (2012), “Add to Subtract”: A Simple Method to Remove Complex Background Signals from the 1H Nuclear Magnetic Resonance Spectra of Mixtures. Analytical Chemistry, 84(2), 994-1002.
  2. G. A. Nagana Gowda, F. Tayyari, T. Ye, Y. Suryani, S. Wei, N. Shanaiah, D. Raftery. (2010), Quantitative Analysis of Blood Plasma Metabolites Using Isotope Enhanced NMR Methods. Analytical Chemistry, 82, 8983-8990.
  3. S. Wei, J. Zhang, L. Liu, T. Ye, G. A. Nagana Gowda, F. Tayyari, D. Raftery. (2011), Ratio Analysis Spectroscopy (RANSY) for Selective Metabolite Identification in Complex Samples. Analytical Chemistry 83(10), 7616-7623.
  4. V. Asiago, L. Alvarado, N. Shanaiah, G. A. Nagana Gowda, K. Owusu-Sarfo, R. Ballas, D. Raftery. (2010), Early Detection of Recurrent Breast Cancer Using Metabolite Profiling. Cancer Research, 70(21), 8309-8318.
  5. Tao Ye, Shucha Zhang, Huaping Mo, Tayyari Fariba, G. A. Nagana Gowda, and Daniel Raftery. (2010), 13C-Formylation for Improved NMR Profiling of Amino Metabolites in Biofluids, Analytical Chemistry, 82(6), 2303-2309.
  6. N. K. Srivastava, S. Pradhan, B. Mittal, G. A. Nagana Gowda. (2010), High resolution NMR based analysis of serum lipids in Duchenne Muscular Dystrophy patients and its possible diagnostic significance, NMR Biomed. 23(1), 13-22.
  7. E. Appiah-Amponsah, N. Shanaiah, G. A. Nagana Gowda, K. Owusu-Sarfo, T. Ye, D. Raftery. (2009), Identification of 4-deoxythreonic acid present in human urine by using HPLC and NMR techniques, Journal of Pharmaceutical and Biomedical Analysis. 50, 878-885.
  8. T. Ye, H. Mo, N. Shanaiah, G. A. Nagana Gowda, S. Zhang, D. Raftery. (2009), Chemoselective 15N Tag for Sensitive and High-Resolution Nuclear Magnetic Resonance Profiling of the Carboxyl-Containing Metabolome, Analytical Chemistry, 81(12), 4882-4888.
  9. G. A. Nagana Gowda, N. Shanaiah, Amanda Cooper, Mary Maluccio, Daniel Raftery. (2009), Visualization of Bile Homeostasis using 1H NMR Spectroscopy as a Route for Assessing Liver Cancer, Lipids, 44, 27–35.
  10. G. A. Nagana Gowda, N. Shanaiah, Amanda Cooper, Mary Maluccio, Daniel Raftery. (2009), Bile Acids Conjugation in Human Bile is not Random: New Insights from 1H NMR Spectroscopy at 800 MHz, Lipids, 44(6): 527-535.
  11. G. A. Nagana Gowda, S. Zhang, H. Gu, V. Asiago, N. Shanaiah, D. Raftery. (2008), Metabolomics-Based Methods for Early Disease Diagnostics: A Review, Expert Review in Molecular Diagnosis, 8(5): 617-633.
  12. M. Srivastava, A. Sharma, V. K. Kapoor, G. A. Nagana Gowda. (2008), Stones from Cancerous and Benign Gallbladders are different: A Proton Nuclear Magnetic Resonance spectroscopy study. Hepatology Research, 38, 997–1005.
  13. S. Zhang, G. A. Nagana Gowda, V. Asiago, N. Shanaiah and D. Raftery. (2008), Correlative and quantitative 1H NMR-based metabolomics reveals specific metabolic pathway disturbances in diabetic rats, Analytical Biochemistry 383, 76–84.
  14. N. Shanaiah, A. Desilva, G. A. Nagana Gowda, M. A. Raftery, B. E. Hainline, D. Raftery. (2007), Metabolite class selection of amino acids in biofluids using chemical derivatization and their enhanced 13C NMR.Proceedings of the National Academy of Sciences (USA)104(28), 11540-11544.
  15. S. N. Akhtar, R.K. Singh, Y. Jadegoud,T. N. Dhole, A. Ayyagari, G. A. Nagana Gowda. (2007), In-vitro studies of RD human cells infection with Echovirus 11 using 1H NMR spectroscopy. NMR in Biomedicine, 20(4): 422-428.
  16. G. A. Nagana Gowda, B. S. Somashekar, O. B. Ijare, A. Sharma, V. K. Kapoor, C. L. Khetrapal. (2006), One step analysis of major bile metabolites in human bile using 1H NMR spectroscopy. Lipids 41, 577-589.
  17. G. A. Nagana Gowda, Omkar. B. Ijare, B. S. Somashekar, A. Sharma, V. K. Kapoor, C. L. Khetrapal. (2006), Single step analysis of individual conjugated bile acids in human bile using 1H NMR Spectroscopy, Lipids, 41, 591-603 (2006).
  18. A. Gupta, M. Dwivedi, G. A. Nagana Gowda, A. A. Mahdi, A. Jain, A, Ayyagari, R. Roy, M. Bhandari, C. L. Khetrapal. (2006), H NMR spectroscopy in the diagnosis of Klebsiella pneumoniae-induced urinary tract infection, NMR in Biomedicine, 19(8), 1055-1061.
  19. N. K. Srivastava, S. Pradhan, B. Mittal, R. Kumar, G. A. Nagana Gowda. (2006), An Improved, Single Step Standardized Method of Lipid Extraction from Human Skeletal Muscle Tissue, Analytical Letters 39(2), 297-315.
  20. 1H and13C NMR Characterization and Stereochemical assignments of Bile acids in aqueous mediaOmkar B. Ijare, B. S. Somashekar, Y. Jadegoud and G. A. Nagana Gowda. (2005), Lipids 40, 1031-1041.
  21. G. A. Nagana Gowda. (2004), Separation of the integrals of partially resolved doublets based on chemical shift evolution using non-selective RF pulses.Chemical Physics Letters397(4-6), 388-391.
  22. G. A. Nagana Gowda. (2003), Gradient Enhanced One-Dimensional Pulse Schemes for Quaternary and Methylene Carbon Detection. Magnetic Resonance in Chemistry 41, 599-602.
  23. G. A. Nagana Gowda. (2002), Improved Sensitivity and Gradient Enhanced Multiplicity Edited Heteronuclear Correlation Technique. Chemical Physics Letters, 353, 49-54.
  24. G. A. Nagana Gowda.(2001), One-dimensional pulse technique for detection of only quaternary carbons. Magnetic Resonance in Chemistry, 39, 581-585.
  25. G. A. Nagana Gowda. (1996), Spectral simplification and “pseudo decoupling" in one dimensional proton NMR spectra using pulsed field gradients. Journal of Magnetic Resonance, 118A, 113-116.
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