Biography

Dr. Wuguo Chen

Lineberger Comprehensive Cancer Center

Department of Microbiology and Immunology

University of North Carolina at Chapel Hill, USA


Email: wuguo_chen@med.unc.edu


Qualifications

2006 PH.D., Life Science College of Wuhan University, China

2002 M.S., Central China Normal University, China


Publications

  1. Wuguo Chen, Sang-Hoon Sin, Kwun Wah Wen, Blossom Damania, Dirk P. Dittmer Hsp90 Inhibitors are efficacious against Kaposi Sarcoma by enhancing the degradation of the essential viral gene LANA, of the Viral Co-Receptor EphA2 as well as other client proteins. Plos Pathogens, 2012, 8(11): e1003048.
  2. Wuguo Chen, Dirk P. Dittmer Ribosomal protein S6 interacts with the latency-associated nuclear antigen of Kaposi sarcoma-associated herpesvirus. Journal of Virology, 2011, 85(18):9495-9505.
  3. Wuguo Chen, Michelle Staudt, Christin E. Burd, Isaac Hilton and Dirk P. Dittmer Distinct p53:p53, p53:LANA and LANA:LANA complexes in Kaposi sarcoma-associated herpesvirus (KSHV) lymphomas. Journal of Virology, 2010, 84(8):3898-908.
  4. Changjin Dong, Jiamin Zhang, Hai Huang, Wuguo Chen, Yuanyang Hu Pathogenicity of a new China variety of Metarhizium anisopliae (M. Anisopliae var. Dcjhyium) to subterranean termite Odontotermes formosanus. Microbiological Research, 2009. 164(1):27-35.
  5. Wuguo Chen, Yuanyang Hu, Yang Li, Zheng Yu, Changjin Dong, Dawei Cai, Jiamin Zhang Characterization of the RNA-binding domains in protein p36 of Heliothis armigera cypovirus 14. Virus research, 2007, 125(2):211-8.
  6. Yanqiu Li, Jiamin Zhang, Yang Li, Li Tan, Wuguo Chen, Haishan Luo, Yuanyang Hu Phylogenetic analysis of Heliothis armigera cytoplasmic polyhedrosis virus type 14 and a series of dwarf segments found in the genome. Journal of General Virology, 2007, 88, 991-997.
  7. Changjin Dong, Jiamin Zhang, Wuguo Chen, Hai Huang, Yuanyang Hu Characterization of a newly discovered China variety of Metarhizium anisopliae (M. anisopliae var. dcjhyium) for virulence to termites, isoenzyme, and phylogenic analysis. Microbiological Research, 2007, 162 (1), 53-61.
  8. Wuguo Chen, Jiamin Zhang, Changjin Dong, Bo Yang, Yanqiu Li, Chuanfeng Liu, Yuanyang Hu Identification of transmembrane domain of a membrane associated protein NS5 of Dendrolimus punctatus cytoplasmic polyhedrosis virus. Journal of Biochemistry and Molecular Biology, 2006, 39 (4), 412-417.
  9. Yang Li, Li Tan, Yanqiu Li, Wuguo Chen, Jiamin Zhang Yuanyang Hu Identification and genome characterization of Heliothis armigera cypovirus types 5 and 14 and Heliothis assulta cypovirus type. Journal of General Virology, 2006, 14 (87), 387-394.
  10. Bo Yang, Jiamin Zhang, Dawei Cai, Doulin Li, Wuguo Chen, Hong Jiang, Yuanyang Hu Biochemical characterization of Periplaneta fuliginosa densovirus non-structural protein NS1.Biochemical and Biophysical Research Communications, 2006, 342 (4), 1188-1196.
  11. Chuanfeng Liu, Jiamin Zhang, Junping Wang, Jie Lu, Wuguo Chen, Dawei Cai, Yuanyang Hu Sequence analysis of coat protein gene of Wuhan nodavirus isolated from insect. Virus research, 2006, 121(1), 17-22.


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