Dr. Manuel Narváez Peláez
Department of
Human Physiology and Sport Medicine, Faculty of Medicine
University of Málaga, Spain
Email: mnarvaez@uma.es
Qualifications
2012 Ph.D., University of Malaga, Spain
2005 M.D., Medicine and Surgery, University of Malaga, Spain
Publications (Selected)
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Borroto-Escuela DO,
Romero-Fernandez W, Garriga P, Ciruela F, Narvaez M, Tarakanov AO, Palkovits M,
Agnati LF, Fuxe K. G protein-coupled receptor heterodimerization in the brain.
Methods Enzymol. 2013;521:281-94.
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Fuxe K, Borroto-Escuela DO,
Romero-Fernandez W, Tarakanov AO, Calvo F, Garriga P, Tena M, Narvaez M, Millón
C, Parrado C, Ciruela F, Agnati LF, Narvaez JA, Díaz-Cabiale Z. On the
existence and function of galanin receptor heteromers in the central nervous
system. Front Endocrinol (Lausanne). 2012;3:127
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Borroto-Escuela DO,
Romero-Fernandez W, Pérez-Alea M, Narvaez M, Tarakanov AO, Mudó G, Agnati LF,
Ciruela F, Belluardo N, Fuxe K. The existence of FGFR1-5-HT1A receptor
heterocomplexes in midbrain 5-HT neurons of the rat: relevance for
neuroplasticity. J Neurosci. 2012 May 2;32(18):6295-303.
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Borroto-Escuela DO,
Romero-Fernandez W, Mudó G, Pérez-Alea M, Ciruela F, Tarakanov AO, Narvaez M,
Di Liberto V, Agnati LF, Belluardo N, Fuxe K. Fibroblast growth factor receptor
1- 5-hydroxytryptamine 1A heteroreceptor complexes and their enhancement of
hippocampal plasticity. Biol Psychiatry. 2012 Jan 1;71(1):84-91
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Romero-Fernandez W,
Borroto-Escuela DO, Tarakanov AO, Mudó G, Narvaez M, Pérez-Alea M, Agnati LF,
Ciruela F, Belluardo N, Fuxe K. Agonist-induced formation of FGFR1 homodimers
and signaling differ among members of the FGF family. Biochem Biophys Res
Commun. 2011 Jun 17;409(4):764-8
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Díaz-Cabiale Z, Parrado C, Narváez
M, Puigcerver A, Millón C, Santín L, Fuxe K, Narváez JA. Galanin
receptor/Neuropeptide Y receptor interactions in the dorsal raphe nucleus of
the rat. Neuropharmacology. 2011 Jul-Aug;61(1-2):80-6
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Díaz-Cabiale Z, Parrado C, Narváez
M, Millón C, Puigcerver A, Fuxe K, Narváez JA. Neurochemical modulation of
central cardiovascular control: the integrative role of galanin. EXS.
2010;102:113-31
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Borroto-Escuela DO, Correia PA,
Romero-Fernandez W, Narvaez M, Fuxe K, Ciruela F, Garriga P . Muscarinic
receptor family interacting proteins: role in receptor function. J Neurosci
Methods. 2011 Feb 15;195(2):161-9
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Borroto-Escuela DO,
Romero-Fernandez W, Tarakanov AO, Gómez-Soler M, Corrales F, Marcellino D,
Narvaez M, Frankowska M, Flajolet M, Heintz N, Agnati LF, Ciruela F, Fuxe K.
Characterization of the A2AR-D2R interface: focus on the role of the C-terminal
tail and the transmembrane helices. Biochem Biophys Res Commun. 2010 Nov 26;402(4):801-7.
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Díaz-Cabiale Z, Parrado C,
Narváez M, Millón C, Puigcerver A, Fuxe K, Narváez JA. The Galanin N-terminal
fragment (1-15) interacts with neuropeptide Y in central cardiovascular
control: Involvement of the NPY Y2 receptor subtype. Regul Pept. 2010 Aug
9;163(1-3):130-6
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Borroto-Escuela DO, Correia PA,
Perez Alea M, Narvaez M, Garriga P, Fuxe K, Ciruela F. Impaired M(3) muscarinic
acetylcholine receptor signal transduction through blockade of binding of
multiple proteins to its third intracellular loop. Cell Physiol Biochem.
2010;25(4-5):397-408
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Vela C, Diaz-Cabiale Z, Parrado
C, Narvaez M, Covenas R, Narvaez JA. Involvement of oxytocin in the nucleus
tractus solitarii on central cardiovascular control: interactions with
glutamate. J Physiol Pharmacol. 2010 Feb;61(1):59-65.
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Borroto-Escuela DO, Marcellino D,
Narvaez M, Flajolet M, Heintz N, Agnati L, Ciruela F, Fuxe K. A serine point
mutation in the adenosine A2AR C-terminal tail reduces receptor
heteromerization and allosteric modulation of the dopamine D2R. Biochem Biophys
Res Commun. 2010 Mar 26;394(1):222-7
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Borroto-Escuela DO, Narvaez M, Marcellino D, Parrado C, Narvaez JA,
Tarakanov AO, Agnati LF, Díaz-Cabiale Z, Fuxe K. Galanin receptor-1 modulates
5-hydroxtryptamine-1A signaling via heterodimerization. Biochem Biophys Res
Commun. 2010 Mar 19;393(4):767-72.