Spinal Cord & Brain Injury Research Center (SCoBIRC)

Department of Anatomy & Neurobiology

University of Kentucky, USA

Scientist II

Email: Jignesh.Pandya@uky.edu

Qualifications

2002 Ph.D., The Maharaja Sayajirao University of Baroda, Biochemistry

1997 M.S., The Maharaja Sayajirao University of Baroda, Biochemistry

1995 B.S., Gujarat University, Biochemistry

Publications (selected)

1. Avery MA, Rooney TM, Pandya JD, Wishart TM, Gillingwater TH, Geddes JW, Sullivan PG, Freeman MR. Wld (S), Prevents Axon Degeneration through Increased Mitochondrial Flux and Enhanced Mitochondrial Ca (2+) Buffering. Curr Biol. 2012 Mar 14. [Epub ahead of print]. [Impact Factor: 10.881; Citations: 3]
2. Readnower RD, Pandya JD, McEwen ML, Pauly JR, Springer JE, Sullivan PG. Post-Injury Administration of the Mitochondrial Permeability Transition Pore Inhibitor, NIM811, Is Neuroprotective and Improves Cognition after Traumatic Brain Injury in Rats.J Neurotrauma. 2011 Sep; 28 (9): 1845-53. [Impact Factor: 3.654; Citations: 0]
3. Sauerbeck A, Pandya, J, Singh I, Bittman K, Readnower R, Bing G, Sullivan P. Analysis of regional brain mitochondrial bioenergetics and susceptibility to mitochondrial inhibition utilizing a microplate based system. J. Neuroscience Methods. 2011 Mar 15, 198 (1): 36-43. [Impact Factor: 1.980; Citations: 6]
4. Pandya JD, Sullivan PG, Pettigrew LC. Focal cerebral ischemia and mitochondrial dysfunction in the TNFα-transgenic rat. Brain Res. 2011 Apr 12; 1384: 151-60. [Impact Factor: 2.728; Citations: 1]
5. Akundi RS, Huang Z, Eason J, Pandya JD, Zhi L, Cass WA, Sullivan PG, Büeler H. Increased mitochondrial calcium sensitivity and abnormal expression of innate immunity genes precede dopaminergic defects in Pink1-deficient mice. PLoS One. 2011 Jan 13; 6 (1): e16038. [Impact Factor: 4.411; Citations: 11]
6. Srinivasan M, Choi CS, Ghoshal P, Pliss L, Pandya JD, Hill D, Cline G, Patel MS. ß-Cell-specific pyruvate dehydrogenase deficiency impairs glucose-stimulated insulin secretion. Am J Physiol Endocrinol Metab. 2010 Dec; 299 (6): E910-7. [Impact Factor: 4.746; Citations:4]
7. Blalock EM, Grondin R, Chen KC, Thibault O, Thibault V, Pandya JD, Dowling A, Zhang Z, Sullivan P, Porter NM, Landfield PW. Aging-related gene expression in hippocampus proper compared with dentate gyrus is selectively associated with metabolic syndrome variables in rhesus monkeys. J. Neurosci. 2010 Apr 28; 30 (17): 6058-71. [Impact Factor: 7.178; Citations: 18]
8. Liu M, Choi DY, Hunter RL, Pandya JD, Cass WA, Sullivan PG, Kim HC, Gash DM, Bing G. Trichloroethylene induces dopaminergic neurodegeneration in Fisher 344 rats. J. Neurochem. 2010 Feb; 112 (3): 773-83. [Impact Factor: 4.337; Citations:13]
9. Pandya JD, Pauly JR, Sullivan PG. The optimal dosage and window of opportunity to maintain mitochondrial homeostasis following traumatic brain injury using the uncoupler FCCP. Exp Neurol. 2009 Aug; 218 (2): 381-9. [Impact Factor: 4.699; Citations:12]
10. Choi DY, Liu M, Hunter RL, Cass WA, Pandya JD, Sullivan PG, Shin EJ, Kim HC, Gash DM, Bing G. Striatal neuroinflammation promotes Parkinsonism in rats. PLoS One. 2009; 4 (5): e5482. [Impact Factor: 4.411; Citations: 17]
11. Patel SP, Sullivan PG, Pandya JD, Rabchevsky AG. Differential effects of the mitochondrial uncoupling agent, 2, 4-dinitrophenol, or the nitroxide antioxidant, Tempol, on synaptic or nonsynaptic mitochondria after spinal cord injury. J Neurosci Res. 2009 Jan; 87 (1): 130-40. [Impact Factor: 2.99; Citations: 11]
12. Gash DM, Rutland K, Hudson NL, Sullivan PG, Bing G, Cass WA, Pandya JD, Liu M, Choi DY, Hunter RL, Gerhardt GA, Smith CD, Slevin JT, Prince TS. Trichloroethylene: Parkinsonism and complex 1 mitochondrial neurotoxicity. Ann Neurol. 2008 Feb; 63 (2): 184-92. [Impact Factor: 11.089; Citations: 52]
13. Sullivan PG, Krishnamurthy S, Patel SP, Pandya JD, Rabchevsky AG. Temporal characterization of mitochondrial bioenergetics after spinal cord injury. J Neurotrauma. 2007 Jun; 24 (6): 991-9. [Impact Factor: 3.654; Citations: 30]
14. Pandya JD, Agarwal NA, Katyare SS. Dexamethasone treatment differentially affects the oxidative energy metabolism of rat brain mitochondria in developing and adult animals. Int J Dev Neurosci. 2007 Aug; 25 (5): 309-16. [Impact Factor: 2.418; Citations:3]
15. Pandya JD, Pauly JR, Nukala VN, Sebastian AH, Day KM, Korde AS, Maragos WF, Hall ED, Sullivan PG. Post-Injury Administration of Mitochondrial Uncouplers Increases Tissue Sparing and Improves Behavioral Outcome following Traumatic Brain Injury in Rodents. J Neurotrauma. 2007 May; 24 (5): 798-811. [Impact Factor: 3.654; Citations:36]
16. Opii WO, Nukala VN, Sultana R, Pandya JD, Day KM, Merchant ML, Klein JB, Sullivan PG, Butterfield DA. Proteomic identification of oxidized mitochondrial proteins following experimental traumatic brain injury. J Neurotrauma. 2007 May; 24 (5): 772-89. [Impact Factor: 3.654; Citations: 67]
17. Srinivasan M, Katewa SD, Palaniyappan A, Pandya JD, Patel MS. Maternal high-fat diet consumption results in fetal malprogramming predisposing to the onset of metabolic syndrome-like phenotype in adulthood. Am J Physiol Endocrinol Metab. 2006 Oct; 291 (4): E792-9. [Impact Factor: 4.746; Citations: 88]
18. Srinivasan M, Aalinkeel R, Song F, Mitrani P, Pandya JD, Strutt B, Hill DJ, Patel MS. Maternal hyperinsulinemia predisposes rat fetuses for hyperinsulinemia, and adult-onset obesity and maternal mild food restriction reverses this phenotype. Am J Physiol Endocrinol Metab. 2006 Jan; 290 (1): E129-E134. [Impact Factor: 4.746; Citations: 47]
19. Katyare SS, Pandya JD. Modified fluorimetric method for corticosterone estimation and its application for measurement of corticosterone content in rat serum tissues and mitochondria. Ind J Biochem Biophys. 2005 Dec; 42: 48-53. [Impact Factor: 1.142; Citations:5]
20. Katewa SD, Patel BD, Pandya JD, Katyare SS. Lysosomal membrane stabilizing effect of antimalarials –An invitro study. Jr Ani Morphol Physiol. (2003) May; 50: 71-75.
21. Pandya JD, Agarwal NA, Katyare SS. Effect of dexamethasone treatment on oxidative energy metabolism in rat liver mitochondria during postnatal developmental periods. Drug Chem Toxicol. 2004 Nov; 27 (4): 389-403. [Impact Factor: 1.324; Citations: 9]
22. Pandya JD, Patel BD, Katewa SD, Katyare SS. Studies on kinetic properties of acid phosphatase from nuclei-free rat liver homogenate using different substrates. Indian J Exp Biol. 2003 Mar; 41 (3): 205-10. [Impact Factor: 1.295; Citations:1]
23. Pandya JD, Dave KR, Katyare SS. Effect of long-term aluminum feeding on lipid/phospholipid profiles of rat brain myelin. Lipids Health Dis. 2004 Jun 22; 3: 13. [Impact Factor: 2.17; Citations: 23]
24. Pandya JD, Dave KR, Katyare SS. Effect of long-term aluminum feeding on lipid/phospholipid profiles of rat brain synaptic plasma membranes and microsomes. J Alzheimers Dis. 2001 Dec; 3 (6): 531-539. [Impact Factor: 3.745; Citations:13]