Dr. Ashkan Emadi
University of Maryland, USA
Email: aemadi@umm.edu
Qualifications
2004 Ph.D., Illinois Institute
of Technology, Chemistry
1996 M.D., Tehran University of
Medical Sciences, Medicine
Publications (selected)
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Emadi A, Pakbaz Z, Koorosdari H,
Farhadi M, Pasalar P, Malekpoor H, Fayazmoghaddam K. Results of screening
program forb-thalassemia trait on 8500 high school students in Tehran. Iran
Thalassemia Association Journal. 1997; 12: 53-55.
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Pakbaz Z,Emadi A, Moghaddam KF,
Farhadi M, Malekpoor H, Pasalar P. Assessing the level of knowledge in high
school students in Tehran about thalassaemia and the evaluation of an
educational program. Thalassemia International Federation News. 1999; 28(11):
15-17.
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Emadi A, Harwood JS, Kohanim S,
Stagliano KW. Regiocontrolled Synthesis of the Trimeric Quinone Framework of
Conocurvone. Organic Letters.2002;4(4): 521-524.
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Stagliano KW, Lu Z,Emadi A, Harwood
JS, Harwood CA. Effect of Methoxyl Group Position on the Regioselectivity of
Ammonia Substitution Reactions Involving
3,3'-Dichloro-2,2'-binaphthoquinones.Journal of Organic Chemistry. 2004;
69(15): 5128-5131.
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Stagliano KW, Emadi A*, Lu Z,
Malinakova HC, Twenter B, Yu M, Holland LE, Rom AM, Harwood JS, Amin R, Johnson
AA, Pommier Y. Regiocontrolled synthesis and HIV inhibitory activity of
unsymmetrical binaphthoquinone and trimeric naphthoquinone derivatives of
conocurvone. Bioorganic and Medicinal Chemistry. 2006; 14(16): 5651-5665.
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Emadi A, Burns KH, Confer B, Borowitz
MJ, Streiff MB. Hematological manifestations of nephropathic cystinosis.Acta
Haematologica. 2008;119 (3): 169-172.
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Segal JB, Brotman DJ, Necochea
AJ,Emadi A, Samal L, Wilson LM, Crim MT, Bass EB. The Predictive Value of
Factor V Leiden and Prothrombin G20210A in Adults with Venous Thromboembolism
and in Family Members of Those with a Mutation: A Systematic Review of the
Literature. JAMA. 2009; 301(23): 2472-2485.
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Emadi A, Spivak JL. Anagrelide: 20
years later.Expert Review of Anticancer Therapy. 2009; 9(1): 37-50.
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Emadi A, Brodsky RA. Successful
discontinuation of anticoagulation following eculizumab administration in
paroxysmal nocturnal hemoglobinuria.American Journal of Hematology. 2009;
84(10): 699-701.
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Emadi A, Jones RJ, Brodsky RA. Cyclophosphamide
and Cancer: Golden Anniversary. Nature Reviews Clinical Oncology. 2009; 6(11):
638-647.
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Emadi A, Crim MT, Brotman DJ, Necochea
AJ, Samal L, Wilson LM, Bass EB, Segal JB. Analytic Validity of Genetic Tests
to Identify Factor V Leiden and Prothrombin G20210A.American Journal of
Hematology.2010; 85(4): 264-270.
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Antonarakis ES,Emadi A.
Ruthenium-based Chemotherapeutics: Are they ready for prime time?Cancer
Chemotherapy and Pharmacology.2010; 66(1): 1-9.
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Emadi A, Ross AE, Cowan KM, Fortenberry
YM, Vuica-Ross M. A Chemical Genetic Screen for Modulators of Asymmetrical
2,2´-Dimeric Naphthoquinone Cytotoxicity in Yeast.PLoS One. 2010May 26;
5(5):e10846.
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Emadi A, Gore SD. Arsenic trioxide -
An old drug rediscovered.Blood Review. 2010;24(4-5):191-199.
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Ross AE,Emadi A, Marchionni L, Hurley
PJ, Simons BW, Schaeffer EM, Vuica-Ross M. Dimeric naphthoquinones represent a
novel class of compounds with prostate cancer cytotoxicity. British Journal of
Urology International. 2011; 108(3): 447-454.
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Emadi A, Streiff MB. Diagnosis and
Management of Venous Thromboembolism: An Update A Decade into the New
Millennium. Archives of Iranian Medicine.2011; 14 (5): 341-351.
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Emadi A, Streiff MB. Management of
Acquired Thrombophilic Disorders in 2011: Focus on Heparin-induced
Thrombocytopenia, Antiphospholipid Syndrome, Myeloproliferative Neoplasms, and
Paroxysmal Nocturnal Hemoglobinuria. Archives of Iranian Medicine.2011; 14 (6):
401-411.
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Emadi A, Le A, Harwood CA, Stagliano
KW, Kamangar F, Ross AE, Cooper CR, Dang CV, Karp JE, Vuica-Ross
M. Metabolic and Electrochemical Mechanisms ofDimeric Naphthoquinones
Cytotoxicity in Breast Cancer Cells.Bioorganic and Medicinal Chemistry. 2011;
19(23): 7057-7062.
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Kamangar F,Emadi A. Vitamin and
Mineral Supplements: Do We Really Need Them? International Journal of
Preventive of Medicine. 2012; 3: 221-6.
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Emadi A, Karp JE.The Clinically
Relevant Pharmacogenomic Changes in Acute Myelogenous Leukemia. Pharmacogenomics.
(in press)