Prof. Olivier Renaudet

Department of Molecular Chemistry

University of Grenoble, France

Email: olivier.renaudet@ujf-grenoble.fr

 

Qualifications

 

2011 Habilitation à Diriger des Recherches, University Joseph Fourier, Grenoble-I, France

2002 PhD, bioorganic chemistry, University of Grenoble, France

 

Publications (Selected)

1. G. C. Daskhan, N. Berthet, B. Thomas, M. Fiore, O. Renaudet. Multivalent glycocyclopeptides: toward nano-sized glycostructures. Carbohydr. Res., 2015, 405, 13-22. Glyconanomaterials themed issue.
2. B. Thomas, M. Fiore, G. C. Daskhan, N. Spinelli, O. Renaudet. A multi-ligation strategy for the synthesis of heterofunctionalized glycosylated scaffolds. Chem. Commun., 2015, 51, 5436-5439. ChemComm Emerging Investigators Issue 2015.
3. D. Thakar, E. Migliorini, L. Coche-Guérente, R. Sadir, H. Lortat-Jacob, D. Boturyn, O. Renaudet, P. Labbé, R. P. Richter. A quartz crystal microbalance method to study the terminal functionalization of glycosaminoglycans. Chem. Commun., 2014, 50, 15148-15151.
4. C. Nativi, O. Renaudet. Recent progress in antitumoral synthetic vaccines. ACS Med. Chem. Lett., 2014, 5, 1176-1178. Viewpoint.
5. B. Richichi, B. Thomas, M. Fiore, R. Bosco, H. Qureshi, C. Nativi, O. Renaudet, L. BenMohamed. A cancer therapeutic vaccine based on clustered Tn-antigen mimetics induces strong antibody-mediated protective immunity. Angew. Chem. Int. Ed., 2014, 53, 11917-11920.
6. K. Křenek, R. Gažák, G. C. Daskhan, J. Garcia, M. Fiore, P. Dumy, M. Šulc, V. Křen, O. Renaudet. Access to bifunctionalized biomolecular platforms using oxime ligation. Carbohydr. Res., 2014, 393, 9-14.
7. M. Fiore, N. Berthet, O. Renaudet, V. Barbier. New glycopolymers as multivalent systems for lectin recognition. Med. Chem. Commun., 2014, 5, 1202-1207.
8. M. Ghirardello, K. Öberg, S. Staderini, O. Renaudet, N. Berthet, P. Dumy, Y. Hed, A. Marra, M. Malkoch, A. Dondoni. Thiol-ene and thiol-yne based synthesis of glycodendrimers as nanomolar inhibitors of wheat germ agglutinin. J. Polym. Sci., Part A: Polym. Chem., 2014, 52, 2422-2433.
9. S. Ulrich, D. Boturyn, A. Marra, O. Renaudet, P. Dumy. Oxime-bond ligation: a chemoselective click-type reaction for accessing multifunctional biomolecular constructs. Chem. Eur. J., 2014, 20, 34-41.
10. D. Rozbeský, J. Krejzová, K. Křenek, J. Prchal, R. Hrabal, M. Kožíšek, L. Weignerová, M. Fiore, P. Dumy, O. Renaudet, V. Kren. Reevaluation of binding properties of recombinant lymphocyte receptors NKR-P1A and CD69 to chemically synthesized glycans and peptides. Int. J. Mol. Sci., 2014, 15, 1271-1283.
11. S. Ulrich, D. Boturyn, A. Marra, O. Renaudet, P. Dumy. Oxime-bond ligation: a chemoselective click-type reaction for accessing multifunctional biomolecular constructs. Chem. Eur. J., 2014, 20, 34-41.
12. B. Thomas, N. Berthet, J. Garcia, P. Dumy, O. Renaudet. Expanding the scope of oxime ligation: facile synthesis of large cyclopeptide-based glycodendrimers. Chem. Commun., 2013, 49, 10796-10798.
13. N. Berthet, B. Thomas, I. Bossu, E. Dufour, E. Gillon, J. Garcia, N. Spinelli, A. Imberty, P. Dumy, O. Renaudet. High affinity glycodendrimers for the lectin LecB from Pseudomonas aeruginosa. Bioconjugate Chem., 2013, 24, 1598-1611.
14. M. Fiore, N. Berthet, A. Marra, E. Gillon, P. Dumy, A. Dondoni, A. Imberty, O. Renaudet. Tetravalent glycocyclopeptide with nanomolar affinity to wheat germ agglutinin. Org. Biomol. Chem., 2013, 11, 7113-7122.
15. O. Renaudet, R. Roy. Multivalent scaffolds in glycoscience: an overview. Chem. Soc. Rev., 2013, 42, 4515-4517. Editorial for Themed Issue on Multivalent Scaffolds in Glycosciences.
16. M. C. Galan, P. Dumy, O. Renaudet. Multivalent glycol(cyclo)peptides. Chem. Soc. Rev., 2013, 42, 4599-4612.
17. A. Bernardi, J. Jiménez-Barbero, A. Casnati, C. De Castro, T. Darbre, F. Fieschi, J. Finne, H. Funken, K.-E. Jaeger, M. Lahmann, T. K. Lindhorst, M. Marradi, P. Messner, A. Molinaro, P. Murphy, C. Nativi, S. Oscarson, S. Penadés, F. Peri, R. J. Pieters, O. Renaudet, J.-L. Reymond, B. Richichi, J. Rojo, F. Sansone, C. Schäffer, W. B. Turnbull, T. Velasco-Torrijos, S. Vidal, S. Vincent, T. Wennekes, H. Zuilhof, A. Imberty. Multivalent glycoconjugates as anti-pathogenic agents. Chem. Soc. Rev., 2013, 42, 4709-4727.
18. A. Marra, S. Staderini, N. Berthet, P. Dumy, O. Renaudet, A. Dondoni. Thiyl glycosylation of propargylated octasilsesquioxane: synthesis and lectin binding properties of densely glycosylated clusters on a cubic platform. Eur. J. Org. Chem., 2013, 1144-1149.
19. M. Fiore, B. Thomas, V. Duléry, P. Dumy, O. Renaudet. Synthesis of multi-antigenic platforms as vaccine candidates against cancers. New J. Chem., 2013, 37, 286-289.
20. S. Ulrich, P. Dumy, D. Boturyn, O. Renaudet. Engineering of biomolecules for sensing and imaging applications. J. Drug Deliv. Sci. Tech., 2013, 23, 5-15. Special Issue on Imaging.
21. B. Thomas, M. Fiore, I. Bossu, P. Dumy, O. Renaudet. Synthesis of heteroglycoclusters using orthogonal chemoselective ligations. Beilstein J. Org. Chem., 2012, 8, 421-427.
22. M. Lo Conte, S. Staderini, A. Chambery, N. Berthet, P. Dumy, O. Renaudet, A. Marra, A. Dondoni. Glycoside and peptide clustering around the octasilsesquioxane scaffold via photoinduced free-radical thiol-ene coupling. The observation of a striking glycoside cluster effect. Org. Biomol. Chem., 2012, 10, 3269-3277.
23. I. Bossu, N. Berthet, P. Dumy, O. Renaudet. Synthesis of glycocyclopeptides by click chemistry and inhibition assays with lectins. J. Carbohydr. Chem., 2011, 30, 458-468.
24. S. André, O. Renaudet, I. Bossu, P. Dumy, H.-J. Gabius. Cyclic glycodecapeptides: how to increase their inhibitory activity and selectivity on lectin/toxin binding to a glycoprotein and cells. J. Pept. Sci., 2011, 17, 427-437.
25. I. Bossu, M. Šulc, K. Křenek, E. Dufour, J. Garcia, N. Berthet, P. Dumy, V. Křen, O. Renaudet. Dendri-RAFTs: a second generation of cyclopeptide-based glycoclusters. Org. Biomol. Chem., 2011, 9, 1948-1959.
26. M. Galibert, O. Renaudet, P. Dumy, D. Boturyn. Access to biomolecular assemblies via one-pot triple orthogonal chemoselective ligations. Angew. Chem. Int. Ed., 2011, 50, 1901-1904.
27. A. Pujol, M. Cuillel, O. Renaudet, C. Lebrun, P. Charbonnier, D. Cassio, C. Gateau, P. Dumy, E. Mintz, P. Delangle. Hepatocyte targeting and intracellular copper chelation by a thiol-containing glycocyclopeptide. J. Am. Chem. Soc., 2011, 133, 286-296.
28. O. Renaudet, C. Philouze, C. Bailly, A. Durif, P. Dumy. X-ray structure of the key synthetic intermediate of a cancer-related sialyl-Tn antigen analogue. J. Chem. Crystallog., 2011, 41, 204-208.
29. M. Galibert, L. Sancey, O. Renaudet, J.-L. Coll, P. Dumy, D. Boturyn. Application of click-click chemistry to the synthesis of new multivalent RGD conjugates. Org. Biomol. Chem., 2010, 8, 5133-5138.
30. O. Renaudet, G. Dasgupta, I. Bettahi, A. Shi, A. B. Nesburn, P. Dumy, L. BenMohamed. Linear and branched glyco-lipopeptides vaccines follow distinct cross-presentation pathways and generate different magnitudes of antitumor immunity. PLoS ONE, 2010, 5, e11216.