Dr. Raj K. Batra
David Geffen School of Medicine
UCLA, USA
Email: rbatra@ucla.edu
Qualifications
1988 M.D., University of Toledo College of Medicine & Life
Sciences
1983 B.Sc., Ohio State University
Publications (selected)
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Batra RK, S. Oh and SK Basak. The isolation and molecular
characterization of cancer stem cells (aggressive endophenotypes) in individual
lung cancers. In Stem Cells, Tissue Engineering and
Regenerative Medicine. Edited by David Warburton. Imperial College Press,
London, UK 2014.
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Veena MS, R Wilken, JY Zheng, A Gholkar, D Vira, S Ahmed, SK Basak, RK
Batra, N Kasahara, D Elashoff , MC Fishbein, JP Whitelegge, JZ Torres, MB Wang,
ES Srivatsan. p16 recruits gigaxonin for NFκB ubiquitination in cisplatin
induced senescence. J Biol Chem. 2014, Dec 12;
289(50):34921-37. [Epub ahead of print Oct 20]. (PMID: 25331947).
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Basak SK, MS Veena, S Oh, C Lai, S Vangala, D
Elashoff , MC Fishbein, S Sharma, NP Rao, D Rao, R Phan,
ES Srivatsan, and RK Batra. The CD44high tumorigenic
subsets in lung cancer biospecimens are enriched for low miR-34a
expression. PLoS One. 2013 Sep 3; 8(9): e73195. (PMC: 3790883).
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Batra RK, Soo Hoo GW. Reprogrammed cells for respiratory
papillomatosis (Letter). N Engl J Med. 2012, Dec 27; 367(26): 2553-4. (PMID: 23268676).
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Darshni Vira, SK. Basak, MS. Veena, MB. ang, RK. Batra*, and
ES Srivatsan,* Cancer stem cells, microRNAs, and
therapeutic strategies, including natural products. Cancer and
Metastases Reviews. (*Co-corresponding author). 2012 Dec;
31(3-4): 733-51. (PMID: 22752409).
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Frey MR, Carraro G, Batra RK, Polk DB, Warburton D. Sprouty
keeps bowel kinases regular in colon cancer, while miR-21 targets
Sprouty. Cancer Biol Ther. 2011 Jan 1; 11(1): 112-114. (PMID:
21124074).
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Batra RK and D Warburton. On the derivation and clinical
implications of “driver” mutations in lung cancer. Am J Resp. and
Critical Care Med. 2010 July (182). pp. 4-5, (Invited Editorial). (PMID: 20463175).
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Limsukon A, I Susanto, G Soo Hoo, SM Dubinett, and RK Batra. Regression of recurrent respiratory papillomatosis with celecoxib and erlotinib
combination therapy CHEST 2009 Sept. (136): 924-926. (PMID:
19736197).
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Veena MS, M Qin, A Andersson, S Sharma, and RK Batra. CAR
mediates efficient tumor engraftment of mesenchymal type lung cancer
cells. Lab. Invest. 2009 Aug; 89(8): 875-86. (PMID:
19506548).
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Basak SK, MS Veena, S Oh, G Huang, E Srivatsan, M Huang, S Sharma, and RK
Batra. The malignant pleural effusion as a model to investigate
intratumoral heterogeneity in lung cancer. PLoS ONE. 2009, Jun
12; 4(6): e5884. (PMC: 2697051).
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Andersson A, SC Yang, M Huang, L Zhu, UK Kar, RK Batra, D Elashoff, RM
Strieter, SM Dubinett, and S Sharma. IL-7 Promotes CXCR3 Ligand-Dependent T
Cell Antitumor Reactivity in Lung Cancer. J Immunol. 2009 Jun 1;
182(11): 6951-8.
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Baratelli F, H Takedatsu, S Hazra, K Peebles, J Luo, PS Kurimoto, G
Zeng, RK Batra, S Sharma, SM Dubinett, JM Lee. Pre-clinical characterization of
GMP grade CCL21-gene modified dendritic cells for application in a phase I
trial in Non- Small Cell Lung Cancer. J Translational Med. 2008 Jul 22;
6(1): 38. (PMC: 2507704).
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Hazra S, RK Batra, HH Tai, S Sharma S, X Cui, SM Dubinett. Pioglitazone
and Rosiglitazone decrease PGE2 in non-small cell lung cancer cells by upregulating
15-hydroxyprostaglandin dehydrogenase. Mol Pharmacol. 2007 Jun; 71(6): 1715-20.
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Dohadwala M, SC Yang, J Luo, S Sharma, RK Batra, M Huang, Y Lin, L
Goodglick, K Krysan, MC Fishbein, L Hong, C Lai, RB Cameron, RM Gemmill, HA
Drabkin, SM Dubinett. Cyclooxygenase-2- Dependent Regulation of E-Cadherin:
Prostaglandin E2 Induces Transcriptional Repressors ZEB1 and Snail in Non-Small
Cell Lung Cancer. Cancer Res. 2006 May 15; 66(10): 5338-45.
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Hillinger S, SC Yang, RK Batra, RM Strieter, W Weder, SM Dubinett, S
Sharma. CCL19 reduces tumor burden in a model of advanced lung cancer. Br J
Cancer. 2006 Apr 10; 94(7): 1029-34. (PMC: 2361223).
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Yang SC, RK Batra, S Hillinger, KL Reckamp, RM. Strieter, SM. Dubinett,
and S Sharma. Intrapulmonary Administration of CCL21 Gene-Modified Dendritic
Cells Reduces Tumor Burden in Spontaneous Murine Bronchoalveolar Cell
Carcinoma. Cancer Res. 2006, 66: 3205-3213.