Guoqiang Yu

University of Kentucky, USA

Email: guoqiang.yu@uky.edu

Qualifications

1999     Ph.D. in Biomedical Engineering, Tianjin University, Tianjin, China.

1989     Master in Biomedical Engineering, Tianjin University, Tianjin, China.

1986     Bachellor in Biomedical Engineering, Tianjin University, Tianjin, China.

Publications (Selected)

1. K. Gurley, Y. Shang, G. Yu, “Noninvasive optical quantification of absolute blood flow, blood oxygenation, and oxygen consumption rate in exercising skeletal muscle,” Journal of Biomedical Optics 17, 075010 (2012)
2. R. Cheng, Y. Shang, D. Hayes, S. Saha, G. Yu, “Noninvasive optical evaluation of spontaneous low frequency oscillations in cerebral hemodynamics,” NeuroImage 62(3), 1445-1454(2012)
3. L. Dong, M. Kudrimoti,R. Cheng, Y. Shang, E. L. Johnson,
   S. D. Stevens, B. J. Shelton, G. Yu, “Noninvasive diffuse optical monitoring of head and neck tumor blood flow and oxygenation during radiation delivery,” Biomedical Optics Express 3, 259-272 (2012) (highlighted as spotlight paper)
4. Y. Lin,L. He, Y. Shang, G. Yu, “Noncontact diffuse correlation spectroscopy for noninvasive deep tissue blood flow measurement,” Journal of Biomedical Optics Letters 17(2), 010502 (2012)
5. N. Munk, B. Symons, Y. Shang, R. Cheng, G. Yu, “Noninvasively measuring the hemodynamic effects of massage on skeletal muscle: a novel hybrid near-Infrared diffuse optical instrument,” Journal of Bodywork & Movement Therapies 16(1), 22-28 (2012)
6. G. Yu, “Near-infrared diffuse correlation spectroscopy (DCS) in cancer diagnosis and therapy monitoring,” Journal of Biomedical Optic 17(2), Invited review, 010901 (2012)
7. G. Yu, “Diffuse correlation spectroscopy (DCS): a diagnostic tool for assessing tissue blood flow in vascular-related diseases and therapies,” Current Medical Imaging Reviews, Invited review, Volume 8, 4 Issues (2012)
8. G. Yu, "Near-infrared diffuse correlation spectroscopy (DCS) for assessing deep tissue blood flow", Invited review, Anatomy and Physiology 2(2) 1000e115 (2012)
9. L. Chen, Y. Shang, E. Sipos, K. E. Saatman, G. Yu, M Toborek, “Novel experimental model for repeated forebrain ischemia-reperfusion,” Journal of experimental stroke and translational medicine, Vol. 5, No. 1, pp. 1-10 (2012)
10. A. L. Maas, S. L. Carter, E. P. Wileyto, J. Miller, M. Yuan, G. Yu, A. Durham, T. M. Busch, “The tumor vascular microenvironment determines responsiveness to photodynamic therapy,” Cancer Research 72(8): 2079-88 (2012)
11. Y. Shang, L. Chen, M Toborek, G. Yu, ^“Diffuse optical monitoring of repeated cerebral ischemia in mice,” Optics Express19, 20301-20315 (2011) (highlighted by Virtual Journal for Biomedical Optics)
12. D. Irwin, L. Dong, Y. Shang, R. Cheng, M. Kudrimoti, S. D. Stevens, G. Yu, "Influences of tissue absorption and scattering on diffuse correlation spectroscopy blood flow measurements," Biomedical Optics Express 2, 1969–1985 (2011)
13. Y. Shang, R. Cheng, L. Dong, S. J. Ryan, S. P. Saha, G. Yu, “Cerebral monitoring during carotid endarterectomy using near-infrared diffuse optical spectroscopies and electroencephalogram,” Physics in Medicine and Biology 56, 3015–3032 (2011)
14. G. Yu, Y. Shang, Y. Zhao, R. Cheng, L. Dong, S. P. Saha, “Intraoperative Evaluation of Revascularization Effect on Ischemic Muscle Hemodynamics Using Near-infrared Diffuse Optical Spectroscopies,” Journal of Biomedical Optics 16(2), 027004 (2011) (highlighted by Virtual Journal of Biological Physics Research)
15. R. C. Mesquita, T. Durduran, G. Yu, E. M. Buckley, M. N. Kim, C. Zhou, R. Choe, U. Sunar, A. G. Yodh, “Direct measurement of tissue blood flow & metabolism with diffuse optics," Phil. Trans. R. Soc. A 369, 4390–4406, doi:10.1098/rsta.2011.0232 (2011)
16. Y. Shang, T. B. Symons, T. Durduran, A. G. Yodh, G. Yu, "Effects of muscle fiber motion on diffuse correlation spectroscopy blood flow measurements during exercise," Biomedical Optics Express 1, 500-511 (2010)
17. T. M. Busch, H. W. Wang, E. P Wileyto, G. Yu, R. M. Bunte, “Increasing damage to tumor blood vessels during vascular-targeting PDT through use of low fluence rate,” Radiation Research 0033-7587/10 (2010)
18. T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, W. J. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, D. J. Licht. “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” Journal of Biomedical Optics 15(3):037004 (2010)
19. M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, W. A. Kofke, "Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared diffuse correlation spectroscopies in critically brain-injured adults," Neurocrit Care 12(2): 173-180 (2010)
20. Y. Shang, Y. Zhao, R. Cheng, L. Dong, D. Irwin, G. Yu, “Portable optical tissue flow oximeter based on diffuse correlation spectroscopy,” Optics Letters 34(22), 3556-3558 (2009) (highlighted by Virtual Journal of Biological Physics Research)
21. T. M. Busch, X. Xing, G. Yu, A. G. Yodh, E. P. Wileyto, H. W. Wang, T. Durduran, T. C. Zhu, K. K.H. Wang, “Fluence rate-dependent intratumor heterogeneity in physiologic and cytotoxic responses to photofrin photodynamic therapy,” Photochemistry & Photobiology Science 8: 1683-1693 (2009)
22. C. Zhou, S. A. Eucker,T. Durduran,G. Yu,J. Ralston, S. H. Friess,R. N. Ichord,S. S. Margulies,and A. G. Yodh, “Diffuse optical monitoring of hemodynamic changes in piglet brain with closed head injury,” Journal of Biomedical Optics 14(3):034015 (2009)
23. T. Durduran, C. Zhou, L. E. Brian, G. Yu, R. Choe, M. N. Kim, B. L. Cucchiara, M. E. Putt, Q. Shah, S. E. Kasner, J. H. Greenberg, A. G. Yodh, J. A. Detre, "Transcranial optical monitoring of cerebral blood flow and hemoglobin concentration in acute stroke patients during positional interventions," Annals of Neurology, Optics Express 17(5):3884-3902 (2009)
24. M. Buckley, N. M. Cook, T. Durduran, M. N. Kim, C. Zhou, R. Choe, G. Yu, S. Schultz, C. M. Sehgal, D. J. Licht, P. H. Arger, M. E. Putt, H. H. Hurt, A. G. Yodh. “Cerebral hemodynamics in preterm infants during positional intervention measured with diffuse correlation spectroscopy and transcranial doppler ultrasound,” Optics Express, 17(15):12571-12581 (2009)
25. C. Zhou, T. Shimazu, T. Durduran, J. Luckl, D. Y. Kimberg, G. Yu, X. H. Chen, J. A. Detre, A. G. Yodh, J. H. Greenberg, "Acute functional recovery of cerebral blood flow after forebrain ischemia in rat," Journal of Cerebral Blood Flow & Metabolism 28(7), 1275-1284 (2008)
26. G. Yu, T. F. Floyd, T. Durduran, C. Zhou, J. A. Detre, A. G. Yodh, “Diffuse Correlation Spectroscopy for Muscle Blood Flow: Validation with Arterial-Spin-Labeling Perfusion MRI,” Optics Express, 15:1064-1075, 2007
27. U. Sunar, S. Makonnen, C. Zhou, T. Durduran, G. Yu, H. W. Wang, W. M. Lee, A. G. Yodh, "Hemodynamic responses to antivascular therapy and ionizing radiation assessed by diffuse optical spectroscopies," Optics Express 15(23), 15507-15516 (2007)
28. C. Zhou, R. Choe, N. Shah, T. Durduran, G. Yu, A. Durkin, D. Hsiang, R. Mehta, J. Butler, A. Cerussi, B. J. Tromberg, A. G. Yodh, "Diffuse optical monitoring of blood flow and oxygenation in human breast cancer du ring early stages of neoadjuvant chemotherapy," Journal of Biomedical Optics 12(5), 051903 (2007)
29. C. Zhou, G. Yu, D. Furuya, J. A. Detre, J. H. Greenberg, A. G. Yodh, T. Durduran, "Diffuse optical correlation tomography of cerebral blood flow during cortical spreading depression in rat brain," Optics Express 24(3), 1125-1144 (2006)
30. G. Yu, T. Durduran, C. Zhou, T. C. Zhu, J. C. Finlay, T. M. Busch, S. B. Malkowicz, S. M. Hahn, A. G. Yodh, "Real-time in situ monitoring of human prostate photodynamic therapy with diffuse light," Photochemistry & Photobiology 82(5), 1279-1284 (2006)