Dr. Jean-Claude Lavoie

University of Montreal, Canada

Email: Jean-claude.lavoie@umontreal.ca

Qualifications

1998 Ph.D., Biomedical Sciences, University of Montreal, Canada

1992 M.Sc., Biomedical Sciences, University of Montreal, Canada

1989 Diploma, Graduate Study Diploma Specialized in Toxicology, University of Montreal, Canada

1983 Diploma, Undergraduate Certificate in Environmental Sciences, Université du Québec à Montréal, Canada

1976 B.Sc., Biochemical, University of Montreal, Canada

Publications(Selected)

1. Harrison A, Khashu M, Friel J, Lavoie JC, Chessex P. Variations in metabolic response to TPN are influenced more by gender than light exposure. J Pediatr Gastroenterol Nutr 45:577-581, 2007
2. Chessex P, Harrison A, Khashu M, Lavoie JC. In preterm neonates, is the risk of developing bronchopulmonary dysplasia influenced by the failure to protect total parenteral nutrition from exposure to ambient light? J Pediatr 151:213-214, 2007
3. Levy E, Trudel K, Bendayan M, Seidman EG, Delvin E, Elchebly M, Lavoie JC, Precourt LP, Amre D, Sinnett D. Biological role, Protein Expression, Subcellular Localization and Oxidative Stress Response of Paraoxonase2 in the Intestine of Humans and Rats. Am J Physiol Gastrointest Liver Physiol. 293:G1252-61, 2007
4. Yang C, Mwaikambo RB, Zhu T, Gagnon C, Seshadri S, Lachapelle P, Lavoie JC, Chemtob S, Hardy P. Lymphocytic microparticles inhibit angiogenesis by stimulating oxidative stress and negatively regulating VEGFinduced pathways, AJP- Regulatory, Integrative and Comparative Physiology 294:R467-76, 2008
5. Lavoie JC, Rouleau T, Tsopmo A, Friel J, Chessex P. Influence of lung oxidant and antioxidant status on alveolarization: role of light-exposed total parenteral nutrition. Free Radic Biol Med 45:572-577, discussion 570-1, 2008
6. Yzydorczyk C, Comte B, Cambonie G, Lavoie JC, Germain N, Shun YT, Wolff J, Deschepper C, Touyz RM, Lelievre-Pegorier M, Nuyt AM. Neonatal oxygen exposure in rats leads to cardiovascular and renal alterations in adulthood. Hypertension 52:889-95, 2008
7. Khashu M, Harrison A, Lalari V, Lavoie JC, Chessex P. Impact of shielding parenteral nutrition from light on routine monitoring of plasma glucose and triglyceride in preterm neonates. Arch Dis Child Fetal Neonatal 94:F111-5, 2009
8. Turcot V, Nuyt AM, Rouleau T, Tsopmo A, Germain N, Potvin L, Lavoie JC. Long-term impact of a deficient neonatal diet to sustain the antioxidant defence on the lipid and glucose metabolism. Free Radic Biol Med 47 :275-282, 2009
9. Chessex P, Khashu M, Harrison A, Hosking M, Sargent M, Lavoie JC. Early life events, sex and arterial blood pressure in critically ill infants. Pediatric Crit Care Med 11:75-81, 2010
10. Zaniolo K, St-Laurent JF, Gagnon SN, Lavoie JC, Desnoyers S. Photoactivated multivitamin preparation induces poly(ADP-ribosyl)ation, a DNA damage response in mammalian cells. Free Radic Biol Med, 48:1002-12, 2010
11. Maghdessian R, Côté F, Rouleau T, Ouadda ABD, Levy E, Lavoie JC. Ascorbylperoxide contaminating parenteral nutrition perturbs the lipid metabolism in newborn guinea pig. J Pharmacol Exp Ther 334:278-284, 2010
12. Kleiber N, Rouleau T, Nuyt AM, Chessex P, Perreault M, Lavoie JC. Neonatal exposure to oxidants induces later in life a metabolic response associated to a phenotype of energy deficiency in an animal model of TPN. Pediatr Res 68:188-92, 2010
13. Lavoie P, Lavoie JC, Watson C, Rouleau T, Chang BA, Chessex P. Inflammatory response in preterm infants is induced early in life by oxygen and modulated by TPN. Pediatr Res 68:248-51, 2010
14. Chessex P, Watson C, Kaczala G, Rouleau T, Lavoie ME, Friel J, Lavoie JC. Determinants of oxidant stress in extremely low birth weight premature infants. Free Radic Biol Med 49 :1380-6, 2010
15. Précourt LP, Amre D, Denis MC, Lavoie JC, Delvin E, Seidman E, Levy E. The three-gene paraoxonase family: Physiologic roles, actions and regulation. Atherosclerosis. 214(1):20-36, 2010
16. Tsopmo A, Romanowski A, Banda L, Lavoie JC, Jenssen H, Friel J. Novel anti-oxidative peptides from enzymatic digestion of human milk. Food Chem 126 :1138-1143, 2011
17. Marcil V, Lavoie JC, Emonnot L, Seidman E, Levy E. Analysis of the effects of iron and vitamin C cosupplementation on oxidative damage, antioxidant response and inflammation in THP-1 macrophages. Clin Biochem 44 :873-883, 2011
18. Lavoie ME, Ziai S, Rabasa-Lhoret R, Lavoie JC. Blood glutathione peroxidase activity in relation with the risk of cardiovascular diseases in obese woman. J Diabetes Metab 2:136, doi:10.4172/2155-6156.1000136, 2011
19. Lavoie JC, Mohamed I. Bronchopulmonary dysplasia: The role of oxidative stress. In: Lung Diseases – Selected State of the Art Reviews. Ed: Elvis Malcolm Irusen, Publisher : InTech, 22 :485-504, ISBN 978- 953-51-0180-2, 2012
20. Miloudi K, Comte B, Rouleau T, Montoudis A, Levy E, Lavoie JC. The mode of administration of total parenteral nutrition and nature of lipid content influence the generation of peroxides and aldehydes. Clin Nutr, doi:10.1016/j.clnu.2012 Jan 7, 2012