Dr. Yongchao Su
Massachusetts Institute of Technology, USA
Research Fellow
Email: ycsu@mit.edu
Qualifications
2011 Ph.D., Chemistry, Iowa State University, USA
2006 M.Sc., Physics, Chinese Academy of Sciences, China
2003 B.Sc., Chemistry, Huazhong University of Science & Technology, China
2003 B.A., English, Huazhong University of Science & Technology, China
Publications (selected)
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Y. Su, F. Hu and M. Hong, Paramagnetic Cu(II) for Probing Membrane Protein Structure and Function: Inhibition of the influenza M2 Proton Channel, J. Am. Chem. Soc., 2012, 134(20), 8693-8702 (2012)
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S, Li* and Y. Su* (*corresponding authors) and M. Hong, Intra-molecular 1H-13C Distance Measurement in Uniformly 13C, 15N Labeled Peptide by Solid State NMR, Solid State Nucl. Magn. Reson. 45-46, 51-58 (2012)
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Y. Su and M. Hong, “Conformational Disorder of Membrane Peptides Investigated from Solid-State NMR Linewidths and Lineshapes”, J. Phys. Chem. B. 115(36), 10758-10767 (2011)
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M. Hong and Y. Su, “Structure and Dynamics of Cationic Membrane Peptides and Proteins: Insights from Solid-State NMR”, Protein Science, 20(4), 641-655 (2011)
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Y. Su, A. J. Waring, P. Ruchala and M. Hong, “Solid-State NMR Study of β-hairpin Antimicrobial Protegrin Peptides in Lipopolysaccharide Incorporated Lipid Membranes: Mechanism of Gram Selectivity”, Biochemistry, 50(12), 2072-2083 (2010)
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Y. Su, W. F. DeGrado and M. Hong, “Orientation, Dynamics and Lipid Interaction of an Antimicrobial Arylamide Investigated by 19F and 31P Solid-State NMR Spectroscopy”, J. Am. Chem. Soc. 132(26), 9197–9205 (2010)
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T. Doherty*, Y. Su* (*equal contribution) and M. Hong, “High-Resolution Orientation and Depth of Insertion of the Voltage-Sensing S4 Helix of a Potassium Channel in Lipid Bilayers”, J. Mol. Biol. 401(4), 642-652 (2010)
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Y. Su, A. J. Waring, P. Ruchala and M. Hong, “Membrane-Bound Dynamic Structure of an Arginine-Rich Cell-Penetrating Peptide, the Protein Transduction Domain of HIV TAT, from Solid-State NMR”, Biochemistry. 49 (29), 6009–6020 (2010)
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S. Li, Y. Su, W. Luo and M. Hong, “Water-Protein Interactions of an Arginine-Rich Membrane Peptide in Lipid Bilayers Investigated by Solid-State Nuclear Magnetic Resonance Spectroscopy”, J. Phys. Chem. B. 114, 4063–4069 (2010)
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Y. Su, T. Doherty, A. J. Waring, P. Ruchala and M. Hong, “Role of Arginine and Lysine Residues in the Translocation of a Cell-Penetrating Peptide from 13C, 31P and 19F Solid-State NMR”, Biochemistry, 48(21), 4587-4595 (2009).
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Y. Su, R. Mani, T. Doherty, A. J. Waring and M. Hong, “Reversible Sheet – Turn Conformational Change of a Cell-Penetrating Peptide in Lipid Bilayers Studied by Solid-State NMR”, J. Mol. Biol. 381, 1133-1144 (2008).
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Y. Su, R. Mani, and M. Hong, “Asymmetric Insertion of Membrane Proteins in Lipid Bilayers by Solid-State NMR Paramagnetic Relaxation Enhancement: a Cell-Penetrating Peptide Example”, J. Am. Chem. Soc. 130(27), 8856-8864 (2008).
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S. Li, A. Zheng, Y. Su, H. Fang, W. Shen, Z. Yu, L. Chen and F. Deng, “Extra-Framework Aluminum Species in Hydrated Faujasite Zeolite as Investigated by Two-Dimensional Solid-State NMR Spectroscopy and Theoretical Calculations”, Phys. Chem. Chem. Phys. 12(15), 3895-3903 (2010).
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S. Li, A. Zheng, Y. Su, H. Zhang, L. Chen, J. Yang, C. Ye, and F. Deng, “Brønsted/Lewis Acid Synergy in Dealuminated HY Zeolite: A Combined Solid-State NMR and Theoretical Calculation Study”, J. Am. Chem. Soc. 129(36), 11161-1117 (2007).
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J. Wang, Y. Su, J. Xu, C. Ye and F. Deng, “Acid Sites and Oxidation Center in Molybdena Supported on Tin Oxide as Studied by Solid-State NMR Spectroscopy and Theoretical Calculation”, Phys. Chem. Chem. Phys. 8, 2378-2384 (2006).
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W. Hu, Q. Luo, Y. Su, L. Chen, Y. Yue, C. Ye, and F. Deng, “Acid Sites in Mesoporous Al-SBA-15 Material as Revealed by Solid-State NMR Spectroscopy”, Microporous and Mesoporous Mater. 92, 22-30 (2006).
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J. Xu, A. Zheng, J. Yang, Y. Su, J. Wang, D. Zeng, F. Deng, M. Zhang, and C. Ye, “Acidity of Mesoporous MoOx/ZrO2 and WOx/ZrO2 Materials: A Combined Solid-State NMR and Theoretical Calculation Study”, J. Phys. Chem. B. 110(22), 10662-10671 (2006).
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A. Zheng, L. Chen, J. Yang, M. Zhang, Y. Su, Y. Yue, and F. Deng, “Combined DFT Theoretical Calculation and Solid-State NMR Studies of Al Substitution and Acid Sites in Zeolite H-MCM-22”, J. Phys. Chem. B. 109(51), 24273-24279 (2005).
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W. Hu, Y. Su, L. Chen, Y. Yue, S. Li, and F. Deng, “The 27Al State in CeO2-γ-Al2O3 Mixed Oxides Determined by Solid-State NMR Spectroscopy”, Chinese J. Magn. Reson. 24(1), 17-25 (2007)
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Y. Su, A. Zheng, S. Li, L. Chen, and F. Deng, “Quantum Chemical Calculation on 13C NMR Shifts of Small Drug Molecules”, Chinese J. Magn. Reson. 23(3), 293-301 (2006)
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