Prof. Edouard Kouassi

University of Montreal, Canada



1990 Ph.D., University Claude-Bernard, Lyon-1, Pharmaceutical Sciences

1985 Ph.D., University of Montreal, Pharmacology

1982 M.Sc., University Claude-Bernard, Lyon-1, Immunology

1981 M.Sc., University of Montreal, Pharmacology

1979 B.Sc., Pharmacy, University of Montreal

Publications (Selected)

1. McIntyre A, Paisley D, Kouassi E, Gendron A. Quetiapine fumarate extended-release for the treatment of major depression with comorbid fibromyalgiasyndrome: a double-blind, randomized, placebo-controlled study. Arthritis&Rheumatology 66:451-461, 2014.

2. Vincent PD, Kouassi E. Efficacy of antipsychotic drugs for schizophrenia. The Lancet 382:1873-1874, 2013.

3. Tourjman V, Kouassi É, Koué MÈ, Rocchetti M, Fortin-Fournier S, Fusar-Poli P, Potvin S. Antipsychotics' effects on blood levels of cytokines in schizophrenia: a meta-analysis. Schizophrenia Research 151:43-47, . 2013.

4. Desfossés J, Stip E, Bentaleb LA, Lipp O, Chiasson JP, Furtos A, Venne K, Kouassi E, Potvin S. Plasma Endocannabinoid Alterations in Individuals with Substance Use Disorder are Dependent on the "Mirror Effect" of Schizophrenia. Frontiers in Psychiatry 3:85, 2012.

5. Tourjman, SV, Koué, ME, Kouassi, E, Potvin, S. In vivo immunomodulatory effects of antipsychotics on inflammatory mediators: a review. Advances in Bioscience and Biotechnology Vol. 3 No. 4A, 2012.

6. Igue R, Potvin S, Bah R, Stip E, Bouchard RH, Lipp O, Gendron A, Kouassi E. Soluble interleukin-2 receptor levels correlated with positive symptoms during quetiapine treatment in schizophrenia. Progress in Neuro-Psychopharmacology & Biological Psychiatry 35:1695-1698, 2011.

7. Potvin S, Stip E, Sepehry AA, Gendron A, Bah R, Kouassi E. Inflammatory cytokine alterations in schizophrenia: a systematic quantitative review. Biological Psychiatry 63: 801-808, 2008.

8. Potvin S., Kouassi E., Lipp O, Bouchard R.H., Roy, M.A., Demers M.F., Gendron A., Astarita G., Piomelli D., and Stip E. Endogenous cannabinoids in patients with schizophrenia and substance use disorder during quetiapine therapy Journal of Psychopharmacology 22: 262-269, 2008.

9. Landau AM, Kouassi E, Siegrist-Johnstone R, Desbarats J. Unexpected findings in a proteasome inhibition model of Parkinson's Disease. Movement Disorders 22: 403-407, 2007.

10. Landau AM, Luk KC, Jones ML, Siegrist-Johnstone R, Young YK, Kouassi E, Rymar VV, Dagher A, Sadikot AF, Desbarats J. Defective Fas expression exacerbates neurotoxicity in a model of Parkinson's disease. The Journal of Experimental Medicine 202: 575-581, 2005.

11. Gendron A, Kouassi E, Nuara S, Cossette C, D'angelo G, Geadah D, du Souich P, Teitelbaum J. Transient middle cerebral artery occlusion influence on systemic oxygen homeostasis and erythropoiesis in Wistar rats. Stroke 35: 1979-1984, 2004.

12. Colombo M, Hamelin C, Kouassi E, Fournier M, Bernier J. Differential effects of mercury, lead, and cadmium on IL-2 production by Jurkat T cells. Clinical Immunology 111: 311-322, 2004.

13. Abdouh M, Albert PR, Drobetsky E, Filep JG, Kouassi E. 5-HT1A-mediated promotion of mitogen-activated T and B cell survival and proliferation is associated with increased translocation of NF-kappaB to nucleus. Brain, Behavior, and Immunity, 18 : 24-34, 2004.

14. Moisan E, Kouassi E, Girard D. Mechanisms involved in methylmercuric chloride (MeHgCl)-induced suppression of human neutrophil apoptosis. Human & Experimental Toxicology, 22: 629-637, 2003.

15. Gendron A, Teitelbaum J, Cossette C, Nuara S, Dumont M, du Souich P, Geadah D, Kouassi E. Temporal effects of left versus right middle cerebral artery occlusion on spleen lymphocyte subsets and mitogenic responses in Wistar rats. Brain Research 955: 85-97, 2002.

16. Moisan E, Arbour S, Nguyen N, Hébert MJ, Girard D, Bernier J., Fournier M, Kouassi E. Prolongation of human neutrophil survival by low-level mercury via inhibition of spontaneous apoptosis. Journal of Toxicology and Environmental Health, Part A, 65: 183-203, 2002.

17. Abdouh M, Storring JM, Riad M, Paquette Y, Albert PR, Drobetsky E, Kouassi E. Transcriptional mechanisms for induction of 5-HT1A receptor mRNA and protein in activated B and T lymphocytes. Journal of Biological Chemistry 276: 4382-4388, 2001.

18. Goulet AC, Goldmacher VS, Lambert JM, Roy DC, Baron C, Kouassi E. Conjugation of blocked ricin to an anti-CD19 monoclonal antibody increases antibody-induced cell calcium mobilization and CD19 internalization. Blood 90: 2364-2375, 1997.

19. Iken K, ChhengS, Fargin A, Goulet AC, Kouassi E. Serotonin up-regulates mitogen-stimulated B lymphocyte proliferation through 5-HT1A receptors. Cellular Immunology 163: 1-9, 1995.

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