Prof. Nicolas G. Bazan

Louisiana State University Health Sciences Center, USA

Email: nbazan@lsuhsc.edu

Qualifications

1970  Ph.D., Medical School, U. Tucuman

1965  M.Sc., Medical School, U. Tucuman

1958  B.Sc., Colegio Belgrano

Publications(Selected)

1. Stark, D.T., Bazan, N.G. Synaptic and extrasynaptic NMDA receptors differentially modulate neuronal COX-2 function, lipid peroxidation, and neuroprotection. J Neurosci. 2011 Sep 28;31(39):13710-21
2. Zhou, Y., Sheets, K.G., Knott, E.J., Regan, C.E. Jr., Tuo, J., Chan, C.C., Gordon, W.C., Bazan, N.G. Cellular and 3D Optical Coherence Tomography Assessment During the Initiation and Progression of Retinal Degeneration in the Ccl2/Cx3cr1-deficient Mouse. Exp. Eye Res. 2011 Nov;93(5):636-48
3. Cortina, M.S., He, J., Li, N., Bazan, N.G., Bazan, H.E. Recovery of corneal sensitivity, CGRP positive nerves and increased wound healing are induced by PEDF plus DHA after experimental surgery. Arch. Ophthal. 2011 (in press)
4. Molina, M.F., Bazan, N.G. The bioactive mediator neuroprotectin D1 derived from docosahexaenoic acid is a homeostatic cell survival sentinel in the nervous system. ASBMB Today 2011 Sep;52(9):1601-8
5. Musto, A.E., Gjorstrup, P., Bazan, N.G. The omega-3 fatty acid-derived neuroprotectin D1 limits hippocampal hyperexcitability and seizure susceptibility in kindling epileptogenesis. Epilepsia. 2011 (in press)
6. Mattson, M.P., Bazan, N.G. Apoptosis and Necrosis. In Basic Neurochemistry: Molecular, Cellular and Medical Aspects, 8th edition, G.Siegel, R.W. Albers, S.T. Brady, D.L. Price (eds.), 2011 (in press)
7. Belayev, L., Lu, Y. M., Bazan, N.G. Brain Ischemia and Reperfusion: Cellular and Molecular Mechanisms in Stroke Injury. In Basic Neurochemistry: Molecular, Cellular and Medical Aspects, 8th edition, G.Siegel, R.W. Albers, S.T. Brady, D.L. Price (eds.), 2011 (in press)
8. Bazan, N.G., Halabi, A., Ertel, M., Petasis, N.A. Neuroinflammation. In Basic Neurochemistry: Molecular, Cellular and Medical Aspects, 8th edition, G.Siegel, R.W. Albers, S.T. Brady, D.L. Price (eds.), 2011 (in press)
9. Bazan, N.G., Stark, D.T., Petasis, N.A. Lipid Mediators: Eicosanoids, Docosanoids and Platelet-Activating Factor. In Basic Neurochemistry: Molecular, Cellular and Medical Aspects, 8th edition, G.Siegel, R.W. Albers, S.T. Brady, D.L. Price (eds.), 2011 (in press)
10. Bazan, N.G., Molina, M.F., Gordon, W.C. Docosahexaenoic Acid Signalolipidomics in Nutrition: Significance in Aging, Neuroinflammation, Macular Degeneration, Alzheimer's and other Neurodegenerative Diseases. Annual Review of Nutrition 2011 31:321-51.
11. Stark, D.T., Bazan, N.G. Protectin D1 induces neuronal survival and downregulation of amyloidogenic processing in Alzheimer's disease cellular models. Mol Neurobio, (2011) 2:131-8
12. Musto, A.E., Gjorstrup, P., Bazan, N.G. The omega-3 fatty acid-derived neuroprotectin D1 limits hippocampal hyperexcitability and seizure susceptibility in kindling epileptogenesis. Epilepsia (2011) in press
13. Musto, A.E., Quebedeaux, T.M., Bazan, N.G. Hippocampal interneuronal cell loss is attenuated by neuroprotectin D1 with concomitant re-establishment of theta/gamma oscillations in status epilepticus. Epilepsia (2011) in press
14. Halapin NA, Bazan NG. NPD1 Induction of Retinal Pigment Epithelial Cell Survival Involves PI3K/Akt Phosphorylation Signaling. Neurochem. Res. (2010) 35:1944-1947
15. Zhao Y, Calon F, Julien C, Winkler JW, Petasis NA, Lukiw WJ, Bazan NG: Docosahexaenoic acid-derived neuroprotectin D1 induces neuronal survival via secretase- and PPARγ-mediated mechanisms in Alzheimer’s disease models. PLoS ONE (2010) 6:e15816
16. Kenchegowda, S., Bazan, N.G., Bazan, H.E. EGF stimulates lipoxin A4 synthesis and modulates repair in corneal epithelial cells through ERK and p38 activation. Invest. Ophthal. Vis. Sci. (2010) in press
17. Belayev, L., Khoutorova, L., Atkins, K.D., Eady, T.N., Hong, S., Lu, Y., Obenaus, A., Bazan, NG: Docosahexaenoic acid therapy of experimental ischemic stroke. Transl. Stroke Res. (2010) 2:33-41
18. Knott, E.J., Sheets, K.G., Zhou, Y., Gordon, W.C., Bazan, NG: Spatial correlation of mouse photoreceptor-RPE thickness between SD-OCT and histology. Exp. Eye Res. (2011) 92:155-160
19. Cui, J.G., Bazan, NG: Agrin down- or up-regulation mediates neuropathic pain. J. Neurosci. (2010) 30:15286-15297