Dr. Simon Quan-Bin Han

Hong Kong Baptist University, Hong Kong (China)

Email: simonhan@hkbu.edu.hk

Qualifications

2003 Ph.D., Chinese Academy of Sciences, Natural Product Chemistry Kunming Institute of Botany

2000 M.Sc., Henan University of Traditional Chinese Medicine

1996 B.Sc., Henan University of Traditional Chinese Medicine

Publications (selected)

1. Lin Li, Grace G.L. Yue, Clara B.S. Lau, Handong Sun, Kwok-pui Fung, Ping-chung Leung, Quan-Bin Han* and Po Sing Leung*, Eriocalyxin B induces apoptosis and cell cycle arrest in pancreatic adenocarcinoma cells through caspase- and p53-dependent pathways, Toxicology & Applied Pharmacology, 2012, 262, 80-90.
2. Xian-Jun Yu, Quan-bing Han*, Zhe-Sheng Wen, Liang Ma, Jin Gao Guang-Biao Zhou*, Gambogenic acid induces G1 arrest via GSK3β-dependent Cyclin D1 degradation and triggers autophagy in lung cancer cells, Cancer Letters, 2012, 322, 185-194.
3. Ben Chung Lap Chan, Margaret Ip, Hua Yu, Chun-Wai Wong, Claude Jolivalt, Marc Litaudon, Clara Bik San Lau, Sau Lai Lui, Kwok Pui Fung, Ping Chung Leung, and Quan-Bin Han*, Discovery of kuraridin, a nontoxic anti-bacterial agent against methicillin-resistant Staphylococcus aureus (MRSA), from Sophora flavescens by bioassay guided fractionation using high-speed counter-current chromatography, Journal of Chromatography B, 2012, 880,157-62.
4. Xiao-Qiang Han, Hua Yu, Ben Chung Lap Chan, Cai-Xia Dong, Yin-Hua Yang, Ke-Wang Luo, Chun-Hay Ko, David Wing-Shing Cheung, Kin-Ming Lee, Grace Gar-Lee Yue, Dan Chen, Chun-Kwok Wong, Clara Bik-San Lau, Peng-Fei Tu*, Pang-Chui Shaw, Kwok-Pui Fung, Ping-Chung Leung, Quan-Bin Han*, Isolation, structure characterization and immunomodulating activity of a hyperbranched polysaccharide from the fruiting bodies of Ganoderma sinense， Journal of Agricultural & Food Chemistry, 2012, 60, 4276-4281.
5. Xiao-Qiang Han, Ben Chung Lap CHAN, Hua Yu, Yin-Hua Yang, Shui-Qing Hu, Chun-Hay Ko, Cai-Xia Dong, Chun-Kwok Wong, Pang-Chui Shaw, Kwok-Pui Fung, Ping-Chung Leung, Wen-Luan Hsiao, Peng-Fei Tu*, Quan-Bin Han*, Structural characterization and immuno-modulating activities of a polysaccharide from Ganoderma sinense, Internat. J. Biol. Macromol., 2012, 51, 597-603.
6. Jun-Yi Yin, Ben Chung-Lap Chan, Hua Yu, Iris Yuen-Kam Lau, Xiao-Qiang Han, Sau-Wan Cheng, Chun-Kwok Wong, Clara Bik-San Lau , Ming-Yong Xie, Kwok-Pui Fung, Ping-Chung Leung, Quan-Bin Han*, Separation, structure characterization, conformation and immunomodulating effect of a hyperbranched heteroglycan from Radix Astragali, Carbohydrate Polymer, 2012, 87, 667-75.
7. Quan-Bin Han, Hong-Xi Xu, Caged Garcinia Xanthones, development since 1937, Current Medicinal Chemistry, 2009, 16, 3775-3796
8. Li-Mei Li, Zhi-Ying Weng, Sheng-Xiong Huang, Jian-Xin Pu, Sheng-Hong Li, Hao Huang, Bing-Bing Yang, Yu Han, Wei-Lie Xiao, Ma-Lin Li, Quan-Bin Han*, and Han-Dong Sun*, Cytotoxic ent-Kauranoids from the Medicinal Plant Isodon xerophilus. Journal of Natural Products, 2007, 70, 1295-1301.
9. Quan-Bin Han, Ting-Fai Tso, Susan Cheung, Joseph Tai, Chun-Feng Qiao, Jing-Zheng Song, Han-Dong Sun, Hong-Xi Xu, Maoecrystal Z, a Cytotoxic Diterpene from Isodon eriocalyx with an Unique Skeleton, Organic Letters, 2006, 8, 4727-4730.
10. Quan-Bin Han, Nian-Yun Yang, Hong-Lei Tian, Chun-Feng Qiao, Jing-Zheng Song, Donald C. Chang, Shi-Lin Chen, Kathy Q. Luo and Hong-Xi Xu, Xanthones with growth inhibition against HeLa cells from Garcinia xipshuanbannaensis, Phytochemistry, 2008, 69, 2187-2192
11. Quan Bin Han, Jing Zheng Song, Chun Feng Qiao, Lina Wong, Hong Xi Xu, Preparative separation of gambogic acid and its C-2 epimer using recycling high-speed counter-current chromatography, Journal of Chromatography A, 2006, 1127, 298-301.
12. Quan-Bin Han, Yue-Keung Yip, Nian-Yun Yang, Lina Wong, Chun-Feng Qiao, Jing-Zheng Song, Hillary Yiu, Hong-Xi Xu, Rapid analysis of pseudolaric acids in Cortex Pseudolaricis and related medicinal products by high performance liquid chromatography, Talanta, 2007, 73, 757-763.