Dr. Monalisa Mukherjea
Department of Physiology
University of Pennsylvania, USA

Research Associate Faculty

Email: mukherjm@mail.med.upenn.edu

Qualifications
2007 Ph.D., Tufts University, USA

1999 M.Sc., University Of Calcutta, India

1997 B.Sc., University Of Calcutta, India

Publications (Selected)

1. Ménétrey J., Isabet T., Ropars V., Mukherjea M., Pylypenko O., Liu X., Perez J., Vachette P., Sweeney H.L., Houdusse A. 2012. Processive steps in the reverse direction require uncoupling of the lead head lever arm of myosin VI. Molecular Cell, In Press.
2. Llinas P., Pylypenko O., Isabet T., Mukherjea M., Sweeney H.L., Houdusse A. 2012. How myosin motors power cellular functions: an exciting journey from structure to function. FEBS J. 279(4):551-62.
3. Mukherjea M., Llinas P., Kim H-J., Travaglia M., Safer D., Ménétrey J., Franzini-Armstrong C., Selvin P.R., Houdusse A., Sweeney H.L. Myosin VI dimerization triggers an unfolding of a 3-helix bundle in order to extend its reach. Molecular Cell, 35:305-15, 2009.
4. Ménétrey J., Llinas P., Mukherjea M., Sweeney H.L., Houdusse A. 2007. The Structural Basis for the Large Powerstroke of Myosin VI. Cell. 131, 300–308.
5. Chaudhuri T., Mukherjea M., Sachdev S., Randall J., Sarkar S. 2005.The role of the fetal and alpha/beta exons in the function of fast skeletal troponin T isoforms: Correlation with altered Ca2+ regulation associated with development. Journal of Molecular Biology. 352(1):58-71.
6. Gupta A., Neogi R., Mukherjea M., Mukhopadhyay A., Roychoudhury S., Senapati A., Gangopadhyay P.K., Ray K. 2003. DNA linkage based diagnosis of Wilson disease in asymptomatic siblings. Indian J Med Res. 118: 208-214.
7. Llinas P., Ménétrey J., Mukherjea M., Cicolari J., Sweeney H.L., Houdusse A. 2008.Structural view of the ATPase cycle of a myosin that moves backward.Acta Cystallographica. A64:C295.
8. Mukherjea M., Chaudhuri T., Randall J., Sarkar S. 2004.The Heptad Hydrophobic Repeat (HR) Domain of Troponin I: Role in Calcium Regulation of Vertebrate Striated Muscle Contraction.TheFASEB Journal 18: C192.
9. Chaudhuri T., Mukherjea M., Sachdev S., Sarkar S. 2004.Troponin T: Role of the alternatively spliced fetal and alpha/beta exons on the developmental regulation of calcium sensitivity in vertebrate fast skeletal muscle.TheFASEB Journal 18: C192.
10. Sarkar S., Chaudhuri T., Mukherjea M. 2006.C-terminus of Troponin I-Troponin T (TnI-TnT) Coiled-coil Structure: Effect on Troponin (Tn) Complex Function.The FASEB Journal.20:A1351.
11. Mukherjea M., Chaudhuri T., Randall J., Sarkar S. 2003.The heptad hydrophobic repeat (HR) domain of Troponin I: Role in calcium regulation of vertebrate striated muscle contraction. Journal of Muscle Research & Cell Motility. 24 (4-6): 329.
12. Chaudhuri T., Mukherjea M., Sachdev S., Sarkar S.2003.Troponin T: Role of the fetal and alpha/beta exons on the developmental regulation of calcium sensitivity in vertebrate fast skeletal muscle. Journal of Muscle Research & Cell Motility. 24 (4-6): 366.