Prof. Blanca Bazán Perkins

Departamento de Investigación en Hiperreactividad Bronquial

Instituto Nacional de Enfermedades Respiratorias, Mexico

Email: perkins@unam.mx

Qualifications

2001 Ph.D., Universidad Nacional Autónoma de México, Biomedicine

1994 M.Sc., Universidad Nacional Autónoma de México, Physiology

1991 B.Sc., Universidad Nacional Autónoma de México, Biology

Publications (Selected)

1. 2015 Alvarez-Santos MD, Ramos-Ramirez P, Gutierrez-Aguilar F, Sánchez-Hernandez S, Lascurain R, Olmos-Zuñiga R, Jasso-Victoria R, Bobadilla NA, Bazán-Perkins B. Antigen-induced airway hyperresponsiveness and obstruction is related to caveolin-1 expression in airway smooth muscle in a guinea pig asthma model. Clinical and Translational Allergy. 5:14.

2. 2015 Lucely Cetina, Tania Crombet, Roberto Jiménez-Lima, Sergio Zapata, Mayra Ramos, Sandra Avila, Jaime Coronel, Eduardo Charco, Rafael Bojalil, Horacio Astudillo, Blanca Bazán, Alfonso Dueñas-González. A pilot study of nimotuzumab plus single agent chemotherapy as second- or third-line treatment or more in patients with recurrent, persistent or metastatic cervical cancer. Cancer Biology & Therapy 16 (5): 684-9

3. 2014 Ramos-Ramírez P, Campos MG, Martínez-Cordero E, García-Zepeda E, Téllez-Jiménez O, Larios-Martínez K Bazán-Perkins B. Neutrophilia induced by histamine challenge in guinea pig: The role of IL‑5, IL‑10 and IL‑17A, but no CXCL8. Boletín Médico del Hospital Infantil de México, 71 (2): 83-87..

4. Ramos-Ramírez P, Campos MG, Martínez-Cordero E, Bazán-Perkins B, García-Zepeda E. Antigen-induced airway hyperresponsiveness In absence of broncho-obstruction in sensitized guinea pigs. Experimental Lung Research, 39, 136–145.

5. Oropeza M., Calzada C, Guerra-Araiza C., Bazán-Perkins B. Mendoza-Espinoza J. Campos MG, Tibolone induces serotonin, estrogen and progesterone receptor expression but not contractile response to serotonin in the rat uterus. Hormone and Metabolic Research 45 (7): 490-4.

6. 2012 Bazán-Perkins B. cGMP reduces the sarcoplasmic reticulum Ca2+ loading in airway smooth muscle cells: a putative mechanism in the regulation of Ca2+ by cGMP  Journal of Muscle Research and Cell Motility, 32 (6): 375-82.

7. 2011 Campos M.G., Bazán-Perkins B. Asthma: relationships and mechanisms. Boletín Médico del Hospital Infantil de México 68 (3): 169-170.

8. 2010 Vargas MH, Sommer B, Bazán-Perkins B, Montaño LM. Airway responsiveness measured by barometric plethysmography in guinea pigs. Veterinary Research Communications, 34 (7): 589-596.

9. 2010 Sánchez-Pozos K., Lee-Montiel F., Pérez R., Uribe N.,  Gamba G., Bazan-Perkins B., Bobadilla N.A. Polymerized type I collagen reduces chronic cyclosporine (CsA) nephrotoxicity. Nephrology Dialysis Transplantation 25 (7): 2150-2158.

10. 2010 Moreno-Álvarez P., Sánchez-Guerrero E., Martínez-Cordero E., Hernández-Pando R., Campos M.G., Cetina L., Bazan-Perkins B. Aerosolized polymerized type I collagen reduces airway inflammation and remodelling in a guinea pig model of allergic asthma. Lung 188 (2): 97-105.

11. 2009 Bazán-Perkins B., Sánchez-Guerrero E., Campos M.G. Capacitative Ca2+ entry during Ca2+ undershoot in bovine airway smooth muscle. Cellular Physiology and Biochemistry, 24: 161-166.

12. 2009 Bazán-Perkins B., Sánchez-Guerrero E., Vargas M., Martinez E., Ramos-Ramírez P., Alvarez-Santos M., Hiriart G., Gaxiola M., Hernández-Pando R. β1-Integrins shedding in a guinea pig model of chronic asthma with remodelled airways. Clinical and Experimental Allergy, 39: 740-751.

13. 2009 Cetina L, Garcia-Arias A, Candelaria M, Cantu D, Rivera L, Coronel J, Bazan-Perkins B, Flores V, Gonzalez A, Duenas-Gonzalez A. Brachytherapy versus radical hysterectomy after external beam chemoradiation: a non-randomized matched comparison in IB2-IIB cervical cancer patients. World Journal of Surgical Oncology 7 (1): 19.

14. 2005 Montaño L.M., Bazán-Perkins B. Resting calcium influx in airway smooth muscle. Canadian Journal of Physiology and Pharmacology, 83 (8-9): 717-723.

15. 2005 Carbajal V., Vargas M., Flores-Soto E., Martínez-Cordero E., Bazán-Perkins B. y Montaño L.M. LTD4 induces hyperresponsiveness to histamine but not to carbachol in bovine airway smooth muscle: Role of SR-ATPase Ca2+ pump and tyrosine kinase pathway. American Journal of Physiology: Lung Cellular and Molecular Physiology 288: L84-L92.

16. 2004 Bazán-Perkins B., Vargas M.H., Sánchez-Guerrero E., Chávez J. y L.M. Montaño. Spontaneous changes in guinea pig respiratory pattern during barometric plethysmography: Role of catecholamines and nitric oxide. Experimental Physiology, 85: 623-628.

17. 2003 Bazán-Perkins B., Flores E., Barajas-López C. y L.M. Montaño. Role of sarcoplasmic reticulum Ca2+ content in Ca2+ entry of bovine airway smooth muscle cells. Naunyn-Schmiedeberg´s Archives of Pharmacology 368: 277–283.

18. 2000 Bazán-Perkins B., Sánchez-Guerrero E., Carbajal V., Barajas-López C. y L.M. Montaño. Sarcoplasmic reticulum Ca2+ depletion by caffeine and changes of [Ca2+]i during refilling in bovine airway smooth muscle cells. Archives of Medical Research 31: 558-563.

19. 1998 Bazán-Perkins B., Carbajal V., Sommer B., Macías-Silva M., Gonzáles-Martínez M., Valenzuela F., Daniel E.E. y L.M. Montaño. Involvement of different Ca2+ pools during the canine bronchial sustained contraction in Ca2+ free medium: Lack of effect of PKC inhibition. Naunyn-Schmiedeberg´s Archives of Pharmacology 358: 567-573.

20. 1997 Sommer B., Vargas M., Segura P., Bazán-Perkins B., Carbajal V., Chávez J., Gustin P. y L.M. Montaño. Effect of different ozone concentrations on the neurogenic contraction and relaxation of guinea pig airways. Fundamental and Clinical Pharmacology 11: 501-511.