Prof. Xiao-Feng Li

Chairman of Department of Nuclear Medicine

Shenzhen People’s Hospital, Shenzhen, China

Professor

Email: linucmed@gmail.com

Qualifications

2003 Ph.D., Kanazawa University Graduate School of Medical Sciences
1993 M.D., Norman Bethune University of Medical Sciences

Publications (selected)

1. Li XF, et al. Benefits of combined radioimmunotherapy and anti-angiogenic therapy in a liver metastasis model of human colon cancer cells. European Journal of Nuclear Medicine Molecular Imaging. 2002; 29: 1669-74.
2. Li XF, Zanzonico PB, Ling CC and O’Donoghue JA. Visualization of experimental lung and bone metastases in live nude mice by X-ray micro-computed tomography. Technology in Cancer Research &Treatment.2006; 5: 147-55. PMID:16551134.
3. Li XF, O'Donoghue JA. Visualization of hypoxia in microscopic tumors by immunofluorescent microscopy. Cancer Research. 2007; 67(16):7646-53 (cover image). PMID:17699769.
4. Li XF, O’Donoghue JA. Hypoxia in microscopic tumors. Cancer Letters. 2008; 264: 172-180. PMID:18384940, PMCID:PMC2460565.
5. Li XF, O’Donoghue JA. High 18F-FDG uptake in microscopic peritoneal tumors requires physiological hypoxia. Journal of Nuclear Medicine. 2010;51:632-8. PMID: 20351353,  PMCID:PMC2917184.
6. Li XF, O’Donoghue JA. Detection of hypoxia in microscopic tumors using 131I-labeled iodo-azomycin galactopyranoside digital autoradiography. European Journal of Nuclear Medicine Molecular Imaging. 2010; 37:339–348. PMID:19921184  PMCID: PMC2891169.
7. Huang T, Li XF. Tumor Microenvironment–Dependent 18F-FDG,18F-Fluorothymidine, and 18F-Misonidazole Uptake: A Pilot Study in Mouse Models of Human Non–Small Cell Lung Cancer. Journal of Nuclear Medicine.2012; 53:1262–1268. PMID: 22717978.
8. Huang T, Li XF. 18F-misonidazole PET imaging hypoxia in micrometastases and macroscopic xenografts of human non-small cell lung cancer:  Correlating with autoradiographic and histological findings. Am J Nucl Med Mol Imaging. 2013;3(2):142-153. PMID:23526377.
9. Li XF, et al. Combination of 18F-fluorodeoxyglucose and 18F-fluorothymidine PET achieves more complete identification of viable cancer cells in lung cancer of the mouse and the patient than individual radiopharmaceutical: A proof-of-concept study. Translational Oncology. 2013; 6:775–783.  PMCID: PMC3890713.
10. Li XF, et al. 18F-fluorodeoxyglucose uptake and tumor hypoxia: Revisit 18F-fluorodeoxyglucose in oncology application. Translational Oncology. 2014;7:240-247. PMID:24699008.
11. Zhang G, Li XF. The reverse Warburg effect and18F-FDG uptake in non-small cell lung cancer A549 in mice: A pilot study Journal of Nuclear Medicine 2015; 56:607–612.
12. Li J, Li XF. Is carbonic anhydrase IX a validated target for molecular imaging of cancer and hypoxia? Future Oncology.  2015;11(10):1531-41.