Prof. Mirko Diksic

McGill University, Canada




1970  Ph.D., University of Zagreb, Croatia

1968  M.Sc., University of Zagreb, Croatia


  1. ELMENHORST1 D, MINUZZI L, ALIAGA A, ROWLEY J, MASSARWEH G, DIKSIC M, BAUER A, ROSA-NETO P. In vivo and in vitro validation of reference tissue models for the mGluR(5) ligand [(11)C]ABP688. J Cereb Blood Flow Metab. 30(8) (2010) 1538-49.
  2. BOOIJ L, TREMBLAY RE, LEYTON M, SÉGUINC JR, VITARO F, GRAVEL P, PERREAU-LINCK E, LÉVESQUE ML; DURAND F, DIKSIC M, TURECKI G, BENKELFATC: Brain Serotonin Synthesis in Adult Males Characterized by Physical Aggression During Childhood: a 21-year Longitudinal Study. Plos One 5(6) (2010) 1-9.
  3. FREY BN, SKELIN I, SAKAI Y, NISHIKAWA M, DIKSIC M: Gender differences in α-[11C]MTrp brain trapping, an index of serotonin synthesis, in medication-free individuals with major depressive disorder: a positron emission tomography study. Psychiatry Research, Neuroimaging 183 (2010) 157–166.
  4. SATO H, SKELIN I, DIKSIC M. Chronic buspirone treatment decreases 5-HT1B receptordensities and the serotonin transporter but increases the density of 5-HT2A receptors in thebulbectomized rat model of depression: an autoradiographic study. Brain Res, 1345 (2010) 28-44.
  5. SKELIN I, KOVAČEVIĆ T, SATO H, DIKSIC M. Upregulated arachidonic acid signalling in the olfactory bulbectomized rat model of depression. Neurochem Int, 58 (2011) 483–488.
  6. BERNEY A, LEYTON M, GRAVEL P, SIBON I, SOOKMAN D, ROSA NETO P,DIKSIC M, NAKAI A, PINARD G, TODOROV C, OKAZAWA H, BLIER P, NORDAHL TE, BENKELFAT C. Brain Regional α-[11C]Methyl-L-Tryptophan Trapping in Medication-Free Patients With Obsessive-Compulsive Disorder. Arch Gen Psychiatry, 68(7) (2011) 732-41.
  7. BOOIJ L, TURECKI G, LEYTON M, GRAVEL P, LOPEZ DE LARA C, DIKSIC M, BENKELFAT C. Tryptophan Hydroxylase 2 Gene Polymorphisms Predict Brain Serotonin Synthesis in the Orbitofrontal Cortex in Humans. Molecular Psychiatry, July 12, 2011; doi:10.1038/mp.2011.79.
  8. SATO H, SKELIN I, DIKSIC M. Acute desipramine treatment reduces regional serotonin synthesis rates, while chronic treatment elevates rates, in a rat model of depression: an autoradiographic study. Neurochem Int., 58 (2011) 759-766.
  9. PIVAC N, DIKSIC M. The lumped constant of α-methyl-L-tryptophan is not influenced by drugs acting through serotonergic system. Neurochem Int., 58 (826-832).

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