Dr. Mateus Webba da Silva

School of Biomedical Sciences

University of Ulster, Coleraine, UK

Email: mm.webba-da-silva@ulster.ac.uk


2008 Visiting Fellowship, University of Kyoto, Japan

1996 Ph.D., University of Exeter, Chemistry

1992 M.Sc., Universidade Agostinho Neto, Chemistry

Publications (Selected)

  1. M. Trajkovski, M. Webba da Silva, Janez Plavec*. Unique structural features of interconverting monomeric and dimeric G-quadruplexes adopted by a sequence from intron of N-myc gene, J. Am. Chem. Soc., 134 (2012) 4132 - 4141.
  2. I. Karsisiotis, N. M. Hessari, Ettore Novellino, G. P. Spada,* A. Randazzo,* M. Webba da Silva*. Topological Characterization of G-Quadruplexes by UV Absorption and Circular Dichroism, Angew. Chem. Int. Ed. Engl. 50 (2011) 10645-10648. (Hot Paper)
  3. P. Groves,* M Webba da Silva*. Rapid Stoichiometric Analysis of G-Quadruplexes in Solution. Chem. Eur. J., 16 (2010) 6451-6453.
  4. M. Webba da Silva,* M. Trajkovski, Y. Sannohe, N. M. Hessari, H. Sugiyama, J. Plavec*. Design of a G-Quadruplex Topology through Glycosidic Bond Angles, Angew. Chem. Int. Ed. Engl. 48 (2009) 9167-9170.
  5. M. Webba da Silva. Geometric Formalism of DNA Quadruplex Folding, Chem. Eur. J., 13 (2007) 9738-9745.
  6. J.-L. Mergny*, A. De Cian, S. Amrane, M. Webba da Silva*. Kinetics of Double-Chain Reversals Bridging Contiguous Quartets in Tetramolecular Quadruplexes, Nucl. Acids Res., 34 (2006) 2386-2397.
  7. M. Webba da Silva. Experimental Demonstration of T:(G:G:G):T Hexad and T:A:A:T Tetrad Alignments within a DNA Quadruplex Stem, Biochemistry, 44 (2005) 3754-3764.
  8. M. Webba da Silva, A.M. Noronha, D.M. Noll, P.S. Miller, O.M. Colvin, M. P. Gamcsik. Solution Structure of a DNA Duplex Containing Mispair-Aligned N4C-Ethyl-N4C Interstrand Cross-Linked Cytosines, Biochemistry, 41 (2002) 15181-15188.
  9. M. Webba da Silva, S. Sham, C.M. Gorst, L. Calzolai, P.S. Brereton, M.W.W. Adams, G.N. La Mar. Solution NMR Characterization of the Thermodynamics of the Disulfide Bond Orientational Isomerism and Its Effect on Cluster Properties for the Hyperthermostable Three-Iron Cluster Ferredoxin from the Archaeon Pyrococcus Furiosus, Biochemistry, 40 (2001) 12575-12583.