Prof. Alireza G. Senejani
Yale University School of Medicine, USA
Associate Research Scientist
Email: Alireza.senejani@yale.edu
Qualifications
2013 Post doctorate, Yale University, USA
2007 Ph.D., Genetics, University of Connecticut, USA
2000 M.Sc., Biotechnology, Mannheim University of Applied Science, Germany
1998 B.Sc., Biochemistry, Aligarh University, India
Publications (Selected)
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Lokanga R.,
Senejani A.G., Sweasy J.B., Usdin K. “Heterozygosity for a hypomorphic Polβ
mutation reduces the expansion frequency in a mouse model of the repeat
expansion disease Fragile X syndrome” 2015 PLoS Genetics. 2015 Apr 17; 11(4).
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Park H.J., Kim
D.H., Choi J.Y., Kim W.J., Kim J.Y., Senejani A.G., Hwang S.S., Kim, L.K.,
Tobiasova Z., Lee G.R., Craft J., Choi J., Bothwell A.L., Choi J. M. “PPARγ
negatively regulates T cell activation to prevent follicular helper T cells and
germinal center formation” PLoS One 2014 June 12; 9(6).
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Senejani A.G.,
Liu Y., Kidane D., Maher S.E., Zeiss C.J., Park H., Kashgarian M., McNiff J.M.,
Zelterman D., Bothwell A., Sweasy J.B. “Mutation of A DNA Repair Enzyme Causes
Lupus in Mice” Cell reports (CELL PRESS) 2014 Jan 16; 6(1): 1-8. doi:
10.1016/j.celrep.2013.12.017. Epub 2014 Jan 2.
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Ray S.,
Menezes M.R., Senejani A., Sweasy J.B. “Cellular Roles of DNA Polymerase Beta”
Yale J Biol Med 2013 Dec 13; 86(4): 463-469.
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Sjolund A,
Senejani AG, Sweasy JB “MBD4 and TDG: Multifaceted DNA Glycosylases With Ever
Expanding Biological Roles” (submitted).
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Senejani AG,
Dalal S, Liu Y, Nottoli, T, McGrath J, Clairmont CS, Sweasy JB “Y265C DNA
Polymerase Beta Knockin Mice Survive Past Birth and Accumulate Base Excision
Repair Intermediate Substrates” Proc Natl Acad Sci U S A. 2012 Apr 24; 109(17): 6632-7.
Epub 2012 Apr 9.
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Senejani, A.G.
and Sweasy, J.B.; Eukaryotic gene invasion by a bacterial mobile Insertion
sequence element IS2 during cloning into a plasmid vector; Genome Intergrity.
2010 May 26; 1(1): 2.
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Swithers K.S.,
Senejani A.G, Fournier G.P., Gogarten J.P.; Conservation of intron and intein
insertion sites: implications for life histories of parasitic genetic elements.
BMC Evol Biol. 2009; 9: 303“ BMC Highly accessed article”.
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Senejani, A.G.
and Gogarten, J.P.; Structural stability and endonuclease activity of PI-SceI
GFP-fusion protein; Int J Biol Sci 2007; 3: 205-211.
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Gogarten,
J.P., Senejani, A.G., Zhaxybayeva, O., Olendzenski, L. and Hilario, E.;
Inteins: Structure, Function, and Evolution Annul. Review of Microbiology.
2002, 56: 263-287.
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Senejani,
A.G., Hilario, E., and Gogarten, J.P.; The intein of the Thermoplasma A-ATPase
A subunit: Structure, evolution and expression in E. coli. BMC Biochemistry
2001 2(1): 13,1-10.
Last Updated: July, 2015