Biography

Prof. Seung Joon Baek

University of Tennessee, USA


Email: sbaek2@utk.edu


Qualifications


1998 Ph.D., University of Maryland School of Medicine, Human Genetics

1991 M.Sc., Seoul National University, Agricultural Chemistry

1989 B.Sc., Seoul National University, Agricultural Chemistry


Publications (selected)

  1. Iguchi G, Chrysovergis K, Lee SH, Baek SJ, Langenbach R, and Eling TE. (2009) A reciprocal Relationship Exists Between Nonsteroidal Anti-Inflammatory Drug-Activated Gene-1 (NAG-1) and Cyclooxygenase-2. Can Lett. Sep 18;282(2):152-8. PMID: 19375854
  2. Peretich A, Cekanova M, Hurst S, Baek SJ, and Dhar M. (2009) PPAR agonists down-regulate the expression of Atp10c mRNA during adipogenesis. Open Obesity J. Nov 1:41-48.
  3. Kambe S, Yoshioka H, Kamitani H, Watanabe T, Baek SJ, and Eling TE. (2009) The Cyclooxygenase Inhibitor Sulindac Sulfide Inhibits EP4 Expression and Suppresses the Growth of Glioblastoma Cells. Cancer Prev Res (Phila Pa). Dec 2:1088-1099. PMCID: PMC2789193
  4. Rojsanga P, Sukthankar M, Krisanapun C, Gritsanapan W, Lawson DB, and Baek SJ. (2010) In vitro Anti-proliferative Activity of Alcoholic Stem Extract of Coscinium fenestratum in human colorectal cancer cells. Exp Ther Med. Jan 1(1): 181-186. PMCID:PMC3490397
  5. Choi CK, Sukhthankar M, Kim C, Lee SH, English A, Kihm KD,  and Baek SJ (2010) Cell adhesion property affected by cyclooxygenase and lipoxygenase: Opto-electric approach. Biochem Biophys Res Commun Jan 391 (3):1385-1389. PMCID: PMC2814420
  6. Sukthankar M, Choi CK, English AE, Kim JS and Baek SJ (2010) A potential proliferative gene, NUDT6, is down-regulated by green tea catechins at the posttranscriptional level. J Nutr Biochem. Feb 21(2): 98-106. PMCID: PMC2840651
  7. Lee SH, Krisanapun C and Baek SJ (2010) NSAID-activated gene-1 as a molecular target for capsaicin-induced apoptosis through a novel molecular mechanism involving GSK3beta, C/EBPbeta and ATF3. Carcinogenesis. Apr 31(4):719-728. PMCID: PMC2847092
  8. Cekanova M, Lee SH, McEntee M, and Baek SJ (2010) MCC-555-induced NAG-1 expression is mediated in part by KLF4. Eur J Pharmacol. July 637(1-3):30-37.
  9. Kim CH, Kwon S, Bahn JH, Lee K, Jun S, Rack PD, and Baek SJ (2010) Effects of atmospheric non-thermal plasma on invasion of colorectal cancer cells. App. Physics Letter. June 96(24):243701. PMCID: PMC2902543
  10. Sukhthankar M, Alberti S, and Baek SJ (2010) (-)-Epigallocatechin-3-Gallate (EGCG) Post-transcriptionally and Post-translationally Suppresses the Cell Proliferative Protein Trop-2 in Human Colorectal Cancer Cells. Anticancer Res. July 30(7):2497-503. PMID: 20682974
  11. Close D, Patterson S, Ripp S, Baek SJ, Sanseverino J, Sayler G (2010) Autonomous Bioluminescent Expression of the Bacterial Luciferase Gene Cassette (lux) in a Mammalian Cell Line. PLoS ONE. Aug 5(8): e12441.
  12. Kim HJ, Ryu JH, Kim CH, Lim JW, Moon UY, Lee GH, Lee JG, Baek SJ, Yoon JH (2010) ECG Suppresses Oxidative Stress-Induced MUC5AC Overexpression by Interaction with EGFR. Am J Respir Cell Mol Biol. Sep 43(3):349-357.
  13. Lee SH, Bahn JH, Whitlock NC, and Baek SJ (2010) Activating transcription factor 2 (ATF2) controls tolfenamic acid-induced ATF3 expression via MAP kinase pathways. Oncogene. Sep 29(37): 5182-5192. PMCID: PMC2940954
  14. Kim CH, Bahn JH, Lee SH, Kim GY, Jun SI, Lee KH and Baek SJ (2010)
  15. Induction of cell growth arrest by atmospheric nonthermal plasma in colorectal cancer cells. J Biotechnol. Dec 150(4): 530-538. PMID: 20959125.
  16. Zhong Y, Krisanapun C, Lee SH, Nualsanit T, Sams C, Peungvicha P, and Baek SJ (2010) Molecular targets of apigenin in colorectal cancer cells: Involvement of p21, NAG-1 and p53. Eur J Cancer. Dec 46(18): 3365-3374. PMCID: PMC2988105
  17. Whitlock N, Bahn JH, Lee SH, Eling TE, and Baek SJ (2011) Resveratrol-induced apoptosis is mediated by Early Growth Response-1, Krüppel-Like Factor 4, and Activating Transcription Factor 3. Cancer Prev Res. Jan 4 (1):116-127. PMCID: PMC3064282
  18. Krisanapun C, Lee SH, Peungvicha P, Temsiririrkkul R, and Baek SJ (2011) Antidiabetic properties involved ininsulinsensitivity of Abutilon indicum Sweet are mediated by enhancement of adipocyte differentiation and activation of GLUT1 promoter. Evid Based Complement Alternat Med. article ID 2011:167684.
  19. Close D, Hahn RE, Patterson S, Baek SJ, Ripp SA, and Sayler G (2011) Comparison Of Human Optimized Bacterial Luciferase, Firefly Luciferase, And Green Florescent Protein For Continuous Imaging Of Cell Cultures And mouse Models.J Biomed Opt. Apr 16(4):047003. PMID: 21529093
  20. Flatland B, Fry MM, Baek SJ, Bahn JH, LeBlanc CJ, Dunlap JR, Carroll RC, Kosiba DJ, Millsaps DJ, and Schleis SE. (2011) May-Hegglin Anomaly in a Dog. Vet. Clin. Pathol. June 40(2):207-214. PMID:21554370.
  21. Margraves CH, Kihm KD, Yoon SY, Choi CK, Lee SH, Liggett JL, Baek SJ. (2011) Simultaneous Measurements of Cytoplasmic Viscosity and Intracellular Vesicle Sizes for Live Human Brain Cancer Cells. Biotechnol Bioeng. Oct 108(10):2504-2508.
  22. Huang EC, Chen G, Baek SJ, McEntee MF, Collier JJ, Minkin S, Biggerstaff J and Whelan J. (2011) Zyflamend® Reduces the Expression of Androgen Receptor in a Model of Castrate-Resistant Prostate Cancer. Nutr. Cancer. Nov 63(8):1287-1296.
  23. Nualsanit T, Rojanapanthu P, Gritsanapan, W, Kwankitpraniti T, Min KW, and Baek SJ. (2011) Damnacanthal-induced Anti-inflammation is Associated with Inhibition of NF-κB Activity. Inflamm Allergy Drug Targets. Dec 10(6):455-463.
  24. Kang SU, Shin YS, Hwang HS, Baek SJ, Lee SH, and Kim CH. (2012) Tolfenamic Acid Induces Apoptosis and Growth Inhibition in Head and Neck Cancer: Involvement of NAG-1 Expression. Apr 7(4): e34988. PLoS ONE.
  25. Lee SH, Richardson RL, Dashwood RH, and Baek SJ (2012) Capsaicin represses transcriptional activity of β-catenin in human colorectal cancer cells. J Nutr Biochem. June 23(6): 646-655. PMCID:PMC3197951.
  26. Nualsanit T, Rojanapanthu P, Gritsanapan W, Lee SH, Lawson DB and Baek SJ (2012) Damnacanthal, a Noni component, exhibits anti-tumorigenic activity in human colorectal cancer cells. J Nutr Biochem. Aug 23(8): 915-923.
  27. Min KW, Zhang X, Imchen T, and Baek SJ (2012) MCC-555 Enhances Anti-tumorigenic Activity in Pancreatic Cancer Cells via Multiple Targets. Toxicol Appl Pharmacol. Sep 263(2):225-232. PMCID:PMC3443873.
  28. Zhang X, Min KW, Wimalasena J, and Baek SJ (2012) Cyclin D1 degradation and p21 induction contribute to growth inhibition of colorectal cancer cells induced by Epigallocatechin-3-gallate. J Can Res Clin Oncol. Dec 138(12):2051-60.
  29. Lee SH, Min KW, Zhang X, and Baek SJ. (2013) 3,3'-diindolylmethane induces activating transcription factor 3 (ATF3) via ATF4 in human colorectal cancer cells. J Nutr Biochem. Apr 24(4): 664-671. PMCID:PMC3481000
  30. Kim JM, Kosak JP, Lim JK, Kissling G, Germolec DR, Zeldin DC, Bradbury JA, Baek SJ and Eling TE (2013) NAG-1/GDF15 transgenic mouse has less white adipose tissue and a reduced inflammatory response. Mediators Inflamm. May 2013 Article ID 641851. PMCID: PMC3662179.
  31. Pandith H, Zhang X, Thongpraditchote S, Wongkrajang Y, Gritsanapan W and Baek SJ. (2013) Effect of Siam Weed Extract and its Bioactive Component Scutellarein Tetramethyl Ether on Anti-inflammatory Activity. J Enthopharm. May 147(2): 434-441. PMID: 23535395
  32. Kang SU, Lee B-S, Lee S-H, Baek SJ, Shin YS, and Kim C-H (2013) Expression of NSAID-activated gene-1 by EGCG in head and neck cancer: involvement of ATM-dependent p53 expression. J Nutr Biochem. June 24(6): 986-999.
  33. Pandith H, Zhang X, Liggett J, Min KW, Gritsanapan W and Baek SJ. (2013) Effect of Chromolaena Odorata Extract on Wound Healing Activity. ISRN Dermatol. Aug 2013: 168269. PMCID: PMC3747403.
  34. Imchen T, Manasse J, Min KW, Baek SJ. (2013) Characterization of PPAR dual ligand MCC-555 in AOM-induced colorectal tumorigenesis. Exp Toxicol Pathol. Sep 65(6): 919-924. PMCID: PMC3644347.
  35. Jeong JB, Choi J, Baek SJ, and Lee SH. (2013) Reactive oxygen species mediate tolfenamic acid-induced apoptosis in human colorectal cancer cells. Arch Biochem Biophys. Sep 537(2): 168-175. PMID: 23896517.
  36. Jeong JB, Yang X, Clark R, Choi J, Baek SJ, and Lee SH. (2013) Tolfenamic acid-induced apoptosis is mediated by NF-κB activation in human colorectal cancer cells. Carcinogenesis. Oct 34(10): 2350-2360. PMID: 23784084.
  37. Zhang X, Lee SH, Min KW, McEntee MF, Jeong JB, Li Q, and Baek SJ. (2013) Nonsteroidal anti-inflammatory drug tolfenamic acid inhibits colorectal tumorigenesis via endoplasmic reticulum stress. Cancer Prev Res. Dec 6(12):1-11.
  38. Liggett JL, Choi CK, Donnell RL, Kihm KD, Kim JS, Min KY, Noegel AA, and Baek SJ (2014) Nonsteroidal anti-inflammatory drugs suppress structural protein Nesprin-2 expression in colorectal cancer cells. Biochim Biophys Acta. Jan 1840(1): 322-331. PMID: 24080406.

Profile Details

http://www.vet.utk.edu/carcinogenesis_lab/index.php


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