Prof. James Chung-man Ho

University of Hong Kong, China

Email: jhocm@hku.hk

Qualifications

2007 M.D., University of Hong Kong, Medical Faculty

1993 M.B., B.S., University of Hong Kong, Medical Faculty

Publications (selected)

1. Ho JC, Wong MP, Lam WK. Invited review: Lymphoepithelioma-like carcinoma of the lung. Respirology 2006;11:539-545.
2. Ho JC, Chan-Yeung M, Ho SP, Mak JC, Ip MS, Ooi GC, Wong MP, Tsang KW, Lam WK. Disturbance of systemic antioxidant profile in non-small cell lung carcinoma. Eur Respir J 2007;29:273-278.
3. Wong MK, Wong MP, Lam DC, Sihoe A, Cheng LC, Lam B, Ip MS, Nakajima T, Yasufuku K, Lam WK, Ho JC. Endobronchial ultrasound for diagnosis of synchronous primary lung cancers. Lung Cancer 2009;63:154-157.
4. Ho JC, Lam DC, Wong MK, Lam B, Ip MS, Lam WK. Capecitabine as salvage treatment for lymphoepithelioma-like carcinoma of lung. Journal of Thoracic Oncology 2009;4(9):1174-1177.
5. Wong MK, Lo AI, Lam B, Lam WK, Ip MS, Ho JC. Erlotinib as salvage treatment after failure to first-line gefitinib in non-small cell lung cancer. Cancer Chemotherapy and Pharmacology 2010;65(6):1023-1028.
6. Chiu PC, Liao S, Lam KK, Tang F, Ho JC, Ho PC, O WS, Yeung WS. Adrenomedullin regulates sperm motility and oviductal ciliary beat via cAMP/protein kinase A and nitric oxide. Endocrinology 2010;151:3336-3347.
7. Li HW, Liao SB, Chiu PC, Tam WW, Ho JC, Ng EH, Yeung WS, Tang F, O WS. Expression of adrenomedullin in human oviduct, its regulation by the hormonal cycle and contact with spermatozoa, and its effect on ciliary beat frequency of the oviductal epithelium. Journal of Clinical Endocrinology and Metabolism 2010;95:E18-25.
8. Liao SB, Ho JC, Tang F, O WS. Adrenomedullin increased ciliary beat frequency and decreased muscular contraction in the rat oviduct. Reproduction 2011;141(3):367-72.
9. Wong MK, Tam TC, Lam DC, Ip MS, Ho JC. EBUS-TBNA in patients presented with superior vena cava syndrome. Lung Cancer 2012;77(2):277-80.
10. Yam I, Lam DC, Chan K, Ho JC, Ip M, Lam WK, Chan TK, Chan V. EGFR array: uses in detection of plasma EGFR mutations in non-small cell lung cancer patients. Journal of Thoracic Oncology 2012 ;7:1131-1140.
11. Siu CW, Wong MP, Ho CM, Lam CL, Tse HF. Fatal lung toxicity related to dronedarone.  Archive of Internal Medicine 2012:172(6):516-517.
12. Liao SB, LI HWR, Ho JC, Yeung WSB, Ng EHY, Cheung ANY, Tang F, O WS. Possible role of adrenomedullin in the pathogenesis of tubal ectopic pregnancy. Journal of Clinical Endocrinology and Metabolism 2012;97(6):2105-2112.
13. Lee CK, Brown C, Gralla R, Hirsh V, Thongprasert S, Tsai CM, Tan EH, Ho JC, Chu DT, Zaatar A, Sanchez JO, Vu VV, Au JS, Inoue A, Lee SM, Gebski V, Yang JC. Impact of epidermal growth factor receptor inhibitor in non-small cell lung cancer on progression-free and overall survival: a meta-analysis. J Natl Cancer I 2013;105(9):595-605.
14. Thompson P, Salvi S, Lin J, Cho YJ, Eng P, Manap RA, Boonsawat W, Hsu JY, Faruqi RA, Moreno-Cantu JJ, Fish JE, Ho JC. Insights, attitudes, and perceptions about asthma and its treatment: Findings from a multinational survey of patients from 8 Asia-Pacific countries and Hong Kong. Respirology 2013;18(6):957-67.
15. Li YY, Lam SK, Mak JC, Zheng CY, Ho JC. Erlotinib-induced autophagy in epidermal growth factor receptor mutated non-small cell lung cancer. Lung Cancer 2013;81(3):354-61.
16. Wu YL, Lee JS, Thongprasert S, Yu CJ, Zhang L, Ladrera G, Srimuninnimit V, Sriuranpong V, Sandoval-Tan J, Zhu Y, Liao M, Zhou C, Pan H, Lee V, Chen YM, Sun Y, Margono B, Fuerte F, Chang GC, Seetalarom K, Wang J, Cheng A, Syahruddin E, Qian X, Ho JC, Kurnianda J, Liu HE, Jin K, Truman M, Bara I, Mok TS. Intercalated combination of chemotherapy and erlotinib for patients with advanced stage non-small cell lung cancer. Lancet Oncol 2013;14(8):777-86.
17. Zheng CY, Lam SK, Li YY, Fong BM, Mak JC, Ho JC. Combination of arsenic trioxide and chemotherapy in small cell lung cancer. Lung Cancer 2013;82(2):222-30.
18. Lam SK, Mak JC, Zheng CY, Li YY, Kwong YL, Ho JC. Downregulation of thymidylate synthase with arsenic trioxide lung adenocarcinoma. Int J Oncol 2014;44(6):2093-102.
19. Lam SK, Li YY, Zheng CY, Leung LL, Ho JC. E2F1 downregulation by arsenic trioxide in lung adenocarcinoma. Int J Oncol 2014;45:2033-43.
20. Lam SK, Li YY, Zheng CY, Ho JC. Downregulation of E2F1 by arsenic trioxide in mesothelioma. Int J Oncol 2015;46:113-22.
21. Liam CK, Andarini S, Lee P, Ho JC, Chau NQ, Tscheikuna J. Lung cancer staging now and in the future. Respirology 2015; doi: 10.1111/resp.12489.
22. Zheng CY, Lam SK, Li YY, Ho JC. Arsenic trioxide-induced cytotoxicity in small cell lung cancer via altered redox homeostasis and mitochondrial integrity. Int J Oncol 2015;46:1067-78.
23. Li YY, Lam SK, Zheng CY, Ho JC. The effect of tumor microenvironment on autophagy and sensitivity to targeted therapy in EGFR-mutated lung adenocarcinoma. J Cancer 2015;6(4):382-386.