Madhusudhanan Narasimhan

Texas Tech University Health Sciences Center, USA

Email: madhu.narasimhan@ttuhsc.edu

Qualifications

1999-2003 Ph.D., University of Madras, Taramani Campus, India

1996-1998 M.Sc., Annamalai University, Chidambaram, India

1993-1996 B. Sc, University of Madras, Chennai, India

Publications(Selected)

1. Mary Rathinam, Lora Watts, Madhusudhanan Narasimhan,Amanjot Riar, Lenin Mahimainathan, George I Henderson. Astrocyte mediated protection of fetal cerebral cortical neurons from rotenone and paraquat. Enivironmental Toxicology and Pharmacology, 33(2),353-360 (2012)
2. Madhusudhanan Narasimhan, Mahimainathan Lenin, Marylatha Rathinam, Amanjot Kaur Riar, George I Henderson. Overexpression of Nrf2 protects cerebral cortical neurons from ethanol-induced apoptotic death.Molecular Pharmacology,80(6),988-999 (2011)
3. Appu Rathinavelu, Madhusudhanan Narasimhan, Praneetha Muthumani. A novel regulation of VEGF expression by HIF-1α and STAT3 in HDM2 transfected prostate cancer cells. Journal of Cellular and Molecular Medicine, (2011)
4. Madhusudhanan Narasimhan,Marylatha Rathinam, Amanjot Kaur, Dhyanesh Patel, Srinivas Mummidi, Hsin-Shen Yang, Nancy H. Colburn, George I Henderson, Lenin Mahimainathan. Programmed Cell Death 4 (PDCD4) Protein : A Novel Player in Ethanol-mediated suppression of protein translation in primary cortical neurons and developing cortex(under reviewAlcoholism : Clinical and Experimental Research)
5. Madhusudhanan Narasimhanand Sudhakar Ammanamanchi. Curcumin blocks RON tyrosine kinase mediated invasion of breast carcinoma cells. Cancer Research,68,5185-5192 (2008)
6. Madhusudhanan Narasimhan,Rajiv Rose,Ramugounder Ramakrishnan, Jason A Zell, Appu Rathinavelu. Identification of HDM2 as a critical regulator of VEGF expression in cancer cells.Life Sciences,82,1231-1241 (2008)
7. Madhusudhanan Narasimhan, Rajiv Rose, Muthusamy Karthikeyan, Appu Rathinavelu. Detection of HDM2 and VEGF Co-expression in Cancer Cell Lines: Novel Effect of HDM2antisense treatment on VEGF Expression.Life Sciences,81,1362-1372 (2007)
8. Megan J Ehret, Gary M Levin,MadhusudhananNarasimhan, Appu Rathinavelu. Venlafaxine Induces P-glycoprotein in Human Caco-2 Cells. Human Psychopharmacology: Clinical and Experimental,22,49-53 (2007)
9. Xudong Yuan, Ling Li, Appu Rathinavelu, Jinsong Hao,Madhusudhanan Narasimhan, Matthew He, Vivene Heitlage, Linda Tam, Sana Viqar, Mojgan Salehi. siRNA drug delivery by biodegradable polymeric nanoparticles.Journal of Nanoscience and Nanotechnology,6,2821-2828 (2006)
10. Madhusudhanan N,KavithaLakshmi S.N, Radha Shanmugasundaram K, Shanmugasundaram E.R.B. Aflatoxin B1induced DNA damage inLabeo rohita:Protective effect of an antioxidant supplement –Amrita Bindu. Basic and Clinical Pharmacology and Toxicology,98,473-479 (2006)
11. Kavithalakshmi S Natarajan*, Madhusudhanan Narasimhan*, K. Radha Shanmugasundaram, E.R.B. Shanmugasundaram. Antioxidant activity of a salt–spice–herbal mixture against free radical induction. Journal of Ethnopharmacology,105,76-83 (2006) (* - Equal contribution)
12. Jayalakshmi Sridhar, Nagaraju Akula, Dakshanamurthy Sivanesan, Madhusudhanan Narasimhan, Appu Rathinavelu, Nagarajan Pattabiraman. Identification of novelangiogenesis inhibitors. Bioorganic and Medicinal Chemistry Letters,15,4125-4129 (2005)
13. R. Vijayaraghavan, C.S. Suribabu, B. Sekar, P.K. Oommen, S.N. Kavithalakshmi,N. Madhusudhananand C. Panneerselvam. Protective role of vitamin E on the oxidative stress in Hansen’s disease (Leprosy) patients.European Journal of Clinical Nutrition,59,1121-1128 (2005)
14. N. Madhusudhanan, S.N. KavithaLakshmi, K. Radha Shanmugasundaram and E.R.B. Shanmugasundaram. Oxidative damage to lipids and proteins induced by aflatoxin B1in fish (Labeo rohita) -protective role ofAmrita Bindu.Environmental Toxicology and Pharmacology,17, 73-77 (2004)
15. Madhusudhanan Narasimhan, Marylatha Rathinam, Dhanashree Vedpathak, Dhyanesh Patel, Amanjot Kaur Riar, Mahimainathan Lenin, George I Henderson. Identification of miRNA groups in synergistic regulation of Nrf2 expression in neuroblastoma(under preparation for Free Radical Biology and Medicine)
16. Madhusudhanan Narasimhan, Marylatha Rathinam, Mahimainathan Lenin, George I Henderson.Pharmacological activation of fetal brain Nrf2/ARE/GSH pathway by maternal administration of sulphoraphane: An attractive option to curtail ETOH-induced fetal neurotoxicity(under preparation for Alcoholism : Clinical and Experimental Research )

Profile Details

Null