Dr. Enming Joseph Su
University of Michigan, USA
Email: bartl@chem.utah.edu
Qualifications
1998 Ph.D., Pathology, University of Washington, USA
1991 B.Sc., Biology, Oral Roberts University, USA
Publications(Selected)
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Su EJ, Geyer M, Wahl M, Mann K, Ginsburg D, Brohmann H, Petersen KU, Lawrence DA. The thrombomodulin analog Solulin promotes reperfusion and reduces infarct volume in a thrombotic stroke model.J Thromb Haemost. 2011 Jun;9(6):1174-82. PMCID: PMC3111949
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Su EJ, Fredriksson L, Schielke GP, Eriksson U, Lawrence DA. Tissue plasminogen activator-mediated PDGF signaling and neurovascular coupling in stroke. J Thromb Haemost, 2009 Jul; 7 Suppl 1:155-8. PMCID: PMC291222
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Hyman MC, Petrovic-Djergovic D, Visovatti SH, Liao H, Yanamadala S, Bouïs D, Su EJ, Lawrence DA, Broekman MJ, Marcus AJ, Pinsky DJ.Self-regulation of inflammatory cell trafficking in mice by the leukocyte surface apyrase CD39.J Clin Invest. 2009;119(5):1136-49. PMCID: PMC2673847
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Su EJ, Fredriksson L, Geyer M, Folestad E, Cale J, Andrae J, Gao Y, Pietras K, Mann K, Yepes M, Strickland DK, Betsholtz C, Eriksson U, Lawrence DA. Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain integrity during ischemic stroke. Nat. Med. 2008;14:731-737. (see commentaries Nat. Med, 2008; 14: 712-713; Science Signaling (Editors' Choice) 2008; 1(28), ec255 Ed (doi:0.1126/scisignal.128ec255); Nature Reviews Drug Discovery, 2008; 7, 643 (doi:10.1038/nrd2642); SciBX: Science–Business eXchange, 2008; 1(23): 1-4.) PMCID: PMC2811427
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Stefansson S, Su EJ, Ishigami S, Cale JM, Gao Y, Gorlatova N, Lawrence DA. The contributions of integrin affinity and intergri-cytoskeletal engagement in endothelial and smooth muscle cell adhesion to vitronectin. J Bio Chem, 2007; 282:15679-15689.
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Leik CE, Su EJ, Nambi P, Crandall DL, Lawrence D.A. Effect of Pharmacologic PAI-1 Inhibition on Cell Motility and Tumor Angiogenesis. J Thromb Haemost. 4:2710-2715, 2006.
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Cao C, Lawrence DA, Li Y, Von ArnimCA, Herz J, Su EJ, Makarova A, Hyman BT, Strickland DK, Zhang L; Endocytic receptor LRP together with tPA and PAI-1 coordinates Mac-1-dependent macrophage migration. EMBO J. 2006 May 3;25(9):1860-70.
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Su EJ, Cioffi CL,Stefansson S, Mittereder N,Garay M, Hreniuk D, Liau G. Gene Therapy Vector-mediated Expression of Insulin-like Growth Factors Protects Cardiomyocytes from Apoptosis and Enhances Neovascularization. Am J Physiol Heart Circ Physiol 2003 Apr 284(4):H1429-40.
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Ancellin N, Colmont C, Su J, Li Q, Mittereder N, Chae SS, Stefansson S, Liau G, Hla T. Extracellular export of sphingosine kinase-1 enzyme. Sphingosine 1-phosphate generation and the induction of angiogenic vascular maturation. J Biol Chem 2002 Feb 22; 277(8):6667-75.
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Liau G, Su EJ, Dixon KD. Clinical efforts to modulate angiogenesis in the adult: gene therapy versus conventional approaches. Drug Discov Today 2001 Jul 1; 6(13): 689-697.
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Su EJ, Stevenson SC, Rollence M, Marshall-Neff J, Liau G: A genetically modified adenoviral vector exhibits enhanced gene transfer of human smooth muscle cells. J Vasc Res 2001 Sep-Oct; 38(5): 471-8.
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Su EJ, Lombardi DM, Wiener J, Daemen MJAP, Reidy MA, Schwartz SM: Mitogenic effect of angiotensin II on rat carotid arteries and type II or III mesenteric microvessels, but not type I mesenteric microvessels, is mediated by endogenous basic fibroblast growth factor. Circ Res. 1998; 82:321-327.
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Su EJ, Lombardi DM, Siegal J, Schwartz SM: Angiotensin II indues smooth muscle replication in the vessel wall independent of blood pressure. Hypertension. 1998; 31(6): 1331-7.
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deBlois D, Lombardi DM, Su EJ, Clowes AW, Schwartz SM, Giachelli CM: Angiotensin II induction of osteopontin expression and DNA replication in rat arteries. Hypertension. 1996; 28:1055-1063.
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deBlois D, Schwartz SM, Van Kleef EM, Su EJ, Griffin KA, Bidani AK, Daemen MJAP, Lombardi DM: Chronic alpha1-adrenoreceptor stimulation increases DNA synthesis in rat arterial wall:modulation of responsiveness after vascular injury. Arteriosclerosis, Thrombosis, and Vascular Biology 1996; 16:1122-1129.