Dr. Mary J. Kelley

Casey EyeInstitute

Oregon Health & Science University, USA

Email: kelleyma@ohsu.edu

Qualifications

Publications (Selected)

1. Kelley, M. J., David, L. L., Iwasaki, N., Wright, J., and Shearer, T.S. α‐Crystallin Chaperone Activity is Reduced by Calpain II in vitro and in Selenite Cataract. (1993) J. Biol. Chem., 268, 18844‐18849.
2. Bradley, J.M.B., Kelley, M.J., Zhu, X.H., Anderssohn, A.M., Alexander, J.P., and Acott, T.S. Effects of Mechanical Stretching on Trabecular Matrix Metalloproteinase Levels. (2001) Invest. Ophthalmol. Vis. Sci., 42, 7, 1505‐1513.
3. Bradley, J.M.B., Kelley, M., Rose, A., and Acott, T.S. Signaling pathways used in trabecular matrix metalloproteinase response to mechanical stretch. (2003) Invest. Ophthalmol. Vis. Sci., 44, 12, 5174‐5181.
4. Vittal, V., Rose, A., Gregory, K., Kelley, M. J., and Acott, T.S. Changes in gene expression by trabecular meshwork cells in response to mechanical stretch. Invest. Ophthalmol. Vis. Sci., 2005, 46: 2857‐2868.
5. Hosseini, M., Rose, A.Y., Song, K., Alexander, J. P., Bohan, C., Kelley, M. J., and Acott, T. S. IL‐1 and TNF induction of matrix metalloproteinase‐3 by c‐Jun N‐terminal kinase in trabecular meshwork. (2006) Invest. Ophthalmol. Vis. Sci., 47: 1469‐76.
6. Kelley, M.J., Rose, A., Song, K., Chen, Y., Bradley, J.M., Rookhuizen, D., and Acott, T.S. Synergism of TNF and IL‐1 in the induction of matrix metalloproteinase‐3 (MMP‐3) in trabecular meshwork. (2007), Invest. Ophthalmol.Vis.Sci., 48: 2634–2643.
7. Kelley, M. J., Rose, A., Lystrup, B., Alexander, J. P., Samples, J. W., and Acott, T. S. p38 MAP Kinase Pathway and Stromelysin Regulation in Trabecular Meshwork Cells.” (2007), Invest. Ophthalmol. Vis. Sci., 48: 3126‐3137.
8. Keller, K., Kelley, M. J., and Acott, T. S. Extracellular matrix gene alternative splicing by trabecular meshwork cells in response to mechanical stretch. (2007) Invest. Ophthalmol. Vis. Sci., 48: 1164‐1172.
9. Aga, M., Bradley, J. M., Keller, K. E., Kelley, M. J., and Acott, T.S. Specialized Podosome‐ or Invadopodia‐ like Structures for Focal Trabecular Meshwork Extracellular Matrix Turnover.(2008) Invest. Ophthalmol. Vis. Sci., 49 (12): 5353‐65.
10. Acott, T.S., Kelley, M.J. Extracellular Matrix in the Trabecular Meshwork. Review. (2008) Exp Eye Res, Vol. 86, 4, 543‐561.
11. Keller, K.E., Bradley, J.M., Kelley, M.J., Acott, T.S. Effects of modifiers of glycosaminoglycan biosynthesis on outflow facility in perfusion culture. (2008) Invest Ophthalmol Vis Sci 49: 2495‐2505.
12. Keller, K.E., Aga, M., Bradley, JM, Kelley, M.J., and Acott, T.S. Extracellular Matrix Turnover and outflow resistance. Exp. Eye Res., 88 (2009) 676‐82.
13. Kelley, M. J., Rose, A.Y., Keller, K.E., Hessle, H., Acott, T.S. Stem Cells in the Trabecular Meshwork: Present and Future Promises. Review . Exp. Eye Res., 88 (2009): 747–751.
14. Acott TS, Keller KE, Kelley MJ, Samples JR. Proteoglycan Biosynthesis and Degradation: What really causes glaucoma? In: The Glaucoma Book, Paul Schacknow, MD, PhD and John Samples, MD; eds., Springer, New York, NY; (2010), 34.2.
15. Acott, T.S., Keller, K.E., and Kelley, M.J. The role of proteoglycans in the trabecular meshwork. In: The Encyclopedia of the Eye, Daart, DA, Besharse, JC, and Dana, R, eds., Ch. 99, (2010) Elsevier, New York, N.Y.; pp.170‐178.
16. Lin, S., Kelley, MJ, and Samples, JR.  Stem Cells in the Trabecular Meshwork. In: The Glaucoma Book, Paul Schacknow, MD, PhD and John Samples, MD; eds. Springer, New York, NY. (2010), p. 951‐952.
17. Anderssohn, A.M., Cox, K., O’Malley, K., Dees, S., Hosseini, M., Boren, L., Wagner, A., Bradley, J.M., Kelley, M. J., Acott, T.S. Molecular Chaperone Function for Myocilin. Invest Ophthalmol Vis Sci 52: 7548‐55, 2011.

Profile Details

https://www.researchgate.net/profile/Mary_Kelley6