Prof. Andrei Surguchov

Email: asurguchov@kumc.edu

Qualifications

Ph.D., Moscow University, Molecular Biology

Publications (Selected)

1. Pronin AN, Morris AJ, Surguchov A,Benovic JL. Synucleins are a novel class of substrates for G protein-coupled receptor kinases. J Biol Chem. 2000 , 275, 26515-26522.
2. A. Surguchov, B. McMahon, E. Masliah, I. Surgucheva. Synucleins in ocular tissues. 2001, J Neurosci Res, 65, 68-77.
3. A. Surguchov,RE. Palazzo, and I. Surgucheva. Gamma synucleins: subcellular localization in neuronal and non-neuronal cells and effect on signal transduction. Cell Motility and Cytoskeleton, 2001, 49, 218-228.
4. Surgucheva I., McMahan B, F. Ahmed , Tomarev S, Wax MB,Surguchov A. 2002. Synucleins in glaucoma. J Neurosci Res, 68: 97-106.
5. Surgucheva I, Sivak, JM, Fini ME, Palazzo RE andSurguchov AP.2003.Effect of gamma-synuclein overexpression on matrix metalloproteinases in retinoblastoma Y79 cells. Arch Biochem Biophys. 410: 167-176.
6. Maurage CA, Ruchoux MM, De Vos R,Surguchov A, Destee A. 2003. Retinal involvement in dementia with Lewy bodies: A clue to hallucinations? Ann Neurol. 54(4): 542-7.
7. Snyder HM, Mensah K, Surgucheva I, Festoff B,Surguchov A,Wolozin B.b-Synuclein prevents Proteasomal inhibition by α-synuclein but not γ-synuclein. J Biol Chem, 2005. 4; 280: 7562-9.
8. Surgucheva, B. Yue, BC Park, S Tomarev andA. Surguchov.2005. Interaction of myocilin with γ-synuclein and its role in neurodegeneration in glaucoma. Cellular Molecular Neurobiology, 25, 6, 1009-1033.
9. Surgucheva I, Ninkina N, Buchman VL, Grasing K,A. Surguchov. 2005. Protein aggregation in retinal cells and approaches to cell protection. Cellular Molecular Neurobiology, 25, 6, 1051-1066.
10. Surgucheva I, McMahon B.,A. Surguchov. 2006. Dynamic intracellular localization of -synuclein: a clue to its functions. Cell Motility and Cytoskeleton, 63, 8, 447-458.
11. Surgucheva I, Surguchov A.2008. -Synuclein: Cell-Type Specific Promoter Activity and Binding to Transcription Factors. J Mol Neuroscience, 2008; 35(3): 267-71.
12. A. Surguchov. 2008. Molecular and cellular biology of synucleins. Internat Review of Cell and Mol Biol, 270, 225-317.
13. I Surgucheva, AShnyra, J Goldberg, A. Weisman andA Surguchov. 2008. Synuclein is a marker of theretinal ganglion cells, Molecular Vision, 14: 1540-1548.
14. I Surgucheva, V Shestopalov andA Surguchov.2008. Effect of -synuclein silencing on apoptotic pathways in retinal ganglion cells. J Biol Chem, v. 284, (52): 36377-85.
15. A. Surguchev andA. Surguchov.2010. Conformational Diseases: Looking into the eyes. Brain Research Bull, 81, pp. 12-24.
16. Surgucheva I, Chidambaram K, Willoughby DA,Surguchov A. MicroRNA regulates MMP-9 expression. J Ocular Biology, Diseases and Bioinformatics 2010; 3: 41-52,
17. Surgucheva I, McMahon B,Surguchov A.Patterns of synuclein expression throughout lens development. J BiophysChem 2010; 1: 12-18.
18. Surguchov A. in “Protein Aggregation” (Editor: DA. Stein). Folding and unfolding of Synucleins.Nova Science Publishers, 2011.
19. Surgucheva I and Surguchov A.Expression of caveolins in trabecular meshwork cells and its possible implication in pathogenesis of primary open angle glaucoma. Molecular Vision 2011; 17: 2878-2888.

Profile Details

Last Updated: August, 2012.