Prof. Luigi Iuliano
Department of Medico-Surrgiacl Sciences and Biotechnology (MSSB)

Sapienza University of Rome, Italy


2006 Affiliated external Professor, Charles University in Prague, Czech Republic
2001 Associate Professor of Internal Medicine
1996-1998 visiting Scientist, Center of Experimental Therapeutics, University of Pennsylvania, School of Medicine Philadelphia, diretto dal Prof. Garret A. FitzGerald
1987 Board Certification in Internal Medicine, cum Laude. Sapienza University in Rome
1982-1987 Fellowship, Division of Internal Medicine and Atherothrombosis Unit, Policlinico Umberto I Hospital of La Sapienza University in Rome
1982 Degree in Medicine, cum Laude. Sapienza University in Rome

1977-1982 Internal student, Department of Internal Medicine, Sapienza University in Rome

Publications (Selected)
  1. IulianoL (2011) Pathways of cholesterol oxidation via non-enzymatic mechanisms. Chem Phys Lipids 164, 457-468.
  2. Schmitz G, Lizard G, Iuliano L (2010) Special issue to LipidomicNet and ENOR joint Workshop (19-20 November 2010; Munich, Germany) "Analysis and function of oxysterols and other regulatory and lipotoxic molecular lipid species". Chem Phys Lipids 164, 409-410.
  3. Iuliano L, Misuraca M, Varroni A, Raponi M, Massucci M, Pagnanelli A, Cimino G, Bertoletti G (2011) Multiple thromboembolism with multiple causes in a 69-year-old woman: a case report. J Med Case Reports 5, 186.
  4. GalliF, Iuliano L (2010) Do statins cause myopathy by lowering vitamin E levels? Med Hypotheses 74, 707-709.
  5. Anticoli S, Arciello M, Mancinetti A, De Martinis M, Ginaldi L, Iuliano L, Balsano C (2010) 7-ketocholesterol and 5,6-secosterol modulate differently the stress-activated mitogen-activated protein kinases (MAPKs) in liver cells. J Cell Physiol 222, 586-595.
  6. Napoli A, Catalano C, Francone M, Sciacca V, Carbone I, Greco C, Anzidei M, Calabrese FA, Marincola BC, Kirchin MA, Vestri A, Arca M, Iuliano L, Passariello R (2009) Imaging coronary and extracoronary atherosclerosis: feasibility and impact of whole-body computed tomography angiography. Eur Radiol 19, 1704-1714.
  7. Iuliano L, Monticolo R, Straface G, Zullo S, Galli F, Boaz M, Quattrucci S (2009) Association of cholesterol oxidation and abnormalities in fatty acid metabolism in cystic fibrosis. Am J Clin Nutr 90, 477-484.
  8. Iuliano L, Micheletta F, Napoli A, Catalano C (2009) Myocardial infarction with normal coronary arteries: a case report and review of the literature. J Med Case Reports 3, 24.
  9. Iuliano L, Di Matteo A, Straface G (2009) Management of nonvalvular atrial fibrillation: a comprehensive approach. Indian J Med Sci 63, 419-430.
  10. Biscetti F, Straface G, Arena V, Stigliano E, Pecorini G, Rizzo P, De Angelis G, Iuliano L, Ghirlanda G, Flex A (2009) Pioglitazone enhances collateral blood flow in ischemic hindlimb of diabetic mice through an Akt-dependent VEGF-mediated mechanism, regardless of PPARgamma stimulation. Cardiovasc Diabetol 8, 49.
  11. Francone M, Di Castro E, Napoli A, Bolzan C, Carbone I, Bertoletti L, Iuliano L, Catalano C, Passariello R (2008) Dose reduction and image quality assessment in 64-detector row computed tomography of the coronary arteries using an automatic exposure control system. J Comput Assist Tomogr 32, 668-678.
  12. Larsson H, Bottiger Y, Iuliano L, Diczfalusy U (2007) In vivo interconversion of 7 beta-hydroxycholesterol and 7-ketocholesterol, potential surrogate markers for oxidative.
  13. IulianoL, Micheletta F, Natoli S, Tramaglino L, Greco C, Modesti PA (2007) Aortic coarctation in the elderly: how many errors lie behind an unexpected diagnosis? Intern Emerg Med 2, 207-209.
  14. Arca M, Natoli S, Micheletta F, Riggi S, Di Angelantonio E, Montali A, Antonini TM, Antonini R, Diczfalusy U, Iuliano L (2007) Increased plasma levels of oxysterols, in vivo markers of oxidative stress, in patients with familial combined hyperlipidemia: reduction during atorvastatin and fenofibrate therapy. Free Radic Biol Med 42, 698-705.
  15. MichelettaF, Natoli S, Iuliano L (2005) Implantable cardioverter-defibrillator therapy after myocardial infarction. N Engl J Med 352, 1039-1041; author reply 1039-1041.
  16. Corradini SG, Micheletta F, Natoli S, Iappelli M, Di Angelantonio E, De Marco R, Elisei W, Siciliano M, Rossi M, Berloco P, Attili AF, Diczfalusy U, Iuliano L (2005) High preoperative recipient plasma 7beta-hydroxycholesterol is associated with initial poor graft function after liver transplantation.Liver Transpl 11, 1494-1504.
  17. Boaz M, Iuliano L, Himmelfarb J, Matas Z, Micheletta F, McMonagle E, Friedman V, Natoli S, Gvirtz G, Biro A, Smetana S, Sabo G, Gafter U, Weinstein T (2005) Baseline oxysterols and other markers of oxidative stress, inflammation and malnutrition in the vitamin e and intima media thickness progression in end-stage renal disease (VIPER) cohort.Nephron Clin Pract100, c111-119.
  18. Micheletta F, Natoli S, Misuraca M, Sbarigia E, Diczfalusy U, Iuliano L (2004) Vitamin E supplementation in patients with carotid atherosclerosis: reversal of altered oxidative stress status in plasma but not in plaque. Arterioscler Thromb Vasc Biol 24, 136-140.
  19. Iuliano L, Micheletta F, Natoli S, Ginanni Corradini S, Iappelli M, Elisei W, Giovannelli L, Violi F, Diczfalusy U (2003) Measurement of oxysterols and alpha-tocopherol in plasma and tissue samples as indices of oxidant stress status. Anal Biochem 312, 217-223.
  20. IulianoL, Micheletta F, Natoli S (2003) Bullous pemphigoid: an unusual and insidious presentation of breast cancer. ClinOncol (R Coll Radiol) 15, 505.
  21. VioliF, Micheletta F, Iuliano L (2002) How to select patient candidates for antioxidant treatment? Circulation106, e195; author reply e195.
  22. VioliF, Micheletta F, Iuliano L (2002) MRC/BHF Heart Protection Study. Lancet 360, 1782-1783; author reply 1783-1784.
  23. Silvestro A, Scopacasa F, Oliva G, de Cristofaro T, Iuliano L, Brevetti G (2002) Vitamin C prevents endothelial dysfunction induced by acute exercise in patients with intermittent claudication. Atherosclerosis 165, 277-283.
  24. Iuliano L, Micheletta F, Violi F, Spagnoli LG (2002) Effect of ramipril and vitamin E on atherosclerosis. Circulation 105, E5-6.
  25. Ferro D, Iuliano L, Violi F, Valesini G, Conti F (2002) Antioxidant treatment decreases the titer of circulating anticardiolipin antibodies: comment on the article by Sambo et al.
  26. VioliF, Micheletta F, Iuliano L (2001) Vitamin E, atherosclerosis and thrombosis. Thromb Haemost 85, 766-770.
  27. VioliF, Micheletta F, Iuliano L (2001) Vitamin E supplementation. Lancet357, 632-633.
  28. VioliF, Micheletta F, Iuliano L (2001) Clinical trials with vitamin E in cardiovascular disease: are they meaningful? Thromb Haemost 86, 1121-1122.
  29. IulianoL, Pratico D, Greco C, Mangieri E, Scibilia G, FitzGerald GA, Violi F (2001) Angioplasty increases coronary sinus F2-isoprostane formation: evidence for in vivo oxidative stress during PTCA.J Am Coll Cardiol37, 76-80.
  30. IulianoL, Micheletta F, Violi F (2001) Low-density lipoprotein oxidation. Ital Heart J2, 867-872.
  31. IulianoL, Micheletta F, Maranghi M, Frati G, Diczfalusy U, Violi F (2001) Bioavailability of vitamin E as function of food intake in healthy subjects: effects on plasma peroxide-scavenging activity and cholesterol-oxidation products. Arterioscler Thromb Vasc Biol21, E34-37.
  32. IulianoL, Micheletta F (2001) [Atrial fibrillation. Epidemiology and physiopathology.]. Haematologica 86, 1-4.
  33. IulianoL, Gurgo A, Pranteda G (2001) Guess what! Malignant metastatic melanoma presenting with generalized melanosis and melanuria. EurJ Dermatol 11, 477-478.
  34. IulianoL (2001) The oxidant stress hypothesis of atherogenesis. Lipids3 6 Suppl, S41-44.
  35. IulianoL (2001) Antioxidant therapy in vascular disease. Haematologica 86, 22-24.
  36. Iuliano L, Monticolo R, Straface G, Spoletini I, Gianni W, Caltagirone C, Bossu P, Spalletta G (2010) Vitamin E and Enzymatic/Oxidative Stress-Driven Oxysterols in Amnestic Mild Cognitive Impairment Subtypes and Alzheimer's Disease. J Alzheimers Dis.
  37. Straface G, Biscetti F, Pitocco D, Bertoletti G, Misuraca M, Vincenzoni C, Snider F, Arena V, Stigliano E, Angelini F, Iuliano L, Boccia S, de Waure C, Giacchi F, Ghirlanda G, Flex A (2011) Assessment of the Genetic Effects of Polymorphisms in the Osteoprotegerin Gene, TNFRSF11B, on Serum Osteoprotegerin Levels and Carotid Plaque Vulnerability. Stroke 2011 Nov; 42(11): 3022-8.
  38. Pigna G, Napoli A, Zaccagna F, Marincola BC, Monticolo R, Catalano C, Iuliano L, Arca M (2011) The relationship between metabolic syndrome, its components, and the whole-body atherosclerotic disease burden as measured by computed tomography.
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