Biography

Dr. Hiromitsu Tanaka
Cedars-Sinai Medical Center
Nagasaki International University, Japan

Email: h-tanaka@niu.ac.jp

Qualifications

2008 Associate professor of Department of Molecular Biology, Nagasaki International University, Japan
1990-1993 Ph.D., Department of Molecular Biology, Kyoto Pharmaceutical University, Japan
1987-1989 B.Sc., Department of Biology, Osaka City University, Japan
1983-1987 M.Sc., Education Research Department, Osaka Kyoiku University, Japan


Publications

  1. Irie S, Nakamura J, Miyagawa Y, Tsujimura A, Okuda H, Yamamoto K, Fukuhara S, Yoshioka I, Hiroshi K, Matsuoka Y, Takao T, Nonomura N, Ikawa M, Tokuhiro K, Okabe M, Shibata T, Fujimoto K, Wada M, Tanaka H. The Open Androl J. (in press).
  2. Takahashi H, Tainaka H, Umezawa M, Takeda K, Tanaka H, Nishimune Y, Oshio S. Evaluation of testicular toxicology of doxorubicin based on microarray analysis of testicular specific gene expression. J Toxicol Sci.36:559-567 (2011).
  3. Nagai M, Moriyama T, Mehmood R, Tokuhiro K, Ikawa M, Okabe M, Tanaka H, Yoneda Y. Mice lacking Ran binding protein 1 are viable and show male infertility. FEBS Lett 585:791-796 (2011).
  4. Irie S, Nakamura J, Tsujimura A, Miyagawa Y, Tanaka H. Single Nucleotide Polymorphisms of the IZUMO Gene in Male Infertile Patients. Nagasaki Int. Univ. Rev.10:209-218.
  5. Tokuhiro K, Isotani A, Yokota S, Yano Y, Oshio S, Hirose M, Wada M, Fujita K, Ogawa Y, Okabe M, Nishimune Y, Tanaka H. OAZ-t/OAZ3 is essential for rigid connection of sperm tails to heads in mouse. PLoS Genet. 5: e1000712.
  6. Ueda T, Manabe H, Keizo T, Hirose M, Matsuoka Y, Miyagawa Y, Tsujimura A, Fujita K, Wada M, Okuyama A, Tanaka H.Unique expression of encoding an acrosomal protein (ACPIN1) and salivary-specific protein (SAGSIN1) alternatively translated from two open reading frames on Acpin1 mRNA. Int. J. Urol.16:639-646.
  7. Irie S, Tsujimura A, Miyagawa Y, Ueda T, Matsuoka Y, Matsui Y, OkuyamaA, Nishimune Y, Tanaka H.Single Nucleotide Polymorphisms in PRDM9 (MEISETZ) in Patients with Nonobstructive Azoospermia. J Androl..30:426-431.
  8. Ueda T, Miyagawa Y, Tsujimura A, Okuyama A, Tanaka H. Cloning and Characterization of a novel gene ACPIN1 Med J. Osaka Univ. 52:27-41.
  9. Tokuhiro K, Miyagawa Y, Tanaka H. Characterizing mouse male germ cell-specific actin capping protein a3 (cpα3): Dynamic patterns of expression in testicular and epididymal sperm. Asian J Andrology 10:711-718.
  10. Tokuhiro K, Hirose M, Miyagawa Y, Tsujimura A, Irie S, Isotani A,Okabe M, Toyama Y, Ito C, Toshimori K, Takeda K, Oshio S, Tainaka H, Tsuchida J, Okuyama A, Nishimune Y, Tanaka H. Meichroacidin containing the MORN motif is essential for spermatozoa morphogenesis. J Biol Chem 283:19039-19048.
  11. Matsuoka Y, Miyagawa Y, Tokuhiro K, Kitamura K, Iguchi N, Maekawa M, Takahashi T, Tsujimura A, Matsumiya K, Okuyama A, Nishimune Y, Tanaka H. Isolation and Characterization of the Haploid Germ Cell-Specific Smrp1 Gene for a Novel Manchette Protein in the Mouse. Mol Reprod Dev 75:967-975.
  12. Yamada K, Akiyama N, Yamada S, Tanaka H, Saito S, Hiraoka M, Kizaka-Kondoh S. Taip2 is a novel cell death-related gene expressed in the brain during development. Biochem Biophys Res Commun 369:426-431.
  13. Tanaka H, Hirose M, Tokuhiro K, Tainaka H, Miyagawa Y, Tsujimura A, Okuyama A, Nishimune Y. Molecular biological features of male germ cell differentiation. Reprod Med Biol 6 1-9.
  14. Ike A, Tokuhiro K, Hirose M, Nozaki M, Nishimune Y, Tanaka H. Comprehensive analysis of gene expression in testes producing haploid germ cells using DNA microarray analysis. Int J Androl 30:462-475.
  15. Tokuhiro K, Miyagawa Y, Yamada S, Hirose M, Ohta H, Nishimune Y, Tanaka H. The 193-Base Pair Gsg2 (Haspin) Promoter Region Regulates Germ Cell-Specific Expression Bidirectionally and Synchronously. Biol Reprod 76:407-414.
  16. Kita K, Watanabe T, Ohsaka K, Hayashi H, Kubota Y, Nagashima Y, Aoki I, Taniguchi H, Noce T, Inoue K, Miki H, Ogonuki N, Tanaka H, Ogura A, Ogawa T. Production of Functional Spermatids from Mouse Germline Stem Cells in Ectopically Reconstituted Seminiferous Tubules. Biol Reprod 76:211-217


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