Prof. Carlos Martínez-A.

Dept. of Immunology and Oncology, Centro Nacional de Biotecnología

Universidad Autónoma, Spain





1978   Ph.D., Clínica Puerta de Hierro, Madrid and Univ. Complutense, Spain
1974   B.Sc., Universidad Complutense, Spain
1970   Secondary school, Universidad Laboral de Alcalá de Henares, Spain



  1. Martínez-A C, RR Bernabé, P Pereira, A de la Hera, C Márquez, PA Cazenave and A Coutinho. Idiotypic helper T-cell repertoires are established early in life. Nature 317: 721-723, 1985 
  2. P. Pereira, A. Bandeira, A. Coutinho, M.A.R. Marcos, M.L. Toribio and C. Martínez -A. Vregion connectivity in T-cell repertoires. Ann. Rev.Immunol. 7: 209, 1989 
  3. Martínez-A C and A Coutinho. B-cell activation by helper cells is a two-step process. Nature 290, 60-61, 1981 
  4. Toribio ML, JC Gutierrez-Ramos, L Pezzi, MAR Marcos and C Martínez-A. Interleukin-2-dependent autocrine proliferation in T-cell development. Nature 342: 82-85, 1989 
  5. G. Kroemer and C. Martínez-A. The fail-safe paradigm of immunological tolerance: Conceptual and clinical implications. Lancet 338, 1246, 1991 
  6. Balomenos D, J Martín-Caballero, MI García, I Prieto, JM Flores, M Serrano & C Martínez-A. The cell cycle inhibitor p21 controls T cell proliferation and sex-linked lupus development. Nature Med 6, 171-176, 2000 
  7. Álvarez B, C Martínez-A, BMT Burgering & AC Carrera. Forkhead transcription factors contribute to execution of the mitotic program in mammals. Nature 413, 744-747, 2001 
  8. Mellado M, JMR Frade, S Mañes & C Martínez-A. Chemokine signaling and functional responses: the role of receptor dimerization and TK pathway activation. Annu Rev Immunol 19, 397-421, 2001 
  9. Mañes S, G del Real & C Martínez-A. Pathogens: raft hijackers. Nature Rev Immunol 3, 557-562, 2003 
  10. Hernanz-Falcón P, A Serrano, JM Rodriguez-Frade, D Juan, A del Sol, SF Soriano, F Roncal, L Gómez, A Valencia, C Martínez-A & M Mellado. Identification of amino acid residues critical for CCR5 dimerization. Nature Immunol 5, 216-223, 2004 
  11. Molon B, G Gri, M. Bettella, C Gómez-Moutón, A Lanzavecchia, C Martínez-A, S Mañes and A Viola. T cell costimulation by chemokine receptors. Nature Immunol. 6, 427-431, 2005 
  12. Jimenez-Baranda, S., Gomez-Mouton, C., Rojas, A., Martinez-Prats L., Mira, E., Lacalle, R., Valencia A., Dimitrov, D., Viola, A., Delgado, R., Martinez-A. C., and Mañes S. Filamin regulates actin-dependent clustering of HIV.1 receptors and cell infection. Nature Cell Biology, 9 (7) 838-847, 2007 
  13. Mercader N, E Leonardo, N Azpiazu, A Serrano, G Morata, C Martínez-A & M Torres. Conserved role of Meis1/Hth in specification of the proximodistal limb axis. Nature 402: 425-429, 1999. 
  14. D. García-Domingo, E. Leonardo, A. Grandien, P. Martínez, J P. Albar, J. C. Izpisúa- Belmonte and C. Martínez-A. Dido is a gene involved in onset of apoptosis in vitro, whose misexpression disrupts limb development. Proc. Natl. Acad. Sci. USA 96, 7992-7997, 1999. 
  15. Trachana, V., van Welly, K., Alonso Guerrero, A., Futterer, A. and Martinez-A. C.. Dido disruption leads to centrosome amplification and mitotic checkpoint defects compromising chromosome stability. Proc. Natl. Acad. Sci. USA, 104, 2691-2696, 2007. 
  16. Alonso Guerrero A, Cano Gomero M, Trachana V, Futterer A, Pacios-Bras C, Cigudos JC, Martínez-A C, van Wely KH Centromere-localized breaks indicate the generation of DNA damage by the mitotic spindle. Proc Natl Acad Sci USA, 107, 4159-4164, 2010.

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Last Updated: December 15, 2011.

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