Dr. Iryna M. Ethell
Biomedical Sciences, University of California, USA
Associate Professor
Email: iryna.ethell@ucr.edu
Qualifications
1991 Ph.D., Biochemistry, Dnipropetrovsk National University, Ukraine
1988 B.S., Biochemistry, Dnipropetrovsk National University, Ukraine
Publications
- Sloniowski S, Ethell IM. 2011. Looking forward to EphB signaling in synapses. Seminars in Cell and Dev Biol. In press.
- Dansie L, Ethell IM. 2011. Casting a net on dendritic spines: The extracellular matrix and its receptors. Dev Neurobiol. 71(11): 956-981.
- Cesa R, Premoselli F, Renna A, Ethell IM, Pasquale EB, Strata P. 2011. Eph receptors are involved in the activity-dependent synaptic wiring in the mouse cerebellar cortex. PLoS One. 6(4):e19160.
- Paribello C, Tao L, Folino A, Berry-Kravis E, Tranfaglia M, Ethell IM, Ethell DW. 2010. Open-label add-on treatment trial of minocycline in fragile X syndrome. BMC Neurol. Oct 11: p10:91.
- Utari, A., Chonchaiya, W., Rivera, S.M., Schneider, A., Hagerman, R.J., Faradz, S.M., Ethell, I.M., Nguyen, D.V. 2010. Side effects of minocycline treatment in patients with fragile x syndrome and exploration of outcome measures. Am J Intellect Dev Disabil. Vol. 115(5): p433-443.
- Yang NY, Lopez-Bergami P, Goydos JS, Yip D, Walker AM, Pasquale EB, Ethell IM. 2010. The EphB4 receptor promotes the growth of melanoma cells expressing the ephrin-B2 ligand. Pigment Cell Melanoma Res. 23(5):684-687.
- C. Pontrello and I. M. Ethell 2009. Accelerators, brakes, and gears of actin dynamics in dendritic spines. TONJ, 3: 67-86.
- Y. Shi, C. Pontrello, K. Defea, L.F. Reichardt and I. M. Ethell 2009. Focal adhesion kinase acts downstream of EphB receptors to maintain mature dendritic spines by regulating cofilin activity. J. Neurosci., 29(25): 8075-8086.
- T. Bilousova, L. Dansie, M. Ngo, J. Aye, J. R. Charles, D.W. Ethell and I. M. Ethell 2009. Minocycline Promotes Dendritic Spine Maturation and Improves Behavioral Performance in the Fragile X Mouse Model. J Med Gen., 46(2):94-102. Epub 2008 Oct 3.
- K.-T. Lin, D.W. Ethell and I.M. Ethell 2008 Ephrin-B2-induced cleavage of EphB2 receptor is mediated by matrix metalloproteinases to trigger cell repulsion. J Biol Chem, 283(43):28969-28979. Epub 2008 Aug 19.
- I.M. Ethell and D.W. Ethell 2007. Matrix Metalloproteinases in Brain Development and Remodeling: Synaptic Functions and Targets. J. Neurosci. Res. 85(13):2813-2823.
- T. Bilousova, D. Rusakov, D.W. Ethell and I.M. Ethell 2006. MMP-7 Disrupts Dendritic Spines in Hippocampal Neurons through NMDA Receptor Activation. J. Neurochem. 97(1):44-56. Epub 2006 Mar 3.
- Y. Shi and I.M. Ethell 2006. Integrins Control Dendritic Spine Plasticity in Hippocampal Neurons through NMDA Receptor and CaMKII-Mediated Actin Reorganization. J. Neurosci. 26(6):1813-1822.
- M.L. Moeller, Y. Shi, L.F. Reichardt and I.M. Ethell 2006. EphB receptors regulate dendritic spine morphogenesis through the recruitment/phosphorylation of FAK and RhoA activation. J Biol Chem. 281(3):1587-98. Epub 2005 Nov 18.
- C.C. Hoogenraad, A.D. Milstein, I.M. Ethell, M. Henkemeyer and M. Sheng 2005. GRIP1 controls dendrite morphogenesis by regulating EphB receptor trafficking. Nat Neurosci. 8(7):906-915.
- I.M. Ethell and E.B. Pasquale 2005. Molecular mechanisms of dendritic spine development and remodeling. Prog Neurobiol. 75(3):161-205. Epub 2005 Apr 2.
- M. Henkemeyer, O.S. Itkis, M. Ngo, P.W. Hickmott and I.M. Ethell 2003. Multiple EphB receptor tyrosine kinases shape dendritic spines in the hippocampus. J Cell Biol., 163(6):1313-1326.
- I.M. Ethell, F. Irie, M.S.Kalo, J.R.Couchman, E.B. Pasquale and Y. Yamaguchi 2001. EphB2/syndecan-2 signaling in dendritic spine morphogenesis. Neuron, 31: 1001-1013.
- H.-G. Wang, N. Pathan, I.M. Ethell, S. Krajewski, Y. Yamaguchi, F. Shibasaki, F. McKeon, T. Bobo, T.F. Franke and J. Reed 1999. Ca-Induced apoptosis through calcineurin dephosphorylation of BAD. Science 284: 339-343.
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