Biography

Dr. Iryna M. Ethell

Biomedical Sciences, University of California, USA

Associate Professor 


Email:
iryna.ethell@ucr.edu

 

Qualifications

1991   Ph.D., Biochemistry, Dnipropetrovsk National University, Ukraine
1988   B.S., Biochemistry,
Dnipropetrovsk National University, Ukraine  
 

Publications

  1. Sloniowski S, Ethell IM. 2011. Looking forward to EphB signaling in synapses. Seminars in Cell and Dev Biol. In press. 
  2. Dansie L, Ethell IM. 2011. Casting a net on dendritic spines: The extracellular matrix and its receptors. Dev Neurobiol. 71(11): 956-981. 
  3. Cesa R, Premoselli F, Renna A, Ethell IM, Pasquale EB, Strata P. 2011. Eph receptors are involved in the activity-dependent synaptic wiring in the mouse cerebellar cortex. PLoS One. 6(4):e19160. 
  4. Paribello C, Tao L, Folino A, Berry-Kravis E, Tranfaglia M, Ethell IM, Ethell DW. 2010. Open-label add-on treatment trial of minocycline in fragile X syndrome. BMC Neurol. Oct 11: p10:91.  
  5. Utari, A., Chonchaiya, W., Rivera, S.M., Schneider, A., Hagerman, R.J., Faradz, S.M., Ethell, I.M., Nguyen, D.V. 2010. Side effects of minocycline treatment in patients with fragile x syndrome and exploration of outcome measures. Am J Intellect Dev Disabil. Vol. 115(5): p433-443. 
  6. Yang NY, Lopez-Bergami P, Goydos JS, Yip D, Walker AM, Pasquale EB, Ethell IM. 2010. The EphB4 receptor promotes the growth of melanoma cells expressing the ephrin-B2 ligand. Pigment Cell Melanoma Res. 23(5):684-687.  
  7. C. Pontrello and I. M. Ethell 2009. Accelerators, brakes, and gears of actin dynamics in dendritic spines. TONJ, 3: 67-86. 
  8. Y. Shi, C. Pontrello, K. Defea, L.F. Reichardt and I. M. Ethell 2009. Focal adhesion kinase acts downstream of EphB receptors to maintain mature dendritic spines by regulating cofilin activity. J. Neurosci., 29(25): 8075-8086. 
  9. T. Bilousova, L. Dansie, M. Ngo, J. Aye, J. R. Charles, D.W. Ethell and I. M. Ethell 2009. Minocycline Promotes Dendritic Spine Maturation and Improves Behavioral Performance in the Fragile X Mouse Model. J Med Gen., 46(2):94-102. Epub 2008 Oct 3. 
  10. K.-T. Lin, D.W. Ethell and I.M. Ethell 2008 Ephrin-B2-induced cleavage of EphB2 receptor is mediated by matrix metalloproteinases to trigger cell repulsion. J Biol Chem, 283(43):28969-28979. Epub 2008 Aug 19. 
  11. I.M. Ethell and D.W. Ethell 2007. Matrix Metalloproteinases in Brain Development and Remodeling: Synaptic Functions and Targets. J. Neurosci. Res. 85(13):2813-2823. 
  12. T. Bilousova, D. Rusakov, D.W. Ethell and I.M. Ethell 2006. MMP-7 Disrupts Dendritic Spines in Hippocampal Neurons through NMDA Receptor Activation. J. Neurochem. 97(1):44-56. Epub 2006 Mar 3. 
  13. Y. Shi and I.M. Ethell 2006. Integrins Control Dendritic Spine Plasticity in Hippocampal Neurons through NMDA Receptor and CaMKII-Mediated Actin Reorganization. J. Neurosci. 26(6):1813-1822. 
  14. M.L. Moeller, Y. Shi, L.F. Reichardt and I.M. Ethell 2006. EphB receptors regulate dendritic spine morphogenesis through the recruitment/phosphorylation of FAK and RhoA activation. J Biol Chem. 281(3):1587-98. Epub 2005 Nov 18. 
  15. C.C. Hoogenraad, A.D. Milstein, I.M. Ethell, M. Henkemeyer and M. Sheng 2005. GRIP1 controls dendrite morphogenesis by regulating EphB receptor trafficking. Nat Neurosci. 8(7):906-915.
  16. I.M. Ethell and E.B. Pasquale 2005.  Molecular mechanisms of dendritic spine development and remodeling. Prog Neurobiol. 75(3):161-205. Epub 2005 Apr 2. 
  17. M. Henkemeyer, O.S. Itkis, M. Ngo, P.W. Hickmott and I.M. Ethell 2003.  Multiple EphB receptor tyrosine kinases shape dendritic spines in the hippocampus. J Cell Biol., 163(6):1313-1326. 
  18. I.M. Ethell, F. Irie, M.S.Kalo, J.R.Couchman, E.B. Pasquale and Y. Yamaguchi 2001. EphB2/syndecan-2 signaling in dendritic spine morphogenesis. Neuron, 31:  1001-1013. 
  19. H.-G. Wang, N. Pathan, I.M. Ethell, S. Krajewski, Y. Yamaguchi, F. Shibasaki, F. McKeon, T. Bobo, T.F. Franke and J.  Reed 1999. Ca-Induced apoptosis through calcineurin dephosphorylation of BAD. Science 284: 339-343.
     

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Last Updated: December 9, 2011.

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