Prof. Arun K. Bhunia
Department of Food
Science
Department of
Comparative Veterinary Pathobiology
Purdue Institute
of Inflammation, Immunology, and Infectious Diseases
Purdue University
West Lafayette,
IN, USA
Email: bhunia@purdue.edu
Qualifications
1995 Postdoctoral
Training, University of Arkansas, Fayetteville, AR, USA
1989 Ph.D., University of Wyoming, Laramie, USA
1984 Bachelor of Veterinary Science (equivalent to DVM), WBUAFS, India
Publications (Selected)
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Bai, X., Liu, D., Xu, L., Drolia, R.,
Gallina, L.F., Cox, A.D., and Bhunia, A.K. 2021. Biofilm-isolated Listeria
monocytogenes exhibits reduced systemic dissemination at the early (12-24 h)
stage of infection in a mouse model. Npj Biofilm and Microbiome 7:18
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Ryan, V.E., Taylor W. Bailey, Liu, D., T.W.,
Vemulapalli, T., Cooper, B., Durkes, A.C., and Bhunia, A.K. 2021. Listeria
adhesion protein-expressing bioengineered probiotics prevent fetoplacental
transmission of Listeria monocytogenes in a pregnant guinea pig model.
Microbial Pathogenesis 151:104752
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Drolia, R., Amalaradjou, M.A.R., Ryan, V.E.,
Tenguria, S., Liu, D., Bai., X., Xu, L., Singh, A.K., Cox, A.D., Bernal-Crespo,
V., Schaber, J.A., Applegate, B.M., Vemulapalli, R., and Bhunia, A.K. 2020.
Receptor-targeted engineered probiotics mitigate lethal Listeria infection.
Nature Communications 11:6344.
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Xu, L., Bai, X., Tenguria, S., Liu, Y.,
Drolia, R., and Bhunia, A.K. 2020. Mammalian cell-based immunoassay for
detection of viable bacterial pathogens. Frontiers in Microbiology 11:575615
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Drolia, R., and Bhunia, A.K. 2019. Crossing
the Epithelial Barrier via Listeria Adhesion Protein and Internalin A, Trends
in Microbiology 27 (5): 408-425.
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Mathipa, M., Thantsha, M.S., and Bhunia,
A.K., 2019. Lactobacillus casei expressing internalins A and B reduces Listeria
monocytogenes interaction with Caco-2 cells in vitro. Microbial Biotechnology
12(4):715-729.
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Drolia, R., Tenguria, S., Durkes, A.C.,
Turner, J.R. and Bhunia, A.K. 2018. Listeria Adhesion Protein Induces
Intestinal Epithelial Barrier Dysfunction for Bacterial Translocation. Cell
Host & Microbe 23(4): 470-480.e7.
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Zhu, X., Liu, D., Singh, A.K., Drolia, R.,
Bai, X., Tenguria, S., and Bhunia, A.K. 2018. Tunicamycin mediated inhibition
of wall teichoic acid affect Staphylococcus aureus and Listeria monocytogenes
cell morphology, biofilm formation and virulence. Frontiers in Microbiology
9:1352.
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Koo, O.K., Amalaradjou, M.A.R., and Bhunia,
A.K. 2012. Recombinant probiotic expressing Listeria adhesion protein
attenuates Listeria monocytogenes virulence in vitro. PLoS One 7 (1):e29277.
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Jagadeesan, B., Fleishman Littlejohn, A.E.,
Amalaradjou, M.A.R., Singh, A.K., Mishra, K., La, D., Kihara, D., and Bhunia,
A.K. 2011. N-terminal Gly224–Gly411 domain in Listeria Adhesion Protein
interacts with host receptor Hsp60. PLoS ONE 6 (6):e20694.
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Burkholder, K.M. and Bhunia, A.K. 2010.
Listeria monocytogenes uses LAP to promote bacterial transepithelial
translocation, and induces expression of LAP receptor Hsp60. Infection and
Immunity 78(12):5062-5073.
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Jagadeesan, B., Koo, O.K., Kim, K.-P.,
Burkholder, K.M., Mishra, K.K., Aroonnual, A., and Bhunia, A.K. 2010. LAP, an
alcohol acetaldehyde dehydrogenase enzyme in Listeria promotes bacterial
adhesion to enterocyte-like Caco-2 cells only in pathogenic species.
Microbiology-UK. 156 (9):2782–2795.
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Burkholder, K.M., Kim, K-P., Mishra, K.,
Medina, S., Hahm, B-K., Kim, H., and Bhunia, A.K. 2009. Expression of LAP, a
SecA2-dependent secretory protein, is induced under anaerobic environment.
Microbes and Infection 11:859-867.
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Koo, O.K., Liu, Y., Shuaib, S., Bhattacharya,
S., Ladisch, M.R., Bashir, R., and Bhunia, A.K. 2009. Targeted capture of
pathogenic bacteria using mammalian cell receptor coupled with
dielectrophoresis on biochip. Analytical Chemistry 81:3094-3101.
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Banerjee, P., Lenz, D., Robinson, J.P, Rickus,
J.L., and Bhunia, A.K. 2008. A novel and simple cell-based detection system
with collagen-encapsulated B-lymphocyte cell line as a biosensor for rapid
detection of pathogens and toxins. Laboratory Investigation 88:196-206.
Profile Details
Last Updated: March,
2021