Dr. Francisca Mutapi

University of Edinburgh, UK

Email: f.mutapi@ed.ac.uk

Qualifications

1997 Ph.D., University of Oxford, Biological Sciences

1991 B.Sc., University of Zimbabwe, Biological Sciences

Publications (Selected)

1. Mutapi, F., Imai, N., Nausch, N., Bourke, C.D., Rujeni, N., Mitchell, K.M., Midzi, N., Woolhouse, M.E.J., Maizels, R.M., Mduluza, T.  (2011). Autoimmune reactivity is inversely related to intensity of schistosome infection. PLoS ONE 6(5): e19149.
2. Nausch, N., Mduluza, T., Midzi, N., Maizels, R.M., Mutapi, F. (2011).Regulatory and Activated T Cells in Human Schistosoma haematobium Infections. PloS One. 10; 6(2)
3. Mutapi, F., Bourke, C.D., Harcus, Y.H., Midzi, N., Mduluza, T., Turner, C.M., Burchemore, R., Maizels, R. (2011) Differential recognition of Schistosoma haematobium adult worm antigens by the human antibodies IgA, IgE, IgG1 and IgG4.  Parasite Immunology 33(3):181-92.
4. Bourke, C.D., Maizels, R., Mutapi, F. (2011). Heterogeneity in the acquired immune responses to human helminth infection.  Parasitology 138(2):139-59
5. Milner, T., Reilly, L.J., Nausch, N., Midzi, N., Mduluza, T., Maizels, R.M., Mutapi, F. (2010). Circulating cytokine levels and antibody responses to human Schistosoma haematobium: contrasting profiles with age and infection intensity. Parasite Immunology. 32(11-12
6. Midzi, N., Mtapuri-Zinyowera, S., Mapingure, M.P., Sangweme, D., Chirehwa, M.T., Brouwer, K.C., Mudzori, J. Hlerema, G., Mutapi, F., Kumar, N., Mduluza, T. (2010). Consequences of polyparasitism on anaemia among primary school children in Zimbabwe. Acta Tropica, 115(1-2):103-11
7. Mduluza, T., Mutapi F., Ruwona, T., Kaluka, D. , Midzi, N., Ndhlovu,  P.D. (2010). Similar cellular responses after treatment with either praziquantel or oxamniquine in Schistosoma mansoni infection. Malawi Medical Journal  21(4):125
8. Reilly, L.J., Magkrioti, C., Cavanagh, D.R Mduluza,T.,  Mutapi, F. (2008). Effect of treating Schistosoma haematobium infection on Plasmodium falciparum-specific antibody responses. BMC Infectious Diseases 8:158.  status conferred by the journal.
9. Midzi, N., Sangweme, D., Zinyowera, S., Mapingure, M.P., Brouwer, K.C., Munatsi, A., Mutapi F., Mudzori, J., Kumar N., Woelk, G., Mduluza, T. (2008). The burden of polyparasitism among primary schoolchildren in rural and farming areas in Zimbabwe. Transactions of the Royal Society and Tropical Medicine 102(10):1039-45
10. Mutapi, F., Burchmore R., Mduluza, T., Midzi, N., Turner, C.M.R., Maizels, R.M. (2008). Age-related and infection intensity–related shifts in antibody recognition of defined protein antigens in a schistosome-exposed population.  Journal of Infectious Diseases 198:167-75.
11. Mitchell, K., Mutapi ,F., Woolhouse, M.E.J. (2008). The predicted impact of immunosuppression upon population age-intensity profiles for schistosomiasis. Parasite Immunology 30(9):462-70.
12. Midzi, N., Sangweme, D., Zinyowera, S., Mapingure, M.P., Brouwer, K.C., Kumar, N., Mutapi, F., Woelk, G., Mduluza, T. (2008). Efficacy and side effects of praziquantel treatment against Schistosoma haematobium infection among primary school children in Zimbabwe. Transactions of the  Royal Society of Tropical Medicine and Hygiene 102(8):759-66.
13. Mutapi, F., Winborn, G., Midzi N., Taylor, M., Mduluza, T., and Maizels, R.M. (2007). T cell cytokine responses to Schistosoma haematobium in a Zimbabwean population: contrasting profiles for INF-γ, IL-4, IL-5 and IL-10 with age. BMC Infectious Diseases 7:13.
14. Mutapi, F., Roussilhon, C., Mduluza, T., Druilhe, P. (2007). Anti-malaria humoral responses in children exposed to Plasmodium falciparum and Schistosoma haematobium. Memorias do Instituto Oswaldo Cruz 102(3):405-9.
15. Dolecková, K., Kasný, M., Mikes, L., Mutapi, F., Stack, C., Mountford, A.P., Horák, P. (2007). Peptidases of Trichobilharzia regenti (Schistosomatidae) and its molluscan host Radix peregra S. Lat. (Lymnaeidae): construction and screening of cDNA library from intramolluscan stages of the parasite. Folia Parasitologica 54(2):94-8.
16. Mutapi, F., Mduluza, T., Gomez-Escobar N., Gregory, W. B., Fernandez, C., Midzi, N., Maizels, R.M. (2006). Immuno-epidemiology of human Schistosoma haematobium infection: preferential IgG3 antibody responsiveness to a recombinant antigen dependent on age and parasite burden. BMC Infectious Diseases 6(1): 96.

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