Prof. Demetrios Kouretas

Department of Biochemistry-Biotechnology, Animal Physiology

University of Thessaly, Greece



1990-1992 Postdoctor, Harvard Medical School, USA

1989 Ph.D., Biochemistry, University of Thessaloniki, Greece
1985 B.Sc., Pharmacy, University of Patras, Greece

Publications (Selected)

  1. NikolaidisMG, Jamurtas AZ, Paschalis V, Kostaropoulos IA, Kladi-Skandali A, Balamitsi V, Koutedakis Y, Kouretas D. Exercise-induced oxidative stress in G6PD-deficient individuals. Med Sci Sports Exerc. 2006 38(8):1443-50.
  2. Fatouros IG, Destouni A, Margonis K, Jamurtas AZ, Vrettou C, Kouretas D, Mastorakos G, Mitrakou A, Taxildaris K, Kanavakis E, Papassotiriou I. Cell-free plasma DNA as a novel marker of aseptic inflammation severity related to exercise overtraining. Clin Chem. 2006 52(9):1820-4.
  3. Jamurtas AZ, Theocharis V, Koukoulis G, Stakias N, Fatouros IG, Kouretas D, Koutedakis Y. The effects of acute exercise on serum adiponectin and resistin levels and their relation to insulin sensitivity in overweight males. Eur J Appl Physiol. 2006 97(1):122-6.
  4. Kostaropoulos IA, Nikolaidis MG, Jamurtas AZ, Ikonomou GV, Makrygiannis V, Papadopoulos G, Kouretas D. Comparison of the blood redox status between long-distance and short-distance runners. Physiol Res. 2006;55(6):611-6.
  5. Veskoukis A.S., Kouretas D., Panoutsopoulos G.I. Substrate specificity of guinea pig liver aldehyde oxidase and bovine milk xanthine oxidase for methyl- and nitrobenzaldehydes. Eur J Drug Metab Pharmacokinet. (2006) Jan-Mar; 31(1):11-6.
  6. Stagos D., Umstead T.M., Phelps D.S., Skaltsounis L., Charoutounian S., Floros J., Kouretas D. Inhibition of ozone-induced SP-A oxidation by plant polyphenols. Free Radical Research (2007), 41(3):357-366.
  7. Kyparos A, Salonikidis K, Nikolaidis MG, Kouretas D. Short duration exhaustive aerobic exercise induces oxidative stress: a novel play-oriented volitional fatigue test. J Sports Med Phys Fitness. 2007 47(4):483-90.
  8. Stagos D., Spanou C., Margariti M., Stathopoulos C., Mamuris Z., Kazantzoglou G., Magiatis P., Kouretas D. Cytogenetic effects of grape extracts and plant polyphenols on MMC-induced SCEs in human blood lymphocytes. Journal of Agricultural and Food Chemistry (2007), 55:5246-5252.
  9. Gougoura S, Nikolaidis MG, Kostaropoulos IA, Jamurtas AZ, Koukoulis G, Kouretas D. Increased oxidative stress indices in the blood of child swimmers. Eur J Appl Physiol. 2007 100(2):235-9.
  10. Paschalis V, Nikolaidis MG, Fatouros IG, Giakas G, Koutedakis Y, Karatzaferi C, Kouretas D, Jamurtas AZ. Uniform and prolonged changes in blood oxidative stress after muscle-damaging exercise. In Vivo. 2007 21(5):877-83.
  11. Metsios GS, Flouris AD, Jamurtas AZ, Carrillo AE, Kouretas D, Germenis AE, Gourgoulianis K, Kiropoulos T, Tzatzarakis MN, Tsatsakis AM, Koutedakis Y. A brief exposure to moderate passive smoke increases metabolism and thyroid hormone secretion. J Clin Endocrinol Metab. 2007 92(1):208-11.
  12. Nikolaidis MG, Kyparos A, Hadziioannou M, Panou N, Samaras L, Jamurtas AZ, Kouretas D. Acute exercise markedly increases blood oxidative stress in boys and girls. Appl Physiol Nutr Metab. 2007 32(2):197-205.
  13. Nikolaidis MG, Paschalis V, Giakas G, Fatouros IG, Koutedakis Y, Kouretas D, Jamurtas AZ. Decreased blood oxidative stress after repeated muscle-damaging exercise. Med Sci Sports Exerc. 2007 39(7):1080-9.
  14. Michailidis Y, Jamurtas AZ, Nikolaidis MG, Fatouros IG, Koutedakis Y, Papassotiriou I, Kouretas D. Sampling time is crucial for measurement of aerobic exercise-induced oxidative stress. Med Sci Sports Exerc. 2007 39(7):1107-13.
  15. Margonis K, Fatouros IG, Jamurtas AZ, Nikolaidis MG, Douroudos I, Chatzinikolaou
  16. A, Mitrakou A, Mastorakos G, Papassotiriou I, Taxildaris K, Kouretas D. Oxidative stress biomarkers responses to physical overtraining: implications for diagnosis. Free Radic Biol Med. 2007 43(6):901-10.
  17. Nikolaidis MG, Jamurtas AZ, Paschalis V, Fatouros IG, Koutedakis Y, Kouretas D. The effect of muscle-damaging exercise on blood and skeletal muscle oxidative stress: magnitude and time-course considerations. Sports Med. 2008 38(7):579-606.
  18. S. Veskoukis, M. G. Nikolaidis, A. Kyparos, D. Kokkinos, C. Nepka, S. Barbanis and D. Kouretas, Effects of xanthine oxidase inhibition on oxidative stress and swimming performance in rats, 2008, Appl. Physiol. Nutr. Metab., 33: 1140-1154.
  19. Spanou, N. Aligiannis, A-L. Skaltsounis and D. Kouretas, Effect of Leguminosae family plant extracts and polyphenolic fractions on Topoisomerase I-induced nicking of DNA, 2008, Review of Clinical Pharmacology and Pharmacokinetics, 22 (2): 336-338.
  20. Veskoukis, A.S., Nikolaidis, M.G., Kyparos, A., Kokkinos, D., Varamenti, E., Kouretas, D. The effect of allopurinol on protein carbonyls and swimming performance in rats. Review of Clinical Pharmacology and Pharmacokinetics, 2008 22(2):360-362.
  21. Spanou, D. Stagos, N. Aligainnis and D. Kouretas, Influence of potent antioxidant Leguminosae family plant extracts on growth and antioxidant defence system of Hep2 cancer cell line, 2009, Journal of Medicinal Food, 13(1):149-155.
  22. Kyparos A, Vrabas IS, Nikolaidis MG, Riganas CS, Kouretas D. Increased oxidative stress blood markers in well-trained rowers following two thousand-meter rowing ergometer race. J Strength Cond Res. 2009 23(5):1418-26.
  23. Kabasakalis A, Kalitsis K, Nikolaidis MG, Tsalis G, Kouretas D, Loupos D, Mougios V. Redox, iron, and nutritional status of children during swimming training. J Sci Med Sport. 2009 12(6):691-6.
  24. Veskoukis AS, Nikolaidis MG, Kyparos A, Kouretas D. Blood reflects tissue oxidative stress depending on biomarker and tissue studied. Free Radic Biol Med. 2009 47(10):1371-4.
  25. Fatouros IG, Chatzinikolaou A, Douroudos II, Nikolaidis MG, Kyparos A, Margonis K, Michailidis Y, Vantarakis A, Taxildaris K, Katrabasas I, Mandalidis D, Kouretas D, Jamurtas AZ. Time-Course of Changes in Oxidative Stress and Antioxidant Status Responses Following a Soccer Game. J Strength Cond Res. 2009 24(12):3278-86.
  26. A.S. Veskoukis, A. Kyparos, D. Stagos, D. Kouretas, Differential effects of xanthine oxidase inhibition and exercise on albumin concentration in rat tissues, 2010, Appl Physiol Nutr Metab., 35(3):244-50.
  27. Kalafati M, Jamurtas AZ, Nikolaidis MG, Paschalis V, Theodorou AA, Sakellariou GK, Koutedakis Y, Kouretas D. Ergogenic and antioxidant effects of spirulina supplementation in humans. Med Sci Sports Exerc. 2010 42(1):142-51.
  28. Kabasakalis A, Kyparos A, Tsalis G, Loupos D, Pavlidou A, Kouretas D. Blood Oxidative Stress Markers After Ultramarathon Swimming. J Strength Cond Res. 2010 25(3):805-11.
  29. I.G. Fatouros, A.Z. Jamurtas, M.G. Nikolaidis, A. Destouni, Y. Michailidis, C. Vrettou, Douroudos II, A. Alexandra, A. Chatzinikolaou, K. Taxildaris, E. Kanavakis, I. Papassotiriou, D. Kouretas. Time of sampling is crucial for measurement of cell-free plasma DNA following acute aseptic inflammation induced by exercise, 2010, Clin Biochem., (16-17):1368-70.
  30. Spanou C, Veskoukis AS, Stagos D, Liadaki K, Anastasiadi M, Haroutounian SA, Tsouka M, Tzanakouli E, Kouretas D. Effects of grape extracts on the in vitro activity of enzymes involved in oxidative stress regulation. In Vivo. 2011 25(4):657-62.
  31. Tsarouhas K, Karatzaferi C, Tsitsimpikou C, Haliassos A, Kouretas D, Pavlidis P, Veskoukis A, Adamopoulos S, Kyriakides Z, Constantinou L, Koutedakis Y, Rentoukas E. Effects of walking on heart rate recovery, endothelium modulators and quality of life in patients with heart failure. Eur J Cardiovasc Prev Rehabil. 2011 (in press).
  32. Tsitsimpikou C, Kouretas D, Tsarouhas K, Fitch K, Spandidos DA, Tsatsakis A. Applications and biomonitoring issues of recombinant erythropoietins for doping control. Ther Drug Monit. 2011 33(1):3-13.
  33. Stagos D, Portesis N, Spanou C, Mossialos D, Aligiannis N, Chaita E, Panagoulis C, Reri E, Skaltsounis L, Tsatsakis AM, Kouretas D. Correlation of total polyphenolic content with antioxidant and antibacterial activity of 24 extracts from Greek domestic Lamiaceae species. Food Chem. Toxicol. 2012 50(11):4115-24.
  34. Aggeloussi S, Theodorou AA, Paschalis V, Nikolaidis MG, Fatouros IG, Owolabi EO, Kouretas D, Koutedakis Y, Jamurtas AZ. Adipocytokine levels in children: effects of fatness and training. Pediatr. Exerc. Sci. 2012 24(3):461-71.
  35. Tsitsimpikou C, Tzatzarakis M, Fragkiadaki P, Kovatsi L, Stivaktakis P, Kalogeraki A, Kouretas D, Tsatsakis AM. Histopathological lesions, oxidative stress and genotoxic effects in liver and kidneys following long term exposure of rabbits to diazinon and propoxur. Toxicol. 2013. 10(307):109-14
  36. Manthou E, Kanaki M, Georgakouli K, Deli CK, Kouretas D, Koutedakis Y, Jamurtas AZ.Glycemic response of a carbohydrate-protein bar with ewe-goat whey.Nutrients. 2014 12;6(6):2240-50.
  37. Matthaiou CM, Goutzourelas N, Stagos D, Sarafoglou E, Jamurtas A, Koulocheri SD, Haroutounian SA, Tsatsakis AM, Kouretas D. Pomegranate juice consumption increases GSH levels and reduces lipid and protein oxidation in human blood.Food Chem Toxicol. 2014 1;73C:1-6. [Epub ahead of print].
  38. Kolyva AS, Zolota V, Mpatsoulis D, Skroubis G, Solomou EE, Habeos IG, Assimakopoulos SF, Goutzourelas N, Kouretas D, Gogos CA. The role of obesity in the immune response during sepsis. Nutr Diabetes. 2014 4:e137.
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