Prof. Rupert Leong
Department of
Gastroenterology and Hepatology
The University
of New South Wales, Australia
E-mail: rupertleong@hotmail.com
Qualifications
2004 Fellow
of the Royal Australasian College of Physicians Doctor of Medicine, Chinese
University of Hong Kong, China
1994 Bachelor
of Medicine. Bachelor of Surgery (UWA)
Publications
(Selected)
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Fanning S, Kwok A, Jones B, Leong R. EUS aspiration needle size: smaller
is better? Gastrointest Endosc. 2010 Oct;72(4):904-5
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Paramsothy S, Leong RW. Endoscopy: Fluorescein contrast in confocal
laser endomicroscopy. Nat Rev Gastroenterol Hepatol. 2010 Jul;7(7):366-8
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Leong RW. Confocal endomicroscopy in the evaluation of celiac disease.
Endoscopy. 2010 Jul;42(7):606
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Koo JH, Arasaratnam MM, Liu K, Redmond DM, Connor SJ, Sung JJ, Leong RW.
Knowledge, perception and practices of colorectal cancer screening in an
ethnically diverse population. Cancer Epidemiol. 2010 Jun 25
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Gearry RB, Day AS, Barclay ML, Leong RW, Sparrow MP. Azathioprine and
allopurinol: A two-edged interaction. J Gastroenterol Hepatol. 2010
Apr;25(4):653-5
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Ooi CJ, Fock KM, Makharia GK, Goh KL, Ling KL, Hilmi I, Lim WC, Kelvin
T, Gibson PR, Gearry RB, Ouyang Q, Sollano J, Manatsathit S, Rerknimitr R, Wei
SC, Leung WK, de Silva HJ, Leong RW; Asia Pacific Association of
Gastroenterology Working Group on Inflammatory Bowel Disease. The Asia-Pacific
consensus on ulcerative colitis. J Gastroenterol Hepatol. 2010 Mar;25(3):453-68
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Leong RW, Kamm MA, Hu PJ, Sung JJ; Asia Pacific Inflammatory Bowel
Disease Working Party. Inflammatory bowel disease in Asia. J Gastroenterol
Hepatol. 2010 Mar;25(3):436-8
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Leong RW Environmental risk factors in inflammatory bowel disease. J
Gastroenterol Hepatol. 2010 Feb;25(2):227-8
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Fanning SB, Chapman G, Yau Y, Leong RW. Education and imaging.
Gastrointestinal: Improvement of granuloma annulare with anti-tumour necrosis
factor alpha therapy for Crohn's disease. J Gastroenterol Hepatol. 2010
Jan;25(1):215
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Humphris J, Swartz D, Leong RW. New endoscopic technology: confocal
endomicroscopy. Gastrointestinal Endoscopy Review Letters 2009 (invited)
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Leong RW, Chang D, Merrett ND, Biankin AV. Taking optical biopsies with
confocal endomicroscopy. J Gastroenterol Hepatol. 2009 Nov;24(11):1701-3
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Tee HP, Swartz D, Tydd T, Leong RW. Gastrointestinal: Eosinophilic
enteritis manifesting as brown-pigmented duodenal ulcers. J Gastroenterol
Hepatol. 2009 Dec;24(12):1892
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Koo JH, Leong RW. Sex differences in epidemiological, clinical and
pathological characteristics of colorectal cancer. J Gastroenterol Hepatol.
2009 Oct 27
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Sharifian A, Humphris J, Leong RW, Jones DB. Education and imaging.
Gastrointestinal: Mycobacterium genavense enteritis in an immunosuppressed
patient. J Gastroenterol Hepatol 2009;24:1474
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Paramsothy S, Papdopoulos G, Mollison LC, Leong RW. Resumption of oral
intake following percutaneous endoscopic gastrostomy. J Gastroenterol Hepatol
2009; 24(6):1095-7
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Chang DK, Nguyen NQ, Merrett ND, Dixson H, Leong RW, Biankin AV. Role of
endoscopic ultrasound in pancreatic cancer. Expert Rev Gastroenterol Hepatol.
2009 Jun;3(3):293-303
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Leong RWL. Differences in peptic ulcer between the East and the West.
Gastroenterol Clin North Am. 2009 Jun;38(2):363-79
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Chang DK, Johns AL, Merrett ND, Gill AJ, Colvin EK, Scarlett CJ, Nguyen
NQ, Leong RWL, Cosman PH, Kelly MI, Sutherland RL, Henshall SM, Kench JG, Biankin
AV on behalf of the NSW Pancreatic Cancer Network. Margin Clearance and Outcome
in Resected Pancreatic Cancer. J Clin Oncol. 2009;27(17):2855-62
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Nguyen NQ, Biankin AV, Leong RW, Chang DK, Cosman PH, Delaney P, Kench
JG, Merrett ND. Real time intraoperative confocal laser microscopy-guided
surgery. Ann Surg. 2009;249(5):735-7
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Leong RWL, Koo JH. Colorectal cancer in inflammatory bowel disease. J
Gastroenterol Hepatol. 2009 Apr;24(4):503-5
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Chow DK, Leong RW, Tsoi KK, Ng SS, Leung WK, Wu JC, Wong VW, Chan FK,
Sung JJ. Long-term follow-up of ulcerative colitis in the Chinese population.
Am J Gastroenterol. 2009 Mar;104(3):647-54
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Chow DK, Sung JJ, Tsoi KK, Wong VW, Wu JC, Leong RW, L Chan FK.
Predictors of corticosteroid-dependent and corticosteroid-refractory
inflammatory Bowel Disease: analysis of a Chinese Cohort Study. Aliment
Pharmacol Ther. 2009 Apr 15;29(8):843-54. Epub 2009 Jan 20
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Chow DK, Sung JJ, Wu JC, Tsoi KK, Leong RW, Chan FK. Upper
gastrointestinal tract phenotype of Crohn's disease is associated with early
surgery and further hospitalization. Inflamm Bowel Dis 2009 Apr;15(4):551-7
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Leung M, Piatkov, I, Rochester C, Leong RWL. Normal Thiopurine Methyl
Transferase Phenotype Testing in a Crohn´s Disease Patient with Azathioprine
Induced Myelosuppression. Int Med J 2009 Feb;39(2):121-6
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Gill AJ, Johns AL, Eckstein R, Samra JS, Kaufman A, Chang DK, Merrett
ND, Cosman PH, Smith RC, Biankin AV, Kench JG; New South Wales Pancreatic
Cancer Network (NSWPCN). Synoptic reporting improves histopathological
assessment of pancreatic resection specimens. Pathology. 2009 Feb;41(2):161-7
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Leong RWL. Continuing Medical Education Activities. Gastroenterol
2008 Dec;135(6):2141-3
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Leong RWL, Nguyen NQ, Meredith CG, Al-Sohaily S, Kukic D, Delaney PM,
Murr ER, Yong J, Merrett ND, Biankin AV. In vivo Confocal Endomicroscopy in the
Evaluation of Celiac Disease. Gastroenterol 2008 Dec;135(6):1870-6 [plus
journal cover]
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[Article selected for Faculty of 1000 Medicine www.f1000medicine.com]
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Nguyen NQ, Leong RWL. Current application of confocal endomicroscopy in
gastrointestinal disorders. J Gastroenterol Hepatol 2008;23:1483-91
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Chang DK, Merrett ND, Biankin AV; NSW Pancreatic Cancer Network.
Improving outcomes for operable pancreatic cancer: is access to safer surgery
the problem? J Gastroenterol Hepatol. 2008;23:1036-45
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Leong RW, Gearry RB, Sparrow MP. Thiopurine hepatotoxicity in
inflammatory bowel disease: the role for adding allopurinol. Expert Opin Drug
Saf. 2008;7:607-16
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Koo JH, Wong
SKC, Kneebone A, Jalaludin B, Liu K, Arasaratnam MM, Redmond D, Connor SJ, Leong
RWL. Clinical and pathologic outcomes of colorectal cancer in a
multi-ethnic population. Clin Gastroenterol Hepatol 2008;6(9):1016-21
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Koo JH, Jalaludin B, Wong SK, Kneebone A, Connor SJ, Leong RW. Improved
survival in young women with colorectal cancer. Am J Gastroenterol.
2008;103:1488-95
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Kwok A, Lam T, Katelaris P, Leong RW. Helicobacter pylori eradication
therapy: indications, efficacy and safety. Expert Opin Drug Saf. 2008;7:271-81
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Al-Sohaily S,
Leong RWL. The yield of ileoscopy in colonoscopy (editorial). J Gastroenterol
Hepatol 2008; 23: 4-5
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Chow DKL, Leong RWL, Lai LH, Wong GLH, Leung WK, Chan FKL, Sung JJY.
Changes in Crohn’s Disease Phenotype over time in the Chinese Population:
Validation of the Montreal Classification System. Inflam Bowel Dis 2008;
14:536-41
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Chow DKL,
Leong RWL. Tacrolimus in the treatment of inflammatory bowel disease. Expert
Opin Drug Saf 2007;6(5):479-486
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Holthouse DJ,
Chen F, Leong RW, Chleboun J, Hallam L. Aeromonas hydrophilia colitis mimicking
ischaemic colitis in an elderly woman. J Gastroenterol Hepatol. 2007;22:1554-5
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Chin BW, Leong
RW, Chong AK, Chieng YH, Meredith C. Inferior vena cava filter eroding into
duodenum. Gastrointest Endosc 2006;64(5):817
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Leong RWL,
Chan FKL. Drug-induced side effects affecting the gastrointestinal tract.
Expert Opin Drug Saf 2006;5:585-92
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Leong RWL,
Lawrance IC, Chow DKL, To KF, Lau JY, Wu J, Leung WK, Chan FKL, Sung JJY.
Association of Intestinal Granulomas with Smoking, Phenotype, and Serology in
Chinese Patients with Crohn’s Disease. Am J Gastroenterol 2006; 101:1024-9
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Chin BW, Grimm
M, Connor SJ, Leong RWL. Inflammatory bowel disease. Medicine Today
2006;7:14-24 plus journal cover
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Lawrance IC,
Hall A, Leong R, Pearce C, Murray K. A Comparative Study of Goblet Cell and
Pancreatic Exocrine Autoantibodies Combined with ASCA and pANCA in Chinese and
Caucasian Patients with IBD. Inflamm Bowel Dis 2005;11:890-897
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Hung LC, Ching
JY, Sung JJ, To KF, Hui AJ, Wong VW, Leong RW, et al. Long-term Outcome of
Helicobacter pylori-Negative Idiopathic Bleeding Ulcers: A Prospective Cohort
Study. Gastroenterol 2005;128:1845-50
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Leong RWL,
Lawrance IC, Ching JYL, Cheung VMY, Fung SSL, Ho JNC, Philpott J, Wallace AR,
Sung JJY. Knowledge, quality of life and use of complementary and alternative
medicine and therapies in inflammatory bowel disease: a comparison of Chinese
and Caucasian patients. Dig Dis Sci 2004;49:1672-6
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Lawrance IC,
Murray K, Hall A, Sung JJ, Leong RW. A prospective comparative study of ASCA
and pANCA in Chinese and Caucasian IBD patients. Am J Gastroenterol
2004;99:2186-94
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Leong RWL,
Smith DW, Garas G, Beaman JM, Mitchell AW, Heath DI, House AK, Jeffrey GP. A
cost-effectiveness analysis of aciclovir or ganciclovir in cytomegalovirus
universal prophylaxis in liver transplantation. Int Med J 2004;34:410-5
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Leong RW, Lau
JY, Sung JJY. The epidemiology and phenotype of Crohn’s disease in the
Chinese population. Inflam Bowel Dis 2004; 10:646-51
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Wu JC, Chan
FK, Ching JY, Leung WK, Hui Y, Leong RW, Chung SC, Sung JJ. Effect of
Helicobacter pylori eradication on treatment of gastro-oesophageal reflux
disease: a double blind, placebo controlled, randomized trial. Gut 2004;53:174-9
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Wong VWS, Leong
RW, Chan FKL. Upper gastrointestinal complications related to non-steroidal
anti-inflammatory drugs – what have we achieved so far? Digest Liver
Dis2004;36;1-3
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Leong RW,
House AK, Jeffrey GP. Chylous ascites caused by portal vein thrombosis treated
with octreotide. J Gastroenterol Hepatol 2003;18:1211-3
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Lee YT,
Walmsley RS, Leong RW, Sung JJ. Dieulafoy's lesion. Gastrointest
Endosc 2003;58:236-43
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Leong RW,
Armuzzi A, Ahmad T, Wong ML, Tse P, Jewell DP, Sung JJY. NOD2/CARD15 gene
polymorphisms and Crohn’s disease in the Chinese population. Aliment Pharm
Ther 2003;17:1465-70
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Yu J, Leung
WK, Ebert MPA, Leong RW, Tse CH, Chan MMW, Bai AHC, Malfertheiner P, Sung
JJY. Absence of Cyclin D2 expression is associated with promoter
hypermethylation in gastric cancer. Br J Cancer 2003;88:1560-5
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Leong RW, Lee
YT. Ching JYL, Sung JJY. Quality of life in Chinese patients with
inflammatory bowel disease: validation of the Chinese translation of the
inflammatory bowel disease questionnaire. Aliment Pharmacol Ther 2003;17:711-8
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Leong RW, Lee
CC, Ling TK, Leung WK, Sung JJ. Evaluation of the string test for the
detection of Helicobacter pylori. World J Gastroenterol 2003;
9:309-11
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Sung JJY, Lee
YT, Leong RW. EUS in portal hypertension. Gastrointest Endosc 2002;
56:S35-42
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Leung WK, Hung
LCT, Kwok CKL, Leong RW, Ng ACW, Ng DKK, Sung JJY. Serial urea breath
test results in patients after consumption of antibiotics for
extra-gastrointestinal infections. World J Gastroenterol 2002;
8:703-6
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Leong RW, JJY
Sung. Helicobacter and hepatobiliary diseases. Aliment Pharmacol
Ther. 2002; 16;1037-45
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Leong RW, Chan
FK, Sung JJ. Helicobacter pylori and nonsteroidal anti-inflammatory drugs.
Approaching the end of the controversy in the new millennium, or room for more
debate? J Gastroenterol. 2001;36:731-9
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Leong RW, Lee
YT, Leung WK, Sung JJY. Histologic findings after cyanoacrylate inj
ection. Gastrointest Endosc 2001; 54:751