Prof. Masayoshi Yamaguchi

Emory University School of Medicine, USA

Email: yamamasa1155@yahoo.co.jp

Qualifications

1976 Ph.D., Pharmaceutical Sciences, Shizuoka College of Pharmacy

1973 M.S., Pharmaceutical Sciences, Shizuoka College of Pharmacy

1971 B.S., Pharmaceutical Sciences, Shizuoka College of Pharmacy

Publications (Selected)

1. Masayoshi Yamaguchi: The transcriptional regulation of regucalcin gene expression. Molecular and Cellular Biochemistry, 346:147-171 (2011)
2. Masayoshi Yamaguchi, M. Neale Weitzmann: Vitamin K2 stimulates osteoblastogenesis and suppresses osteoclastogenesis by NF-κB activation. International Journal of Molecular Medicine, 27:3-14 (2011).
3. Tatyana Vikulina, Xian Fan, Masayoshi Yamaguchi, Susanne Roser-Page, Majd Zayzafoon, David M. Guidot, Ighovwerha Ofotokun, M. Neale Weitzmann: Alterations in the immuno-skeletal interface drive bone destruction in HIV-1 transgenic rats. Proceedings of the National Academy of Sciences USA, 107: 13848-13853 (2010).
4. Masayoshi Yamaguchi: Regucalcin and metabolic disorder: osteoporosis and hyperlipidemia are induced in regucalcin transgenic rats. Molecular and Cellular Biochemistry, 341: 119-133 (2010).
5. Masayoshi Yamaguchi: Role of nutritional zuinc in the prevention of osteoporosis. Molecular and Cellular Biochemistry, 338: 241-254 (2010).
6. Masayoshi Yamaguchi, M. Neale Weitzmann: The estrogen 17β-estradiol and phytoestrogen genistein mediate differential effects on osteoblastic NF-κB activity. International Journal of Molecular Medicine, 23:297-301 (2009).
7. Masayoshi Yamaguchi, M. Neale Weitzmann: The bone anabolic carotenoids p-hydroxycinnamic acid and β-cryptoxanthine NF-κB activation in MC3T3 preosteoblasts. Molecular Medicine Reports, 2: 641-644 (2009).
8. Masayoshi Yamaguchi, M. Neale Weitzmann: The bone anabolic carotenoid β-cryptoxanthin enhaces transforming growth factor-β1-induced SMAD activation in MC3T3 preosteoblasts. International Journal of Molecular Medicine, 24:671-675 (2009).
9. Masayoshi Yamaguchi: Novel protein RGPR-p117: its role as the regucalcin gene transcription factor. Molecular and Cellular Biochemistry, 327: 53-63 (2009).
10. Masayoshi Yamaguchi: β-Cryptoxanthin and bone metabolism: The preventive role in osteoporosis. Journal of Health Science, 54: 356-369 (2008).
11. Taeko Nakagawa, Masayoshi Yamaguchi: Nuclear localization of regucalcin is enhanced in culture with protein kinase C Activation in cloned normal rat kidney proximal tubular epithelial NRK52E cells. International Journal of Molecular Medicine, 21:605-610 (2008).
12. Masayoshi Yamaguchi, Yusei Takakura, Taeko Nakagawa: Regucalcin increases Ca2+-ATPase activity in the mitochondria of brain tissues of normal and transgenic rats. Journal of Cellular Biochemistry, 104: 795-804 (2008).
13. Masayoshi Yamaguchi, Yasuko Otomo, Satoshi Uchiyama, Taeko Nakagawa: Hormonal regulation of regucalcin mRNA expression in osteoblastic MC3T3-E1 cells. International Journal of Molecular Medicine, 21: 771-775 (2008).
14. Masayoshi Yamaguchi, Maya Goto, Satoshi Uchiyama, Taeko Nakagawa: Effect of zinc on gene expression in osteoblastic MC3T3-E1 cells: enhancement of Runx2, OPG, and regucalcin mRNA expressions. Molecular and Cellular Biochemistry, 312:157-66 (2008).
15. Satoshi Uchiyama, Masayoshi Yamaguchi: Anabolic effect of β-cryptoxanthin in osteoblastic MC3T3-E1 cells is enhanced with 17β-estradiol, genistein, or zinc sulfate in vitro: the unique effect with zinc on Runx2 and α1(I) collagen mRNA expressions. Molecular and Cellular Biochemistry, 307:209-219 (2008).
16. Masayoshi Yamaguchi, Ying Ling Lai, Satoshi Uchiyama, Taeko Nakagawa: Oral administration of phytocomponent p-hydroxycinnamic acid prevents bone loss in ovariectomized rats.  Molecular and Cellular Biochemistry, 311:31-36 (2008).
17. Masayoshi Yamaguchi, Satoshi Uchiyama: Combination of β-cryptoxanthin and zinc has potent effects on apoptotic cell death and suppression of bone resorption-related gene expression in osteoblastic cells. International Journal of Molecular Medicine, 22:221-228 (2008).
18. Toru Matsumoto, Yoshinori Hokari, Masayuki Hashizume, Masayoshi Yamaguchi: Effect of Sargassum horneri extract on circulating bone metabolic markers: Supplemental intake has an effect in health humans. Journal of Health Science, 54:50-55 (2008).
19. Masayoshi Yamaguchi: Role of zinc in bone metabolism and preventive effect on bone disorder. Biomedical Research on Trace Elements, 18:346-366 (2007).
20. Taeko Nakagawa, Masayoshi Yamaguchi: Overexpression of regucalcin suppresses cell response for tumor necrosis factor-α or transforming growth factor-β1 in cloned normal rat kidney proximal tubular epithelial NRK52E cells. Journal of Cellular Biochemistry, 100:1178-1190 (2007).